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Tag: "contribute" at biology news

Search on for treatment of slow-healing wounds

...cer that won't heal. For diabetics, such wounds contribute to a foot or lower-leg amputation rate 10 to 15 times higher than non-diabetics. Eighty percent of diabetics who underwent amputation for chronic wounds died within five years, according to a Finnish study. The incidence of chronic wounds in the U...

Age-related changes in DNA repair illuminate the connection between age and genetic damage

...s of DNA repair used by cells of young individuals contribute to the accumulation of genetic damage, and perhaps to the aging process itself. Older cells may use the safer repair methods, but they still carry the genetic damage incurred during DNA repair in the fly's "reckless" youth. ...

Sunflower speciation highlights roles for transposable elements in evolution

...urthers our understanding of how hybridization may contribute to genome changes and the evolution of new species, researchers have found that the genomes of three sunflower species that arose in evolution as hybrids of the same two parental types have undergone a massive proliferation of genetic entities known ...

St. Jude finds clues to hearing loss from chemotherapy

...dentified the various problems in the ear that can contribute to hearing loss in these models, we can work back and look for specific mutations in these animals," Zuo said. "That will let us link specific mutations to specific disruptions in the ear that cause hearing loss. The long-term goal is to try to manip...

How many genes does it take to learn? Lessons from sea slugs

...clusters of genes within an untold amount of cells contribute to major neural events. "For the first time we provide a genomic dissection of the memory-forming network," said Leonid Moroz, a professor of neuroscience and zoology at the University of Florida Whitney Laboratory for Marine Bioscience. "We took...

A new jump start for aging blood vessels

...s, demonstrating that increased TNFa levels likely contribute to age-related cardiovascular disease. Similar cell-protective effects were found when anti-TNFa antibodies were used in cell culture. Third, not only was TNFa released into the blood, where it can have systemic effects, but it is also expressed...

Cell wall of pneumonia bacteria can cause brain and heart damage

...archers have also shown how antibiotic therapy can contribute to this damage by increasing the number of cell wall pieces shed by dying bacteria. The team also demonstrated in a mouse model how to prevent this from happening. The study shows that pieces of cell walls from Streptococcus pneumoniae bacteria "hij...

Scientists work to identify genes that contribute to early heart attack risk

...illion multi-year study to identify genes that may contribute to early atherosclerosis. "If we can identify pe...dult life. Doctors have known that genetic factors contribute to risk for early atherosclerosis but the exact genes involved are not yet known. "We hope the S...

Scientists solve 30-year-old mystery of mutant mouse's kidney woes

...ect a variety of environmental and genetic factors contribute to fetal hydronephrosis. However, they frequently ...lab also is looking for other genetic factors that contribute to renal diseases. ...

Master planners in brain may coordinate other areas' roles in cognitive tasks

...o be helping to determine which brain regions will contribute to a cognitive task and when those regions will pl...s of the brain have specialized abilities that can contribute in various ways to completion of different tasks. They just have to be lined up to play their part w...

Tastes great! Study shows brain's response to pleasing -- and changing -- tastes

...ns go wrong in ventral pallidum, it could possibly contribute to eating disorders, anorexia and drug addiction. Eventually, activation in the ventral pallidum in response to pleasurable tastes could also be useful in brain-mapping techniques in humans. All in all, Aldridge says, the new paper is "a really go...

Gut reaction: Researchers define the colon's genome

...d, in the case of humans, how microbial ecosystems contribute to health and disease. "This study is an important first step toward identifying microbial differences between healthy people and those with conditions ranging from Crohn's Disease to cancer," says co-author Karen Nelson of TIGR, who has previously...

Epstein-Barr virus might kick-start multiple sclerosis

...rus. The virus, which causes mononucleosis and may contribute to some cancers, has long been suspected to play a role in MS. However, the mechanism linking the virus to the disease was poorly understood. Scientists think that MS--which can cause vision problems, muscle weakness, and difficulty with coordinati...

New angiogenesis finding may help fight cancer growth

...Maybe excess levels of NK-B are responsible for or contribute to impaired vascular development/function and certain symptoms of preeclampsia." According to the Preeclampsia Foundation, the condition affects about 200,000 American women each year. Many angiogenesis inhibitors are under study at this point, b...

Mouse study reveals new clues about virulence of 1918 influenza virus

...us triggers a hyperactive immune response that may contribute to the lethality of the virus. Furthermore, their results suggest that it is the combination of all eight of the 1918 flu virus genes interacting synergistically that accounts for the exceptional virulence of this virus. Michael G. Katze, Ph.D., o...

Free radical cell death switch identified

...tive stress in neurons and other cells in the body contribute to tissue damage in a variety of disorders, including stroke, ischemic heart disease, neurodegenerative diseases, and diabetes, identification of the MST-FOXO switch mechanism could provide potential new targets for the diagnosis and treatment of man...

New study reveals structure of E. coli multidrug transporter protein

...residues in the EmrD internal cavity are likely to contribute to the general mechanism transporting various compounds through the cell membrane, and may play "an important role in dictating a level of drug specificity" through a number of molecular interactions. The study also suggests that EmrD intercepts ...

A new kind of mutation could explain numerous phenotypic variations in various species

...f mutation, discovered while studying sheep, could contribute significantly to the phenotypic variation observed in many species ?among which humans ?including the hereditary predisposition to various diseases. Researchers at ULg have thus produced a database available online that compiles all these mutations ...

Protein's role in regulating cell death sets direction for cancer research

...osits, this might seem like a bad thing that could contribute to neurodegenerative disease," says Dr. Greer who produced the study with Yinfei Tan, Nathalie Dourdin, Chao Wu, Teresa De Veyra, and John S. Elce. "On the other hand, when a cell's chromosomes are damaged by carcinogens or ultraviolet light in a wa...

Origen publishes in Nature a robust and versatile method for creating transgenic chickens

...ro to differentiate into embryonic germ cells that contribute to somatic tissue. "As well as the practical applications of this work, the ability to engineer PGCs and influence them to commit in cell culture to either the germline or the somatic lineages provides a very useful new tool for understanding some o...

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