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Tag: "correlate" at biology news

Cigarette smoke alters DNA in sperm, genetic damage could pass to offspring

...ere genes reside, Yauk notes that previous studies correlate mutations in non-coding regions with those in coding regions, and that some repetitive regions of DNA (not exam-ined in this study) are associated with genes. “It stands to reason that mutations could also interfere with genes, but our ongoing re...

Study shows lizard moms dress their children for success

...scribed three different behavioral strategies that correlate with throat color in side-blotched lizards. Orange-throated males are highly aggressive and usurp territory from other lizards; yellow-throated males sneak into the territories of other males to mate with females; and blue-throated males form partner...

Deconstructing brain wiring, one neuron at a time

...inarily complex architecture of the brain and then correlate these neural circuits with such brain functions as perception and behavior. But these circuits are difficult to unravel because dozens of different neuronal types are entangled within a precisely connected network, and even neighboring neurons of the...

Using nanomagnets to enhance medical imaging

...nd how to control contrast properties. Researchers correlate the measured properties to the observed MRI response under non-clinical conditions using imagers at The Children's Hospital in Denver. The information gained is fed back into recipes for making even better nanomagnets. The work described in the new p...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

... lines to the drugs. For Lapatinib, the strongest correlate of response was amplification and over expression of ErBB2, consistent with clinical experience. For CI-1040, changes in the MEK pathway were most strongly associated with response. Predictors based on combinations of molecular correlates of respon...

How fish conquered the ocean

... gene duplication to form paralogous clusters that correlate to the pelagic and benthic character of the eggs. The alteration in the function (neo-functionalization) of one of the duplicated genes (paralogues) allowed its yolk protein products to be broken down to free amino acids and thus drive hydration of t...

Volcanic eruptions, ancient global warming linked

...ded. "Similarly large submarine volcanic events correlate with major marine anoxic events ?periods of no oxygen in the deep-ocean water ?which we think are triggered by high surface productivity of plankton that have responded to nutrients released into the ocean by hydrothermal activity," Duncan said....

Peering into the shadow world of RNA

...00 genes. Interestingly, most of the editing sites correlate with non-coding regions of DNA, the so-called junk DNA.? One reason for this, Nishikura and others speculate, may be that the majority of these non-coding regions are composed of repetitive sequences of DNA called transposons. The largest class of ...

'GreeneChip' -- New diagnostic tool that rapidly and accurately identifies multiple pathogens

...ogen and its properties, the GreeneChip contains a correlate of its genetic makeup. GreeneChip performance was initially tested by using samples obtained from patients with respiratory disease, hemorrhagic fever, tuberculosis, and urinary tract infections. In all cases, GreeneChip analysis detected an ag...

Teenager moves video icons just by imagination

...ta which parts of the brain and what brain signals correlate to these movements. They then asked the boy to play a simple, two-dimensional Space Invaders game by actually moving his tongue and hand. He was then asked to imagine the same movements, but not to actually perform them with his hands or tongue. When...

Longer-lived rodents have lower levels of thyroid hormone

...rs wrote. "Significant declines in thyroid hormone correlate well with enhanced maximum lifespan." The study...groups "These hormone concentration differences correlate with maximum species lifespan and suggest an important regulatory role of thyroid hormone in longevi...

First biomarker for human sleepiness identified in fruit flies

...We're very pleased with how tightly amylase levels correlate with sleep debt, but for a good diagnostic test we're likely going to need more than one biomarker," Shaw says. "So we're going to continue to use the processes that we've developed to look for other substances that change in connection with the leve...

Amateur boxing linked to brain cell injury

...eneration and damage, and the increase is known to correlate with the size of the brain lesion," the authors write. "When applied to the results of this study, the increases in neurofilament protein and total tau probably reflect damage to neuronal axons from hits to the head during a bout." They also had el...

High-throughput oncogene mutation detection in human cancers by mass spectrometry-based genotyping

...ngle letter (or nucleotide) changes in genes might correlate with disease risk in normal individuals, the researchers adapted it to look for known point mutations in genes that make them oncogenic. They chose oncogenes known to contain "dominant activating mutations in many tumor types. In a lot of cases, t...

Mayo Clinic: Gene expression profiling not quite perfected in predicting lung cancer prognosis

...h are related to tumor differentiation and may not correlate with clinical outcomes; conversely, genes expressed at low levels or in a subtle difference are often overlooked, which may be quite relevant biologically to clinical questions. The authors of the study recommend that medical scientists engag...

Antioxidant protects against lung damage in silicosis

...ndicate that silicosis patients' serum HO-1 levels correlate significantly with their primary lung function test level and vital capacity. (Vital capacity is the maximum amount of air that can be exhaled after a maximum inhalation, showing the status of lung tissue.) The authors believe that if serum HO-1 d...

History-hunting geneticists can still follow familiar trail

...rench scientists agreed that protein diversity did correlate with population size. All that remained for UF ... work for 20 years, and to think that mtDNA didn't correlate with population size was clearly going against the dogma. This study shows the dogma is safe in mamm...

Chemotherapy temporarily affects the structures of the human brain

... brain changes are observable within 12 months and correlate with receiving chemotherapy rather than a secondary effect of the cancer, although it cannot be concluded because of several limitations caused by the study design. However, these structural changes to the central nervous system were not sustained fo...

Complexity constrains evolution of human brain genes

...ose from mice. They explained the trend as a correlate of smaller population size in the more advanced species. Species with smaller population size can more easily escape the harsh scrutiny of natural selection. When they compared the pace of evolution among genes expressed in the brain, however, th...

Bacteria can help predict ocean change

...talina Island. They used statistical methods to correlate the bacteria counts with the Wrigley Institute's monthly measurements of water temperature, salinity, nutrient content, plant matter and other variables. The researchers found they could predict the makeup of the bacterial population by the conditi...

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