No cell walls, no new cancer cells
...ycle. Now we show that the SREBP1 protein actually controls the cell cycle." Senior author, LICR's Dr. Johan Ericsson, realized that disrupting the function of SREBP1 might prevent the lipid synthesis required for new cell walls. "In fact, we literally stopped the cell cycle in its tracks by removing SREBP1...Salk scientists get to the root of plant cell fate
...yonic development, the finding that a co-repressor controls polarity in plants was surprising, says Long. "We thought that because plants and animals are believed to have largely developed independently from each other, they would have used a different set of processes to maintain polarity," he says. "But the...A new view on Lyme disease: Rodents hold the key to annual risk
...k prevention depends in part on understanding what controls infection rates among the agents of transmission. In a new study published in the open access journal PLoS Biology, Richard Ostfeld, Felicia Keesing, and colleagues examined the ecological determinants of Lyme disease over a 13-year period in southea...Gardenia fruit compound starting point for diabetes therapy
...n insulin-producing pancreatic beta cells. Insulin controls blood levels of glucose, the body's main energy source. In those with diabetes, insulin deficiency or insulin resistance causes blood sugar concentrations to rise. The team discovered that Gardenia extract contains the chemical "genipin." Previously...Protein's role in regulating cell death sets direction for cancer research
...ch is a major synthetic structure in the cell that controls the synthesis and distribution of new proteins. In the second study, now published in JBC online, Dr. Greer and co-investigators Yinfei Tan, Chao Wu, and Teresa De Veyra, found that calpain also inhibits programmed cell death in response to other ...Scientists discover that ancient genes dictate flowering, fall bud set
...ts. Surprisingly, we found that this gene not only controls the multi-year delay in flowering in trees, but also controls seasonal growth cessation and bud set," said Nilsson, the corresponding author of the study. The Sw...Important gene controlling tree growth and development found
... control the flowering time of annual plants, also controls tree flowering. With the help of this gene popla...e scientists also show that the same gene not only controls the flowering time of trees, but also the timing of when the trees stop growing and set bud in the f......portant in laboratory studies of the how the brain controls behavior, a field known as neuroethology. Biologi...e place in a relatively simple nervous system that controls behaviors that are easy to study under conditions of neurophysiological experimentation." The obse...Eat less, weigh more? Enzyme makes lean mice 'susceptible' to dietary fat
...ound only in the brain, notably in the region that controls hunger, thirst and metabolism - the hypothalamus. Proteins similar to CPT1c are known to help break down fat to release energy to feed cells. Mice lacking the CPT1c gene are the same length as their littermates who carry normal copies of the gene b...Bacterial 'switch gene' regulates how oceans emit sulfur into atmosphere
... active. Moran and her team discovered a gene that controls whether or not these sea drifters create DMS that rises into the air. "Isolating and discovering a novel, keystone bacterium from the ocean first, and then sequencing its genome enabled this team to find the genes involved in the DMSP cycle," said ...Striking the right balance between excitation and inhibition
...tion of how Notch signaling provides a switch that controls the choice between two different neuronal fates, we can now look and see if it is used in similar ways elsewhere to make different kinds of neurons." The neurons in the dorsal spinal cord analyzed by the Goulding lab form a relay station receiving a...UCSD study reveals how plants respond to elevated carbon dioxide
... how the level of carbon dioxide in the atmosphere controls the opening and closing of leaf stomata--pores through which plants "breathe" in carbon dioxide. The researchers say that their findings provide important insights into the cellular and genetic mechanisms through which increasing carbon dioxide emi...Biotech cotton provides same yield with fewer pesticides
... Protection Agency funded the research. Bt cotton controls only one of Arizona's three major cotton pests. To control the other two pests, sweet potato whitefly (Bemisia tabaci) and the western tarnished plant bug (Lygus hesperus), growers use broad-spectrum insecticides and other types of insecticides known...Key gene controlling eye lens development identified
...elps to better unravel the regulatory pathway that controls normal lens formation," said the paper's senior au...e Six3 gene at the top of the genetic cascade that controls the development of the lens. Understanding the early steps leading to lens formation will help us de...Found -- the apple gene for red
CSIRO researchers have located the gene that controls the colour of apples ?a discovery that may lead to... by light, Adam was able to pinpoint the gene that controls the formation of anthocyanins in apples, and we found that in green apples this gene is not expresse...High dopamine transporter levels not correlated with ADHD
...age, five times greater for ADHD subjects than for controls in this study. "These findings suggest that an additional variable in conjunction with dopamine transporters would be required to account for the severity of the symptoms of inattention in ADHD," Volkow said. "We speculate that this other variable ...Electronic chip, interacting with the brain, modifies pathways for controlling movement
...ew nerve connections in the part of the brain that controls movement. Their most recent study, to be published in the Nov. 2, 2006, edition of Nature, showed such a device can induce brain changes in monkeys lasting more than a week. Strengthening of weak connections through this mechanism may have potential ...Molecular 'on/off switch' controls immune defenses against viruses
...have found. This same molecular "on/off switch" controls immunity against many viruses, highlighting a pote...in a repressor domain, a sort of docking site that controls the actions of each protein. The domain is the key site that regulates the ability of RIG-I to bind ...New biologic treatment for tennis elbow may replace surgery for chronic sufferers
... a degeneration of the tendon above the elbow that controls the movements of the wrist and hand. Treatments such as rest, nonsteroidal anti-inflammatory drugs, bracing, physical therapy, and injections of corticosteroids (cortisone shots) are often used but recent studies have called into question their effi...Chemotherapy temporarily affects the structures of the human brain
... consistent in the long-term. In addition, lack of controls in studies makes it difficult discern cancer- vers...no differences between cancer patients and healthy controls at any time point demonstrates that there is no observable cancer-effect in cognitive deficits. T...