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Tag: "critical" at biology news

Breast-Cancer Risk Linked to Exposure to Traffic Emissions at Menarche, First Birth

...ife when exposures to potential carcinogens may be critical for breast-cancer initiation and development," said Nie. "Our study findings support the hypothesis that exposures in early life contribute to breast-cancer risk." The study was based on data from the Western New York Exposures and Breast Cancer (WE...

Children's taste sensitivity and food choices influenced by taste gene

...f taste and flavor preferences during childhood, a critical time for learning about food. Mennella comments, "Our previous studies focused on how early experience influences preferences for foods and flavors. Now, we have a tool to look at how experience and genetics interact in determining why we like the fo...

UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

...tice (GMP) suite, a specialized laboratory that is critical for the safe growth and manipulation of stem cell lines. Compliance officers oversee all research in the GMP suite, which must follow stringent federal guidelines for reintroduction of manipulated cells into the human body. In addition, UCLA's Jonss...

Researchers discover molecular mechanism that desensitizes us to cold

...cell to the cold stimulus. "This finding provides critical information to help us understand how we sense heat and cold and from that to expand our understanding of temperature regulation," said Dr. Logothetis. "Additionally, because the region of this receptor that interacts with PIP2 is found in many simil...

New online portal merges vast data on Gulf of Maine ecosystem

...lf of Maine, across space and time, and illuminate critical trends related to this important international resource," says Evan Richert, program director for the Gulf of Maine program. "The new portal is the door to a treasure of data, much of it essentially inaccessible before now. Modern technologies allow ...

Epstein-Barr virus protein crucial to its role in blood cancers

...chool of Medicine have identified a link between a critical cancer pathway and an Epstein-Barr Virus (EBV) pro...rives the cancer process has directly identified a critical component of the cell cycle for control. Now we can develop targeted therapeutics to disrupt the fun...

Defensins neutralize anthrax toxin

...chool of Medicine have identified a link between a critical cancer pathway and an Epstein-Barr Virus (EBV) pro...rives the cancer process has directly identified a critical component of the cell cycle for control. Now we can develop targeted therapeutics to disrupt the fun...

Iron exporter revealed that may explain common human disorder

The first direct evidence that a single protein is critical in the cellular export of iron may help to explain...icient for ferroportin in all tissues except those critical for maternal nutrient transfer survived but quickly became anemic after birth due to iron deficiency...

Institute for Systems Biology Symposium Addresses Need for Better Computational Tools

...ating these proteins of unknown function remains a critical bottleneck for systems biology and is crucial to understanding the biological relevance of genome-wide changes in mRNA and protein expression, protein-protein and protein-DNA interactions. World Community Grid is enabling ISB researchers to predict ...

Stopping smallpox in its tracks: A new anti-viral approach

...lopment of antiviral compounds. This is especially critical at a time when the threat of smallpox as a biological weapon is high. ...

Key mechanism in genetic inheritance during cell division identified

...s of chromosomes line up. During this phase, it is critical that the spindles maintain their structural integrity so that they can segregate a single copy of each chromosome to each daughter cell. After which, the microtubules again disassemble and reform back into skeletal systems for the two new daughter ce...

Products containing specific probes for detecting alternative splice forms protected

...cy of therapeutics. Alternative RNA Splicing is a critical step in the expression of most genes, which can result in the expression of several mRNAs encoding proteins with different functions from a single gene. Splicing events are implicated in numerous pathologies and can be altered by various stress event...

Researchers find new genes necessary to make embryo

...t and lead author of the study, "in which genes in critical positions consist largely of older components while new functions added later provide additional layers of regulation to lend adaptive functions to these core networks." ...

New insight into regulation of blood stem cells

...uption methods because loss of genes thought to be critical for this process often results in embryonic death,...or for every type of blood cell. Instead, c-Myb is critical for very distinct steps in the formation of specific types of blood cells. Most surprisingly, the c-...

New drug shows promise as powerful anticancer agent

...to develop inhibitors that block the function of a critical molecule that is required by a tumor cell to complete cell division," explains lead author Dr. E. Premkumar Reddy from Temple University School of Medicine. "One such molecule appears to be Plk1." Dr. Reddy and colleagues examined the effects of Plk...

Scientists identify molecule that regulates well-known tumor suppressor

...r activity by inhibiting PKB/Akt signaling that is critical for cell survival. Many human cancer cells exhibit mutations in the PTEN gene, but other cancers have the normal PTEN gene. While it is clear that without normal PTEN there is a loss of PKB/Akt inhibition that can lead to tumor growth, sometimes canc...

Love's all in the brain: fMRI study shows strong, lateralized reward, not sex, drive

...on where receptors for the hormone vasopressin are critical for vole pair-bonding, or attachment. "Humans have evolved three distinct but interrelated brain systems for mating and reproduction ?the sex drive, romantic love, and attachment to a long term partner," Fisher said, "and our results suggest how fee...

To control germs, scientists deploy tiny agents provocateurs

... class of proteins that are linked to AHLs and are critical in quorum sensing. "We want to design molecules to confuse bacteria so they can't sense their neighbors," says Blackwell, "but some types of quorum sensing are beneficial, so we are simultaneously searching for compounds that selectively turn on gro...

Researchers make gains in understanding antibiotic resistance

...ajor health problem," said Steitz. "It is becoming critical to understand the precise structural basis of resistance and even more important to do something about it." Steitz cited, for example, recent statistics published in the journal Nature, stating that hospitals in the United States see some two million...

Harmful chemicals may reprogram gene response to estrogen

...hat exposure to harmful chemicals and drugs during critical developmental periods early in life may actually "...ze that exposures received decades earlier, during critical developmental stages, may be much more important in determining who develops cancer as an adult." T...

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