Some Brain Cells 'Change Channels' To Fine-tune The Message
...s been recognized for a few years, the key players controlling it hadn't been identified. Now, by studying mice, the Hopkins team has identified two proteins, called PICK1 and NSF for short, that help replace channels that let charged calcium ions in with another kind of channel that keeps calcium out. If muscle...Used in a new way, RNA interference permanently silences key breast cancer gene
...de normal tissues like the lung. "Somehow STAT3 is controlling TWIST expression, and this is important to know with regards to activated STAT3 and its involvement in cancer metastasis," Arlinghaus says. When the mouse breast cells transduced with STAT3, shRNA were then tested in immunocompetent mice, researcher...Brain-injury rehabilitation depends on acetylcholine circuitry
... lesions in the rats' brain region responsible for controlling limb movement. They then gave the rats rehabilitation training. The control group of rats recovered about 55% of the deficit in their reaching ability, while the rats lacking a cholinergic system recovered only about 18%. In other experiments, the ...Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression
...ther animals have evolved many overlapping ways of controlling gene expression. Many different controls determine when a DNA gene is transcribed into mRNA, and when and how the mRNA is translated into a protein. Many proteins are also tightly controlled through various post-translational modifications that activ...Maine Researchers Find Exceptions to Old Rules of Genetic Inheritance
...cientists realized, two genes must be involved-one controlling sterility and a yet-to-be discovered gene regulating transmission ratio distortion. Dr. Planchart commented, "For more than 50 years, researchers have sought the biochemical and molecular basis of these phenomena. This work represents a landmark stu...One gene links newborn neurons with those that die in diseases such as Alzheimer's
...tory has pioneered the study of the brain pathways controlling how songbirds learn to sing. A discrete region of the brains of songbirds, known as the high vocal center, controls their singing behavior. It was in this brain region that, more than 20 years ago, Nottebohm discovered new neurons being born in adult...Master gene controls healing of skin in fruit flies and mammals
...colleagues have discovered that the genetic system controlling the development and repair of insect cuticle--the outer layer of the body surface in insects--also controls these processes in mammalian skin, a finding that could lead to new insights into the healing of wounds and treatment of cancer. The UCSD bio...Stealth Worms May Improve Insect Pest Control
...to provide an environmentally safe alternative for controlling insect pests in agricultural and forestry systems, and also for controlling insect pests of human and veterinary importance," Stock says. In each location the scientists start...Researchers find gene that may be at root of potato blight
...the pathogen that causes late blight. For decades, controlling this disease has involved regular applications of agrochemicals, Kamoun said. But some experts fear that the pathogen is making a comeback. "Given the recent widespread occurrence of new fungicide-resistant strains of this pathogen, it could be con...WHO suspends Marburg work, appeals for new funds
...can countries, the single most important factor in controlling viral haemorrhagic fevers is the engagement of affected communities as partners in control. To achieve this engagement, local belief systems about the causes of disease and traditional rituals for mourning the dead must be respected. When the public ...UN environmental agency steps up battle against marine pollution
...ironmental agency and an international treaty body controlling hazardous wastes. The Memorandum of Understanding, signed last week in Nairobi, Kenya, by the UN Environment Programme (UNEP) Regional Seas Programme and the Secretariat of the Basel Convention on the Control of Transboundary Movements of Hazardous W...How A Latent Virus Eludes Immune Defenses
...rs, scientists can identify a promising target for controlling infection. Copyright: © 2005 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided th...Touching Molecules With Your Bare Hands
...rs, scientists can identify a promising target for controlling infection. Copyright: © 2005 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided th...Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage
...ear importance in resisting disease, the processes controlling the generation of gamma-delta T cells have remained mysterious until recently. As Robert Frost put it, Wiest pointed out: "Two roads diverged in a wood, and I-- I took the one less traveled by, And that has made all the difference." "Gamma-delta T c...NHGRI targets 12 more organisms for genome sequencing
... which lay their eggs on and kill arthropods, thus controlling pest populations. In the United States, the use of parasitoid wasps in agriculture as a biological control of crop damaging insects saves approximately $20 billion annually. The wasp will serve as a good comparison for the honey bee genome, which has...Pair of cancer genes found to drive both cell migration and division
...es of the two genes in dividing cells by seeing if controlling the location of the PTEN and PI3K proteins can determine the direction in which cells divide, Devreotes says. ...Some Brain Cells Change Channels
...s been recognized for a few years, the key players controlling it hadn't been identified. Now, by studying mice, the Hopkins team has identified two proteins, called PICK1 and NSF for short, that help replace channels that let charged calcium ions in with another kind of channel that keeps calcium out. If muscle...Scientists find viruses can't stick to sea bugs in the dark
...t may also eventually lead to efficient methods of controlling cyanobacteria blooms in an environmentally friendly way, by using these natural viruses. ...New miniaturised chip dramatically reduces time taken for DNA analysis
...rrent into a signal that can be seen by the person controlling the tests, making him aware there are bacteria. Also, because the sensors are very small and easy to manipulate, it is possible to assemble a set of sensors that can collect data simultaneously and deduce information about the bacteria such as which ...Understanding how bacteria communicate may help scientists prevent disease
...hey remain harmless, is an alternative strategy to controlling disease," he said. Kulkarni will continue his collaboration with the Princeton University group on V. cholerae and will collaborate with Virginia Tech Biology Professor Ann Stevens, whose group is working on V. fischeri, the bacteria that causes lum...