New lead reported in tumor angiogenesis
... conducted a series of experiments under carefully controlled laboratory conditions to determine whether, as they suspected, HGF stimulates head and neck tumor cells to release pro-angiogenic proteins. To their surprise, they found that was not the case. Tumor cells stimulated by HGF strongly promoted the forma...Gene therapy to lower blood pressure just enough
...ses of drug turned on the regulatory system, which controlled the amount of ANP made so that blood pressure remained at healthy levels for 125 days - 74 days longer than in any previous gene therapy study. Other studies indicate that the therapy could reduce the heart-weight/body-weight ratio. For this reason i...Chemical 'band-aid' prevents heart failure in mice with muscular dystrophy
... a rubber band," Yasuda says. "You can do specific controlled stretches and record the force generated by the cell. We found that myocytes from normal mice easily handled a 20 percent stretch in length, while myocytes from dystrophin-deficient or mdx mice had about 70 percent more passive tension in response to...How cell suicide protects plants from infection
...lants fend off microbial attacks through carefully controlled destruction of infected cells," said James Anderson, of the Division of Genetics and Developmental Biology at the National Institute of General Medical Sciences (NIGMS). "Like other studies carried out in model organisms, these findings shed light on...Device traps, disables harmful bacteria
...so tested the hybrid filters in an environmentally controlled laboratory chamber to come up with the air-exchange rate for the therapy pool assays, among other parameters. The researchers published their results in the Feb. 2005 issue of the Journal of Air & Waste Management Association. The study was supp...Hormones and growth: The control of body size and developmental growth rate in fruit flies
...isms by which body size and developmental rate are controlled remain incompletely understood. Both studies examine the control of larval development in the fruit fly Drosophila. Fruit flies undergo three successive larval stages and molts before undergoing metaphorphosis and emerging as adult flies. In insects...Insight into our sight: A new view on the evolution of the eye lens
...y, expression of the sea squirt crystallin gene is controlled by genetic elements that also respond to the factors that control lens development in vertebrates: The researchers showed that when regulatory regions of the sea squirt gene are transferred to frog embryos, these regulatory elements drive gene expres......esearch also has shown that gene expression can be controlled by several regulatory proteins working together at a combination of different binding sites. (Regulatory proteins are known as "transcription factors"; transcription is the first step in the process by which the genetic information in DNA is decoded...Bleach found to neutralize mold allergens
...c health effects. "This study was conducted under controlled laboratory conditions. In order to assure that the bleach solutions will function similarly under actual field conditions, additional experiments will need to be conducted," said Dr. Martyny. "We do believe, however, that there is good evidence that...Old drug, new tricks: Prospects for slashing the impact of malaria
...ucture already exists to dispense the tablets in a controlled way, since PNG's children routinely attend clinics to be vaccinated against a range of other diseases. The project funding allows significant expansion of joint activities and research among the collaborating institutions. Successful completion o...Once given 'no respect,' cells' tiny RNAS take driver's seat
...tissues, but no one had been able to identify what controlled the timing," says Joshua Mendell, M.D., Ph.D., ass...controls the expression of genes. One of the genes controlled by E2F1 just happens to be the gene for Myc. "This establishes a feedback loop," says Kathryn O'Don...Digging in the dirt for life's biochemical foundations
...e researchers demonstrated the results in a highly controlled laboratory environment, so "the big challenge now will be to see whether the same mechanism is important for entire plants growing in symbiosis [partnership] with the fungi in soil, where other nitrogen sources may be more easily available," Fitter s...Vineyard weeds found to host Pierce's disease of grapes
...se," Wistrom said. "Currently, Pierce's disease is controlled by reducing populations of the insect vector, either through insecticide sprays or habitat modification to remove insect breeding host plants. Our study reinforces the need for weed control in irrigation ditches and roadsides adjacent to vineyards, i...Geckos: It's not always about sex
...ab at Lewis & Clark, the researchers precisely controlled the lizard's speed, body temperature, and measured how much energy the four-footers used to walk. Wahl, an alumna of Lewis & Clark, is now a doctoral student in wildlife biology at the University of Montana at Missoula. "We found that the parthe...Sugar helps control cell division
...ecades has been that the cycle of cell division is controlled by the appearance and disappearance of certain proteins called cyclins, but experiments have shown that you can knock out any of these and still get perfectly normal cell division," says the study's first author, Chad Slawson, Ph.D., a postdoctoral f...Scientists uncover new clues about brain function in human behavior
...nstitutes of Health, have discovered a genetically controlled brain mechanism responsible for social behavior in humans--one of the most important but least understood aspects of human nature. The findings are reported in Nature Neuroscience, published online on July 10, 2005. The study compared the brains of ...Scientists create digital bacteria to forge advances in biomedical research
...ations, Emonet discovered that one type of protein controlled the sensitivity of E. coli's chemotaxis system, which helps the bacteria find food. "When you changed the level of that protein, it would change the sensitivity of the cell," Emonet said. Subsequent laboratory experiments came out exactly the same wa...Long-sought flower-inducing molecule found
... This gene is active in leaves and its activity is controlled by the length of the day. When the gene is activated, a messenger molecule is produced that is transported to the shoot tips where it very efficiently induces the "gene programs" that control the formation of flowers. These groundbreaking results are...'Cookbook recipes' would cure disease with nontoxic DNA delivery systems
...ions -- a feature that could prove useful in other controlled drug delivery applications. The researchers also produced inverted hexagonal structures with encapsulated DNA. "First, the strands of DNA are coated with positively charged ions," Wong said. "The strands are then wrapped with negatively charged lipi...Forsyth scientists find three bacteria associated with oral cancer
...The scientists obtained similar findings when they controlled for gender, age, and smoking history. According to Mager, "Those results led us to hypothesize that the three species could serve as diagnostic indicators for OSCC. And, in fact, we found that elevated salivary counts of the three bacteria correctly...