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Tag: "control" at biology news

UCSD-Salk Team Show Protein’s Gene-Silencing Role In Development of Nervous System

...r gene complex called REST/NRSF, which is known to control neuronal genes. In their investigations with mice and fruit flies, the scientists found that REST/NRSF recruits SCPs only to neuronal genes. “These findings suggest a way to expand the pool of neuronal stem cells, which could lead to new therapeuti...

Scientists identify molecule that regulates well-known tumor suppressor

...gulates PTEN function, and that this cell survival control mechanism is conserved among various tissues and species. Taken together, our data suggest that overexpression of DJ-1 can modulate PTEN tumor expression to the point where oncogenesis may result from upregulated PKB/Akt-mediated cell survival," writ...

Anti cancer virotherapy well tolerated in first human administration, research finds

...therapy based on the use of a common cold virus to control cancer cell growth has begun safety testing in human subjects. The research was presented to the third International Meeting on Replicating Oncolytic Virus Therapeutics, on Friday 11 March by Newcastle University associate professor, Darren Shafren....

Love's all in the brain: fMRI study shows strong, lateralized reward, not sex, drive

...dy. These regions were significant compared to two control conditions, providing strong evidence that these brain areas, which are associated with the motivation to win rewards, are central to the experience of being in love." Brown noted that "an important concept is that the caudate probably integrates hu...

To control germs, scientists deploy tiny agents provocateurs

... thwart persistent bacterial infections and better control group behaviors of certain microorganisms, scienti...s in bacterial cells, Blackwell aims to ultimately control the formation of biofilms, goo-like amalgamations of bacteria that are widespread in nature and have...

Scientists identify genetic pathways essential to RNA interference

...ccurs naturally in plants and animals and may help control resistance to viral infection, among other functio...ggests a potential connection between RNAi and the control of cell division in cancer." The researchers note that better understanding the mechanisms underlyi...

Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis

...cl-1 gene. This was an important clue to how cells control the powerful effects of Mcl-1. Other authors of this study are Hiromi Iwasaki, Christy C. Ong, Heikyung Suh, Shin-ichi Mizuno, Koichi Akashi and Stanley J. Korsmeyer (Dana-Farber Cancer Institute). ...

New Estimates For The Causes Of Child Deaths Worldwide

...rate will depend on renewed efforts to prevent and control pneumonia, diarrhoea, and undernutrition in all WHO regions, and malaria in the Africa region. In all regions, deaths in the neonatal period, primarily due to preterm delivery, sepsis or pneumonia, and birth asphyxia should also be addressed. The new...

Yeast Network Prevents Damage By Oxygen Radicals

...ntified a key network of DNA repair and cell cycle control genes in yeast that prevents the deleterious effects of ROS. "DNA repair and cell cycle control mechanisms are important guardians against cancerous changes in human cells," says Dr. Richard Kolod...

White Blood Cell 'Waste Disposal' System Plays Critical Regulatory Role

...ction. A clear understanding of the processes that control neutrophil turnover may contribute to the development of future therapeutics for conditions characterized by abnormal numbers of these critical immune cells. Human neutrophils are white blood cells that are constantly being produced in the bone marr...

Mystery Blood Vessel Disorder Implicated In 'Mini' Strokes

...es can impair functions such as movement, physical control of speech, or coordination. Multiple lacunar strokes can also cause cognitive and memory deficits that resemble Alzheimer's disease. According to the authors, physicians who encounter patients with small vessel disease should look for evidence of do...

Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment

...es for vitrified eggs are similar to the rates for control eggs that were not vitrified. For egg freezing to work, it must be a mature oocyte, which means a woman must have 14 days of hormone treatments to stimulate mature egg production. This could limit its applications for some women. Researchers questio...

Canada approves marijuana-based pain spray

... assessment for the approved use. “Effective pain control and management are extremely important in a diseas...allows for flexible dosing and puts the patient in control of their pain,?said Dr. Gordon. “This is very important since pain severity varies between different...

Shift of weather patterns necessitates rethinking of reforestation methods

...ularly considering the landowner doesn't have full control over all factors with bare root seedlings, he said. The trees may arrive at the site already stressed. "And this is a big factor in their survival," Taylor said. Another big factor is the subjection of new to hot dry conditions before they've had a...

New understanding of DNA repair may pave way to cancer treatments

...2's role in regulating expression of proteins that control cell cycle and programmed cell death is well established. The current study is the first to demonstrate ATF2's role in DNA repair, an intracellular process that prevents formation of genetic mutations, including those that lead to cancer. "This is t...

Live vaccines more effective against horse herpes virus

...inated with the inactivated virus and one from the control group showed mild neurological symptoms. All the horses, however, have fully recovered. Osterrieder decided to announce the results of the study prior to peer-reviewed publication because of the recent virus outbreaks. Following the outbreak at Chur...

Brain-injury rehabilitation depends on acetylcholine circuitry

... representations"--to reestablish connections that control muscles. However, the specific type of brain circu... sensory regions of the animals' cortex. The other control group received a sham injection. The researchers then used electrical probes to create small lesions...

New tumor-suppressor gene discovered

...ow the gene works with another tumor suppressor to control tissue growth. The team's genetic and biochemical studies will be published in the 11 March 2005 issue of the journal Cell. "This discovery extends our understanding of how tissue growth is controlled both during normal development and during the for...

Grasping metaphors: UC San Diego research ties brain area to figures of speech

...rformed at the level of chance. Three age-matched control subjects, on the other hand, with lesions in other areas of the brain, performed normally both with proverbs and the booba/kiki test. Disproportionately larger in hominids than other primates, the angular gyrus, given its strategic location at the c...

Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression

...ability of these mRNA transcripts is essential for control of genetic expression. In the latest issue of the...ology Professor Jiahuai Han, describes how genetic control can be exerted in living cells through microRNA's action in conjunction with several different prote...

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