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Tag: "cross" at biology news

Neuronal 'traffic jam' marks early Alzheimer's disease

...eople would accumulate more than others, enough to cross a critical threshold and tip the scale toward disease." Goldstein emphasized that any application of these findings to potential diagnostic tests or new therapies remains speculative at this time. "However, if tracers could be developed that would r...

Open microfluidic and nanofluidic systems

...his way corresponds to channels with a rectangular cross section. The width and depth of these channels can be varied between a hundred nanometer and a couple of micrometer. At first sight, it seems rather obvious to use such surface channels as microcompartments. However, if one actually tries to fill th...

Antibiotic might fight HIV-induced neurological problems

...trolling HIV in blood, but most of the drugs don't cross the blood-brain barrier very well," says Christine...30 years, minocycline was specifically designed to cross the blood-brain barrier, the biological "wall" that limits what can pass from the blood into the bra...

PET/MRI scans may help unravel mechanisms of prenatal drug damage

...hat cocaine and/or its labeled metabolites readily cross the placenta. But the cocaine uptake distribution pattern observed in the fetus was very different from that of the mother. For example, mothers showed rapid uptake and clearance of the drug in the heart, kidneys and lungs, with slower uptake in the ...

Duke engineers develop new 3-D cardiac imaging probe

...rent ultrasound technology to image a single heart cross section. The new probe has considerable potential not only for evaluating the condition of the heart, but also for use in guiding therapeutic treatment devices, the researchers said. The new Duke probe can also be used to image the esophagus, rectum...

Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia

...ally expressed in ALL cells that exhibited de novo cross resistance to four widely used antileukemic agents. They went on to investigate the relationship of these genes to treatment outcome in ALL patients and found that expression of the genes was associated with treatment outcome and could be used to ide...

Low oxygen likely made Great Dying worse, greatly delayed recovery

...passes had insufficient oxygen to allow animals to cross from one valley to the next. That population fragm...is quite rapid, and animals that once were able to cross mountain passes quite easily suddenly had their movements severely restricted," Huey said. He calcu...

Scientists reveal the shape of a protein that helps retroviruses break into cells

...passes had insufficient oxygen to allow animals to cross from one valley to the next. That population fragm...is quite rapid, and animals that once were able to cross mountain passes quite easily suddenly had their movements severely restricted," Huey said. He calcu...

Rabies spread speeds up

...ead across central Ohio - compared to 48 months to cross the much smaller state of Connecticut - and cover the state within 41 months. This transmission rate - 100 kilometers/year - significantly surpasses previous estimates, which range from 30 to 60 kilometers/year. The potential for such rapid spread, i...

Amazon symposium to address large-scale conservation

...-scale, integrated approaches to conservation that cross traditional disciplinary boundaries. Large-scale conservation of the greater Amazon Basin region will depend upon (1) conservation analyses that describe the complex interactions among ecosystems, economies, and climate that will unfold into the futu...

Critical step traced in anthrax infection

... insight into the broader question of how proteins cross cell membranes. The findings appear in the July 29 issue of Science. An anthrax bacterium secretes three nontoxic proteins that assemble into a toxic complex on the surface of the host cell to set off a chain of events leading to cell toxicity and d...

Scientists discover global pattern of big fish diversity in open oceans

... the 1950's ?Japanese longline fisheries data ?and cross referencing these data with scientific observer data from the US and Australia, this study is the first to map communities of these open ocean travelers. Pelagic longlines are the most widespread fishing gear in the open ocean ?baited lines up to 10...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...h the gastrointestinal (GI) tract and then able to cross over into the bloodstream to be used by the body, according to research from the University of Southern California School of Pharmacy. This technology may allow for oral administration of drugs that previously could only be given by injection, notes...

Wild grasses and man-made wheats advance research capabilities

...Texas Wheat Producers Board. "My preference is to cross wheat with wheat," Rudd said. "The best chance for success is to cross High Plains wheat with High Plains wheat. But to get genetic variability, you cross state lines or e...

Scientists discover that three molecules may be developed into new Alzheimer's drugs

.... It is also important to find molecules that will cross the blood brain barrier. They then set up a test of nearly 400 small molecules that fit their criteria. The test results showed three small molecules that can inhibit the enzyme. These are candidates for development as drugs. Kosik explained that p...

Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels

.... It is also important to find molecules that will cross the blood brain barrier. They then set up a test of nearly 400 small molecules that fit their criteria. The test results showed three small molecules that can inhibit the enzyme. These are candidates for development as drugs. Kosik explained that p...

Identification of specific genes predicts which patients will respond to Hepatitis C treatment

... of Medical Research at University of Toronto with cross appointments in the Departments of Medical Biophysics and Medical Genetics and Microbiology. He is also a senior scientist at the Clinical Genomics Centre at the University Health Network and Director and CEO of the Structural Genomics Consortium. "W...

Compound might defeat African sleeping sickness, clinical trial beginning this month

...he new drug candidates are active because they can cross the blood-brain barrier, a biological wall that protects the nervous system naturally but can block beneficial drugs, he said. Work is also progressing rapidly on a new drug for drug-resistant malaria, another major threat in developing countries. T...

Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades

...owth of health and education infrastructure. "The cross boundary nature of the problem makes desertification a global concern ?one that receives too little attention," says co-author Zafar Adeel, Assistant Director of the United Nations University water academy in Canada, the UNU International Network on ...

Gap-climbing fruit flies reveal components of goal-driven behaviors

...y were thus forced to decide whether to attempt to cross the gap "by foot." The researchers found that the ...first visually measure the gap width and then only cross the gap if it is a traversable width. If the chasm is short, flies engage in an extraordinary crossi...

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