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Tag: "course" at biology news

Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer

...(radiation to the lymph nodes and chest wall) to a course of chemotherapy after radical mastectomy in premenopausal women with lymph node–positive breast cancer. Between 1979 and 1986, 318 patients were randomly assigned to receive no radiation therapy or to receive radiation. A 15-year follow-up found that...

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

...(radiation to the lymph nodes and chest wall) to a course of chemotherapy after radical mastectomy in premenopausal women with lymph node–positive breast cancer. Between 1979 and 1986, 318 patients were randomly assigned to receive no radiation therapy or to receive radiation. A 15-year follow-up found that...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

...ings were mostly stable in number and sizeover the course of three to seven days, Brendza injected Abetaantibodies directly onto the surface of the mouse brains. In the regionof the injection, the antibodies cleared the plaques, confirmingearlier research results. Then Brendza closely monitored the swelling...

Key molecule in plant photo-protection identified

...ings were mostly stable in number and sizeover the course of three to seven days, Brendza injected Abetaantibodies directly onto the surface of the mouse brains. In the regionof the injection, the antibodies cleared the plaques, confirmingearlier research results. Then Brendza closely monitored the swelling...

Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...er adults, the patients whose disease follows this course usually die with the disease, not because of it. C...e biology of leukemic lymphocytes and the clinical course of CLL as it relates to the biology, the authors then offer a unifying hypothesis for the developmen...

Female sex hormones play a vital role in defense against sexually transmitted diseases

...ccination strategies," said Kaushic. "There is of course the flip side to this as well. Our studies in mice and in fact a number of clinical studies as well show that women who use Depo-provera, a progesterone based injectable contraceptive, have particularly high susceptibility to sexually transmitted inf...

Mouse brain tumors mimic those in human genetic disorder

... commontumor in children with NF1.Second, the time course of tumor development was similar to that seenin humans. Unlike most tumors, optic pathway gliomas associated withNF1 typically stop growing after a few years. Moreover, they almostalways occur in children ?these tumors generally start growing inchild...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

... the brain can help doctors determine early in the course of brain cancer regimen if a patient's tumor will shrink, a new study shows. Researchers at the University of Michigan Comprehensive Cancer Center developed the assessment, which they call a functional diffusion map. They used a magnetic resonance i...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...e. "Gene therapy has the potential to reverse the course of the disease with a single treatment," Koeberl said. The researchers delivered the glycogen-degrading enzyme with an adeno-associated virus (AAV) vector. AAV is not associated with any known human disease. The DNA coding for the enzyme was linked ...

Scientists decipher genome of fungus that can cause life-threatening infections

...ing cryptococcal infection at some point duringthe course of their HIV disease. The disease caused by the fungus,cryptococcosis, sometimes involves a fatal brain inflammation."In developing countries, cryptococcosis has emerged as one of the mostcommon opportunistic infections, and a leading cause of mening...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...g supply of dopamine, sidetracking the destructive course of Parkinson's disease. But eventually the treatment can backfire. “Levodopa generally works great for several years, but then it actually starts creating movement problems,?Mandel said. “Our idea is that instead of taking pills that create detrimen...

Study Models Impact Of Anthrax Vaccine

... the Bloomberg School of Public Health.“But a long course of antibiotics is not ideal, and a new improvedanthrax vaccine could be especially helpful in reducing duration ofantibiotic treatments.?...

Estrogen-like Component of Plastic Stimulates Growth of Certain Prostate Cancer Cells

...ations in their androgen receptor genes during the course ofprostate cancer treatment, although these concepts will need to beverified in animal systems,?according to Karen Knudsen, Ph.D., anassistant professor in the University of Cincinnati’s Department ofCell Biology and Center for Environmental Genetics...

New Treatment Rivals Chemotherapy For Lymphoma, Study Finds

...d with any other form of therapy received a single course of treatment with the Bexxar therapeutic regimen, ...our study, moving this treatment up earlier in the course of a patient's illness should be strongly considered instead of using it as a last resort or not at ...

Gene therapy for Parkinson's disease moves forward in animals

...g supply of dopamine, sidetracking the destructive course of Parkinson's disease. But eventually the treatment can backfire. "Levodopa generally works great for several years, but then it actually starts creating movement problems," Mandel said. "Our idea is that instead of taking pills that create detrime...

Scientists find fossil proof of Egypt's ancient climate

... "We're using the chemistry of the water over the course of a year or two, as revealed by isotopic analyses and minor element analyses of the snail shells to determine information about the climate then," Kieniewicz said. "The shell is an archive of the snail's life. The analyses give us snapshots of what ...

Rush Physicians Using Gene Therapy For Heart Patients With Moderate To Severe Chest Pains Who Do Not Benefit From Other Treatments

...od vessels, or angiogenesis, should occur over the course of four to eight weeks following the procedure which is done in the cardiac catheterization lab at Rush," said Dr. Gary L. Schaer, the principal investigator of the trial at Rush and director of the Rush Cardiac Catheterization Labs. "The patient goe...

Bone Density Recovers After Teens Stop Injected Contraceptive

...eafter for the next two to three years. During the course of the study, 61 women stopped using the contraceptive. The researchers found that DMPA users had a greater reduction in bone density findings than did non-users. Dr. Scholes explained that these bone density losses seen among the DMPA users occurr...

Expression Project for Oncology (expO) completes first phase of standardized gene expression analyses

...gene expression of 1,900 tumor biosamples over the course of 3 years. Standardization of the collection, analysis, and vocabularies will help accelerate future development of new, targeted cancer treatments. Standardization, which will take place at every phase from consent to collection to gene expression...

Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients

..., blood was taken at specific time points over the course of two years. Baranzini et al. measured the expression level of 70 genes—including a number involved in interferon interactions and immune regulation—at each time point. The authors used statistical analyses to search for gene expression profiles th...

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