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Cellular message movement captured on video

...in that binds to paxillin and that interaction may contribute to the carcinogenic potential of the sexually transmitted virus. Chien and Hu obtained cells for their most recent study from the inner membranous lining of a cow aorta. They added genetically engineered proteins tagged with red and green fluoresc...

Researchers discover inherited mutation for leukemia

...ndings also provide evidence that some genes might contribute to cancer even when they are not silenced entirely. "This inherited change is remarkably subtle," says co-principal investigator Albert de la Chapelle, professor of molecular virology, immunology and medical genetics and a researcher with the Ohi...

Gene therapy delivery of nerve growth factors reverses erectile dysfunction in animal model

...th promoter and has been shown in other studies to contribute to survival and regeneration of penile nerves. Neurturin also is a nerve growth factor closely related to GDNF. Control mice received only the virus without the GDNF or neurterin genes inserted. Four weeks after the treatment, rats administered H...

Snoring in children might be an allergic type disease

... allergy and inflammation”. “Our data hopefully contribute to a clinician’s ability to effectively spot snoring in pre-school children in order to identify potentially more serious obstructive sleep apnoea.” ...

A new plant-bacterial symbiotic mechanism promising for crop applications

... living in symbiotic association with bacteria can contribute to vegetation regeneration schemes on soils depleted in nitrogen owing to overexploitation, erosion or desertification. The plant cover thus formed can help achieve ecological restoration, by enriching the soils in nitrogen. However, the symbiotic pr...

Research team identifies new Alzheimer's gene

...ith the genome-wide genetics studies to come, will contribute to the clarification of Alzheimer’s risk factors and disease mechanisms, the discovery of promising new disease-slowing and prevention therapies, and the identification of patients and at-risk people most likely to benefit from those treatments,” sai...

Loss of stem cells correlates with premature aging in animal study

...an overwhelming amount of DNA damage and could not contribute to tissue renewal; nevertheless, the 10 to 20 percent of cells that escaped ATR deletion were able to reconstitute tissues in the engineered mice, at least initially. “Think of aging as a slow loss of stem cells, a deterioration of pools of cell...

New study finds genetically engineered crops could play a role in sustainable agriculture

Genetically modified (GM) crops may contribute to increased productivity in sustainable agriculture, according to a groundbreaking study published in the June 8 issue of the journal Science. The study analyzes, for the first time, environmental impact data from field experiments all over the wor...

Sun exposure early in life linked to specific skin cancer gene mutation

...erent gene mutations, but just how these mutations contribute to the cause of melanomas has been a mystery. A new clue comes from scientists at the University of North Carolina at Chapel Hill Schools of Medicine and Public Health. Their research indicates that early life sun exposure, from birth to 20 years ol...

Researchers reveal structure of protein altered in autism

...rticular genetic mutations affect this complex and contribute to the developmental abnormalities found in children with autism. Their work, published as the cover article in the June issue of the journal Structure, should help scientists pinpoint the consequences of other genetic abnormalities associated with t...

New findings challenge established views on human genome

...part and understand how the parts work together to contribute to health and disease. In recent years, researchers have made major strides in using DNA sequence data to identify genes, which are traditionally defined as the parts of the genome that code for proteins. The protein-coding component of these gen...

Surprising origin of cell's internal highways

...bule regulation of migration and invasion probably contribute to the therapeutic effects." Therefore, further study of this new subset of microtubules might offer insight into how the invasion of cancer cells into surrounding tissues could be halted. ...

Male circumcision overstated as prevention tool against AIDS

...amy in these Muslim communities does not appear to contribute to hi gher AIDS prevalence as previously speculated. In a frequently cited academic paper, Daniel Halperin, an H.I.V. specialist at the Harvard Center for Population and Development and one of the world’s leading advocates for male circumcision, weig...

St. Jude study shows genes play an unexpected role in their own activation

... mechanism; and that each mechanism may or may not contribute equally to activating a specific gene. The team also found evidence that other proteins can act as back-up co-factors for CBP/p300. “This more complex view of how CREB works may help us understand how this single transcription factor can stimulate...

Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism

... atherosclerotic process. Moreover, these findings contribute to the design of novel preventive and therapeutic strategies....

For many insects, winter survival is in the genes

..., the findings broaden our palette of players that contribute to cold tolerance in insects." He said the next step is to figure out the unique functions of each heat-shock protein. "We assume it's not simply redundancy in the system, but that each protein makes a unique contribution somehow," Denlinger sa...

Detecting cold, feeling pain: Study reveals why menthol feels fresh

...matory and nerve injury, and how these changes may contribute to chronic pain," says senior author David Julius, PhD, chairman and professor of physiology at UCSF. The methanol receptor, and other temperature receptors discovered in recent years by the Julius lab, offer potential targets for developing anal...

Pistachios lower cholesterol, provide antioxidants

...ts. It is oxidized LDL and other lipproteins that contribute to plaque formation in arteries. The researchers reported that both the 1.5 and 3 ounce pistachio diets reduced oxidized LDL compared with the baseline diet. Pistachio-enriched diets also resulted in significantly higher levels of lutein in the b...

Early exposure to indoor fungus molecules may protect infants against future allergies

...teins. Some fungi also contain mycotoxins that can contribute to disease," adds Tiina Reponen, PhD, professor of environmental health and corresponding author of the study. "Exposure to indoor molds during infancy may be associated with respiratory symptoms, such as persistent coughing and wheezing." The UC-...

Puzzling plankton yield secrets to role in evolution/global photosynthesis

...s ever characterized, barely a micron in diameter, contribute to a significant share of the world’s total photosynthetic activity. These "picophytoplankton" also exhibit great diversity that contrasts sharply with the dearth of ecological niches available to them in aquatic ecosystems. This observation, known a...

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