Stroke study sheds light on left-right brain divide
...s. The group with damage to the left frontal lobes corrected 68% of mistakes in the test, whereas people with right-brain damage only made corrections to 30% of their errors. This suggests that people who suffer damage to their right frontal lobe following a stroke may struggle in everyday situations which req...It's OK for men with high blood pressure to have a drink or two, new study finds
... the editorial writers say, "we cannot assume that corrected estimates of diet-disease associations in any single study are definitive." ...Loss of a universal tRNA feature reported
... the alphaproteobacteria group. Examination of the corrected tRNAHis sequences revealed that a group of alphaproteobacteria fails to encode a G (guanylate) at the -1 position of the tRNA as all other bacteria do. Amplification and tRNA sequencing approaches were used to confirm the findings. Sinorhizobium m...Are one-third of costly implanted heart devices unnecessary? New study suggests yes
... in death risk were present even after the authors corrected for many other variables and differences between the two MTWA-positive and MTWA-negative groups. Chan and his Ohio colleagues, led by first author Theodore Chow, M.D., FACC, of the Lindner Clinical Trial Center at Christ Hospital and the OHVC, ha...Major link in brain-obesity puzzle found
... that restoring SH2B1 just in the brain completely corrected the metabolic disorders that the knockout mice had developed, but also improved the brain cells?ability to respond to leptin signals and produce further signals that regulate eating. What’s more, the mice that were treated to make extra SH2B1 did...Obesity levels in US are grossly underestimated
...ore than women in the same age group. In 2002, the corrected prevalence of obesity in the U.S. population was 2...ted. The research, which presents the first-ever corrected estimates of obesity for individual states, found that Southern states have the highest levels of ob...Brain enzyme treatment relieves memory lapse in Alzheimer's mice
...d memory. Treatments that restored Uch-L1 levels corrected deficits in nerve transmission both in brain slices treated with Aß and in slices taken from transgenic mice with mutations that lead to elevated Aß and associated cognitive decline. The researchers next asked whether Uch-L1 played an important rol...Powerful technique for multiplying adult stem cells may aid therapies
...ish says. With gene therapy, a genetic defect is corrected by administering a healthy version of the gene into a patient. For example, a physician isolates hematopoietic stem cells from a patient, introduces a harmless virus into them that expresses a correct version of the mutated gene, and then re-administ...Chemotherapy gel may fight breast cancer and reduce breast deformity
...ten experience breast deformities that can only be corrected through reconstructive surgery. Researchers at the McGowan Institute for Regenerative Medicine, in collaboration with bioengineers at Carnegie Mellon University, have developed a polymer-based therapy for breast cancer that could serve as an artifici...High fidelity keeps human DNA assembly line humming
...urton's research team also learned ways errors are corrected during rapid RNA synthesis. To learn about error correction, Burton's team stalled the DNA conveyer belt. They did this using a deadly mushroom toxin, alpha-amanitin. Alpha-amanitin is the poison of the death cap mushroom, which can be deadly to hum...Genetic therapy reverses nervous system damage in animal model of inherited human disease
...e show with LAMAN, active enzymes from genetically corrected cells will be secreted into brain tissue and taken...ould increase the amount of enzyme that comes from corrected cells." Although encouraged by their findings, the researchers note that any clinical trials in hum...Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
... glycogen content of heart and skeletal muscle and corrected individual muscle fibers. The effect persisted for...chers reported that the liver-targeted method also corrected symptoms of Pompe disease in mice. "The muscle-targeted gene therapy method could circumvent the co...Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas
...aid. "The impairment was permanent. It couldn't be corrected even when the body caught up to normal weight." Because studies of mice generally are good predictors of human biology, the Joslin study has important implications. "People and their doctors need to understand that prenatal undernourishment makes a ...