RNA map provides first comprehensive understanding of alternative splicing
...ers locate. Furthermore, the location of the peaks correlated with Nova's action on regulating whether the alternative exon is spliced in or out. The researchers tested whether this RNA map was valid by asking whether it could predict how Nova would act on RNA transcripts that had yet to be discovered. They...Unraveling where chimp and human brains diverge
...fers from the chimpanzee's." By evaluating the correlated activity of thousands of genes, the UCLA team iden... the brain, the team identified gene networks that correlated to specific brain regions. Then they compared the strength of these correlations between humans and...Protein 'fingerprint' in spinal fluid could spot Alzheimer's disease
...udies have met with limited success, but most have correlated their findings with patient's clinical symptoms rather than working with the gold-standard of autopsy-proven Alzheimer's," notes Norman Relkin, M.D., associate professor of clinical neurology and neuroscience at Weill Cornell and director of the Memo...Researchers discover mechanism that determines when detailed memories are retained
...gher level of acetylcholine during a learning task correlated with more details of the experience being remembered. The results are the first to tie levels of acetylcholine to memory specificity and could have implications in the study and treatment of memory-related disorders. The findings appear in the Nov...Protein folding: Building a strong foundation
...ggest that thermodynamics and kinetics are closely correlated in proteins and appear to have co-evolved for optimizing both the folding rate and the stability of proteins." Wittung-Stafshede's group, which specializes in experimental studies related to protein folding, tested the model's predictions against e...Pleasure and pain: Study shows brain's 'pleasure chemical' is involved in response to pain too
...lia ?the putamen and caudate nucleus ?was strongly correlated with the rating of how intense and unpleasant the pain itself was on a scale of 0 to 100. The authors concluded that in some areas of the basal ganglia, dopamine was involved in the assessment of pain itself, while in the ventral area, or nucleus acc...Pair of microRNA molecules controls major oncogene in most common leukemia
...ype to treat. They found that TCL1 over-expression correlated with the two most aggressive forms of the cancer. To determine which miRNAs targeted TCL1, they used microRNA-microchips and elaborate computer programs to identify miR-29 and miR-181. Regulation of TCL1 expression by these two miRNAs is relevant...Brains can recover from alcoholic damage but patients should stop drinking as soon as possible
...gnificantly. The increase of the nerve cell marker correlated with the patients performing better in a test of a... increased by about 10%. Brain volume regeneration correlated with the percentages increase in choline, indicating that volume regain is driven primarily by risin...Mayo Clinic study suggests that a central nervous system viral infection can lead to memory deficits
...nable damage to complete devastation, was directly correlated to the number of dead brain cells in the hippocamp..." Dr. Howe says. "Because hippocampus injury was correlated with reduced spatial memory formation across a range of damage and a range of memory performance, we...Honey bee genome holds clues to social behavior
...vestigate whether particular transcription factors correlated with genes that were differentially expressed (turned on or off) between nurse bees and foragers. "We found five different transcription factors that showed a statistically significant correlation with socially regulated genes," Sinha said. "It app...Smoking changes brain chemistry
...ether or not the patient used a nicotine patch and correlated directly with the patient's smoking history: the greater the number of pack years (one pack per day for one year equals one pack year), the lower the NAA level. "The ACC is involved in mediating conditioned reinforcement, craving and relapsing be...High dopamine transporter levels not correlated with ADHD
...t hyperactivity disorder (ADHD) are not positively correlated with the disease. In fact, the study found lower levels of these "dopamine transporter" proteins in certain brain regions of ADHD patients compared with controls. The study, which will be published in an upcoming issue of the journal Neuroimage and i...Melatonin improves mood in winter depression
...dvance direction. Symptom severity in SAD patients correlated with the misalignment in either direction. The treatment of choice for most SAD patients is bright light exposure, which causes phase advances when scheduled in the morning. Because patients know when they are exposed to bright light, however, there......ed unequivocally; thus, those beliefs could not be correlated with brain function. However, the researchers' statistical analysis of the subject's navigation decisions enabled them to infer which of two "cognitive states" the subject was in, to give the researchers insight into which cortical regions were acti...... upstream to breed and feed. The observations also correlated with earlier studies suggesting that sea slugs flatten out their bodies to reduce drag when they encounter strong water currents, a behavior that helps them avoid being swept away. At field sites near Vargas Island, British Columbia, and in souther...Precision biochemistry tracks DNA damage in fish
...ut of a 100 million bases in one case. The results correlated well with earlier research and revealed similar damage to liver DNA (more likely tied to the fish's food) and gill DNA (more probably reflecting pollutants in water). The results suggest that these DNA lesions, and others like them, can be used as v...Carnegie Mellon researchers discover key deficiencies in brains of people with autism
... of the white matter -- was found to be positively correlated with functional connectivity, which is the synchro...m, and that structural connectivity was positively correlated with functional connectivity. The authors believe that the heavy reliance on visualization by people...Coming soon: 3-D imaging that flies 'through' and 'around' cancer
...ether, the functional data from the PET imaging is correlated with anatomy on the CT images to provide a single detailed and informative image. Standard 2-D PET and PET/CT images (with FDG) are accurate for evaluating lung and colorectal cancer; however, they lack the anatomic information that can be provided...New study reveals signaling pathways required for expansion of pancreas stem cells
...of AR42J progenitor cells, and that this growth is correlated with an increase in Id expression. The group also did immunohistochemistry staining to show that BMP and Id proteins are found in abundance in the embryonic mouse pancreas, which contains proliferating stem cells. A possible source of pancreatic pr...