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Tag: "core" at biology news

Structure determined for p53 tumor suppressor protein as bound to DNA for anti-cancer activity

...ations in the p53 protein occur in its DNA-binding core domain, pointing to this region of the p53 protein...mple, is that the point of contact between the two core domains of a pair of p53 proteins forming a dimer tracks to a part of the protein often mutated in c...

Arctic coring expedition continues to yield new clues

...itial, shipboard chemical analyses of all the ACEX core samples. "The ACEX cores clearly show that the Arctic got very warm and wet during the PETM," Dickens said. "Even tropical marine plants thrived in the balmy conditions." In today's oceans, certain species of microscopic plants are known to ra...

Hope I die before I get old?

...study data will examine the impact of individuals' core beliefs on their predictions and memory of happiness. Since completing the study, the researchers have gone back to study people between the ages of 40 and 60, and hope to present those data soon. They also plan to study how beliefs about happiness ...

New technology addresses female fertility preservation

...Biological Engineering. "This system establishes a core technology for human egg banks for preservation of fertility." The technology mimics the ovary and its environment. Follicles (each follicle has one egg) from mice were grown in vitro until fully matured by providing the follicles and eggs with the ...

Trials for new drug to overcome HIV

... causing it to form a leaky sphere that leaves the core RNA exposed (see Diagram, left). This cripples the virus, preventing it from infecting any other cells once it buds out from the host. Previous lab experiments on infected human cells have shown that the drug defeats strains of HIV which are resista...

Learning the language of DNA

...regulate their activity. "We have identified the core promoters of the large majority of genes in the mouse and human genomes, expanding the number of known promoters by five- to ten-fold," Professor Hume said. The findings of the consortium have also upended the traditional view that each gene has a ...

Light-sensitive photoswitches could restore sight to those with macular degeneration

... to Isacoff. The nanoscience breakthrough at the core of the research was developed at UC Berkeley and L...being macular degeneration. The chemistry at the core of the photoswitch is a molecule - an azobenzene compound - that changes its shape when illuminated ...

Scientists' cell discovery unearths evolutionary clues

...rity. It also provides a powerful tool to identify core ancestral processes that regulate the most basic aspects of development." Professor Baldauf, of the Department of Biology at York, said: "We have investigated the evolution of plants and animals for a very long time but our whole eco-system depend...

Humpback whales have brain cells also found in humans

... study shows that it is organized into a system of core and belt regions. However, substantial variability was found between the cell structure of the cortex in humpbacks compared to toothed whales. The authors suggest that these differences may indicate differences in brain function and behavior in aquat...

Brains can recover from alcoholic damage but patients should stop drinking as soon as possible

...m the University of Wuerzburg, Germany, said: "The core message from this study is that, for alcoholics, abstinence pays off and enables the brain to regain some substance and to perform better. However, our research also provides evidence that the longer you drink excessively, the more you risk losing th...

Extraordinary life found around deep-sea gas seeps

... beneath limestone boulders and slabs lying at the core of the seeps. Around the rocks were patches of blackened sediment and pockets of white bacterial mats. Most sites also had extensive shell beds consisting of live and dead shells of various types of clams and mussels. These were fringed with stands ...

UCSD researchers discover internal compass of immune cell

... to locate the source of chemoattractants. At the core of the amplification system is the chemical adenosine triphosphate (ATP). The chain of events necessary to direct the neutrophils toward its goal begins when ATP is released from the region of the cell surface closest to the source of chemoattracta...

Small, smaller, smallest -- The plight of the vaquita

... efforts to phase-out fishing with gillnets in the core area of vaquita distribution and to devise schemes involving compensation, incentives and alternative livelihoods for fishermen. For the first time since 1958, when the vaquita was scientifically described and named as a species, the Mexican Gover...

Gene signature assesses breast cancer outcomes

...tumors under 5 cm. The 231 genes were reduced to a core group of 70 that make up a genetic signature to predict outcomes in a separate group of patients from the same institution. To determine whether the 70-gene signature performed better than traditional risk classifiers, scientists from the internatio...

Comments, experts and background on the 2006 Nobel Prize in chemistry

...et of the genetics revolution. It has provided the core technologies that enabled molecular biology and biotechnology to leap ahead. I am delighted that this Nobel Prize highlights chemistry's role in such an important field of research." E. Ann Nalley, Ph.D., is president of the American Chemical Socie...

Tiny Tampa Bay fish key to evolution of immune system

...rticularly those structural features at the stable core of this molecule, then we expect to design and produce more stable monoclonal antibodies for therapy," he said. Neil S. Greenspan, M.D., Ph.D., a professor of pathology at Case Western Reserve University School of Medicine, called the study "captiva...

Scientists crack rhino horn riddle

... shape. The horns of most animals have a bony core covered by a thin sheath of keratin, the same subs...the middle. The calcium deposits make the horn core harder and stronger, and the melanin protects the core from breakdown by the sun's UV rays, the scie...

Novel experiment documents evolution of genome in near-real time

...y because RNA polymerase is involved in one of the core processes of any cell," said Palsson. "You wouldn't expect that gene to change because a wide variety of cellular process would be affected; it's like replacing the wiring system in a building when a light bulb burns out. But we repeated the experime...

Huddling and a drop in metabolism allow penguins to survive the South Pole cold

... decrease during huddling. By contrast, a constant core temperature of 36.9°C was maintained during succes...ful egg incubation and energy savings. The average core temperature measured (36.7°C) was on average 1°C lower than those previously reported for captive em...

Scientists reveal structure of gateways to gene control

...e only ones in the yeast DNA that contain in their core a histone protein called H2A.Z. Led by Pugh and Stephan Schuster, associate professor of biochemistry and molecular biology, the Penn State research team then used antibodies that bind only to this H2A.Z protein as a tool for separating all these pr...

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