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Tag: "correlated" at biology news

CSIRO scientists join fight to save 'Tassie devil'

... or structural changes can be detected that can be correlated with the disease. “We are hoping we can work together to develop a pre-clinical diagnostic test based on recent developments in the diagnosis of human breast cancer,” Dr Church said. “Such a test would enable the screening of captured animals pr...

454 sequencing identifies HIV drug resistance at early stage

... Statistical Center at the University of Minnesota correlated the sequence data with the patient outcomes, to which 454 Life Sciences was blinded. “454 Sequencing can instantly generate hundreds of thousands of long clonal sequence reads that accurately enable the sensitive detection of rare mutations” expl...

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state

...archers looked for genes whose expression was also correlated with the master stem cell regulator gene Oct4. They also applied very rigorous analysis methods, using data from StemBase, the largest stem cell gene expression database in the world. Designed by bioinformaticist Dr. Miguel Andrade, the database incl...

Gene therapy study shows safety and statistically significant improvement in Parkinson's disease

... of between 40% and 65%. Clinical improvement also correlated well to metabolic changes in glucose utilization as measured by PET scan. The PET scan data revealed a significant improvement (p<0.001) in brain metabolism on the treated side of the brain compared to the untreated side. No adverse events relate...

Pistachios lower cholesterol, provide antioxidants

...e increased lutein from the 3-ounce pistachio diet correlated with a reduction in oxidized LDL which may indicate that the lutein in pistachio nuts improves the risk of cardiovascular disease by reducing serum oxidized LDL. "Our study has shown that pistachios, eaten with a heart healthy diet, may decrease a...

Genetic roots of bipolar disorder revealed by first genome-wide study of illness

... into account. One of the genes the researchers correlated with the disorder, DGKH, is active in a biochemical pathway through which lithium is thought to exert its therapeutic effects. The gene produces an enzyme (diacylglycerol kinase eta) that functions at a point closer to the root of the lithium-sensit...

DNA-damage test could aid drug development

...een studied by Samson's lab, and found the results correlated well with results from the existing test. Additionally, he experimented with mutant mice created by Samson's lab that are deficient in certain DNA-repair systems. The bone marrow cells derived from these mice, and the cells cultured from that bone ma...

UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice

...ate slowed in the treated animals, a response that correlated closely with heat dose. No toxicity related to the bioprobes was observed. "Using heat to kill cancer cells isn't a new concept," DeNardo said. "The biggest problems have been how to apply it to the tumor alone, how to predict the amount needed an...

Twin studies reveal genetic components leading to cardiac and kidney disease

...’Connor’s team has identified three genes that are correlated with systemic inflammation. This study indicates a strong effect of heredity in the occurrence of C-reactive protein or CRP, a blood protein that serves as a marker for inflammation. Its presence indicates a heightened state of inflammation in the b...

Inflammation may play role in metastasis of prostate cancer

...n was also seen in human prostate cancer, and both correlated with the clinical stage of the disease. Karin and his colleagues discovered a signaling pathway that increased metastases in a mouse model of prostate cancer. The pathway is activated by a ligand that binds to a Receptor that Activates Nuclear fa...

Surgeons with video game skill appear to perform better in simulated surgery skills course

...ns and 21 surgical residents, video game skill was correlated with laparoscopic surgery skill as assessed during a simulated surgery skills course, according to a report in the February issue of Archives of Surgery, one of the JAMA/Archives journals. James C. Rosser Jr., M.D., of Beth Israel Medical Center, Ne...

Tiny clue reveals new path toward heart disease

...ve found that this particular SNP is significantly correlated with the degree of atherosclerosis in human aortas, the large blood vessel that brings blood from the heart to all parts of the body. Kalirin contains the hereditary information for the production of a protein that is involved in the migration of ...

Mother knows best: Plant knowledge key to childhood health in remote Amazon

...ults, with knowledge of local plants significantly correlated with childhood health and nutrition. To a great extent, Tsimane survival and well being is dependent on their knowledge of local plants, in everything from managing their environment to getting food and preventing and curing disease, explained Rey...

Fish growth changes enhanced by climate change

... Dr Thresher said slower growth in fishes has been correlated with a variety of life history traits ?from higher mortality to reduced food availability and increased age or smaller size at sexual maturity. He said comparisons of historical and modern oceanographic data indicate temperature trends very simila...

Genes and genius: Researchers confirm association between gene and intelligence

... several variations within the CHRM2 gene could be correlated with slight differences in performance IQ scores, ...eir biological parents, their IQs are more closely correlated to biological parents, with whom they share genes, than adoptive parents, with whom they share an en...

Cancer cells forming blood vessels send their copper to the edge

...mages of the cells, Finney and her colleagues then correlated elemental content with cellular structures. "Our findings were very clear," said Finney. "We observed a dramatic relocalization of between 80 and 90 percent of cellular copper to the tips of the tendril-like projections angiogenic cells send out b...

Proteins may predict lung transplant rejection

... some previously unidentified proteins were highly correlated with chronic lung rejection. In particular, the researchers found that HNP was three times more likely to be elevated among those who later suffered chronic rejection. Later analyses identified 265 proteins that were upregulated in lung rejection ...

Evolution of Old World fruit flies on three continents mirrors climate change

...nd that the frequency of particular inversions was correlated with the latitude where a given insect was found. Inversions that were common in the north were uncommon in the south, and vice versa. The fruit flies were accidentally introduced to the Pacific Coast of Chile in the late 1970s and to the North Am...

New brain-chemistry differences found in depressed women

...n of that system, and the level of that activation correlated with the intensity of their negative emotional state brought on by the sad memories. Among the non-depressed women, the mu-opioid system was actually less active in some parts of the brain than it had been before they recalled sad memories. The r...

Why do some queen bees eat their worker bee's eggs?

...ound no evidence that multiple mating by the queen correlated with reduced rearing of workers' sons or greater worker reproductive policing. Were the textbooks wrong" A new study appearing in the current issue of The American Naturalist strongly supports Hamilton's original theory. Tom Wenseleers and Francis...

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