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Tag: "controlling" at biology news

Gene silencing technique offers new strategy for treating, curing disease

A new technique aimed at directly controlling the expression of genes by turning them on or off ...nt techniques for turning genes on or off focus on controlling the messenger RNA once it's already produced. But blocking all the copies of messenger RNA before th...

Discovery of New Dopamine Action May Yield Alternative Psychiatric Drugs

...r potential new inhibitors that might be better at controlling particular psychotic behaviors." Caron is a professor of cell biology at Duke and faculty member at the Duke Institute for Genome Sciences & Policy. Dopamine's prolonged effects might also apply to understanding the impact of sustained drug use ...

Protein synthesis can be controlled by light, opening way for new scientific, medical applications

...s, among many others, researchers want to know the controlling mechanisms for how these cells are chosen for their specific roles. "If we had a way to selectively abolish protein synthesis in subcellular compartments and observe the effects, then we could infer the role of local protein synthesis in development...

The making and breaking of microtubules

...egulate enzyme activity and play a crucial role in controlling microtubule growth. When GTP binds to a particular locus on beta tubulin (the E-site or exchangeable site) polymerization occurs: tubulin dimers pile onto the protofilaments, and the microtubule grows. But through hydrolysis (the word means "water s...

UNC plant researchers discover proteins interact to form hair-trigger protection against invaders

...ate response to bacteria and other attackers. "By controlling disappearance of resisting proteins, RAR1, HSP90 and SGT1 control whether or not the plant is about to recognize that it is under pathogen attack," Holt said. "So the emerging story is that RAR1 and HSP90 keep resistance proteins ready to perceive pa...

FDA approves more generic AIDS drugs

...ate response to bacteria and other attackers. "By controlling disappearance of resisting proteins, RAR1, HSP90 and SGT1 control whether or not the plant is about to recognize that it is under pathogen attack," Holt said. "So the emerging story is that RAR1 and HSP90 keep resistance proteins ready to perceive pa...

Major breakthrough in the treatment of cancers and infectious diseases

...ette's team identified one of the basic mechanisms controlling NK ("natural killer") cell activity. Produced by t... in the identification of the molecular mechanisms controlling the immune system. The article, which is slated for publication online on August 28 in Nature Immuno...

Male Combat Veterans Rank High In Heart Disease Risk

...erm adverse effects on cardiovascular risk. After controlling for age, race and education, the study found that combat veterans were 1.9 times more likely to be heavy smokers as opposed to never smokers than non-veterans and 1.2 times more likely to be heavy smokers as opposed to never smokers than non-combat v...

Going To Extremes To Improve Human Health

...t point between 14 and 122 degrees Fahrenheit, and controlling humidity anywhere from 10 to 95 percent. The chamber is so finely tuned that it can swing from the coldest to hottest setting in 30 minutes. "The presence of the environmental chamber at the University of Oregon will assure the next generation of re...

Attacks of King George III's madness linked to key metabolism molecule

...me manufacture in the liver. One of its actions is controlling the activity of the ALAS-1 gene that makes a prote... "We found that PGC-1 alpha is an important factor controlling the expression of ALAS-1 in the fasted and fed liver," the authors write. "Moreover, we showed that ...

Scientists find that protein controls aging by controlling insulin

...ed that a protein prolonging life in mice works by controlling insulin. The protein, Klotho, is found in several species. In mice, the researchers discovered, it acts as a hormone, circulating through the blood and binding to cells. Therapies based on this hormone could prove to be a way to extend life or slo...

VCU study shows hormone-like molecule kills cells that cause inflammation in allergic disease

...uch as interferon gamma, are an important means of controlling mast cell function in the body," said John J. Ryan, Ph.D., associate professor of biology at VCU and lead author of the study. "Because mast cells cause inflammation, regulating how many mast cells the body makes, where they go, what they do, and whe...

Climate model links higher temperatures to prehistoric extinction

...uch as interferon gamma, are an important means of controlling mast cell function in the body," said John J. Ryan, Ph.D., associate professor of biology at VCU and lead author of the study. "Because mast cells cause inflammation, regulating how many mast cells the body makes, where they go, what they do, and whe...

University of Nevada, Reno research team discovers hormone that causes malaria mosquito to urinate

..., could lead to the development of a pesticide for controlling mosquitoes. "Synthetic compounds that mimic the action of these peptide hormones should be useful as pesticides," Schooley said. "Like methoprene, DH31 only affects lower species such as insects, which suggests it should be very safe to non-insect s...

Say what? Bacterial conversation stoppers

...ow many neighbors they have and, in turn, properly controlling its behavior." "This study moves us closer to really understanding how these interactions happen in nature," Bassler said. "Bacteria can communicate between species, and they have evolved mechanisms to interfere with the communication. Probably this...

Space matters: Estimating species diversity in the fossil record

... relies on descriptions of past extinction events, controlling for a paleodiversity¡Varea effect may provide a better frame of reference for understanding the current biodiversity crisis. Thanks to the innovative text-mining tools and approach presented here, future studies can more easily correct for area effec...

Woods Hole Research Center plans controlled burn in Amazon rainforest

...tion, local firefighters will be present to aid in controlling the fire and also to use the opportunity to train with actual forest fires. Collaborators at Stanford University are collecting satellite data prior to and after the burn for each of the 3 parcels, to compare the appearance of the forest before and a...

Investigating 'brain shrinkage' in alcoholics

...e samples from these regions and look at the genes controlling structure and function and even identify individual proteins that might play a role in cognitive deficits as well as recovery and repair of the brain. Together we can develop strategies for public education and new approaches to therapy in people who...

Gene therapy to lower blood pressure just enough

... low levels, said O'Malley. Obviously, a method of controlling the gene and the amount of ANP a cell makes was needed. The special viral vector developed by O'Malley and his colleagues combines a special kind of adenovirus altered so it does not produce disease connected to a gene regulatory system turned on by...

Gene controlling circadian rhythms linked to drug addiction

...ne than control mice did, suggesting that the gene controlling circadian rhythms is a key regulator of the brain's reward system and may influence the addictive properties of drugs such as cocaine. "We tracked dopamine cells in the mice brains and found that these cells fired more rapidly and showed a pattern c...

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