Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
...ted high levels of the enzyme and reduced glycogen content in the injected muscle. The mice also had a reduce...n of the muscle-targeted gene reduced the glycogen content of heart and skeletal muscle and corrected individual muscle fibers. The effect persisted for 24 wee...The BIOS Initiative - open source biotechnology is born
...owing patenting of products, where necessary. Not content with inventing new technology and new software communities, CAMBIA is also releasing new functionalities in its highly successful Patent Lens, which includes the world's fastest free, full-text searchable patent database, with over 1.6 million patent...Applied Biosystems Introduces Advanced Gene Expression Service Provider Program
...in genetic analysis using interpretation tools and content to advance scientific research while helping them achieve necessary return on investment, was announced today in advance of this weekend’s annual World Microarray Congress in Vancouver, Canada. The Applied Biosystems Expression Array System forms th...Sequencing of marine bacterium will help study of cell communication
...hogenic Vibrio species. V. fischeri has a lower GC content than other sequenced Vibrio species, but it is still more closely related to them than other organisms. (Among the four nucleotides that make up DNA ?adenine, guanine, thymine, and cytosine (ATGC) ?'A' pairs with 'T' and 'G' pairs with 'C'. The more ...Harnessing microbes, one by one, to build a better nanoworld
...in genetic analysis using interpretation tools and content to advance scientific research while helping them achieve necessary return on investment, was announced today in advance of this weekend’s annual World Microarray Congress in Vancouver, Canada. The Applied Biosystems Expression Array System forms th...Opposing fat metabolism pathways triggered by a single gene
... gonad. This was accompanied by unusually high fat content in the larvae. They further showed that deletion of nhr-49 changed expression of 13 genes related to fat and glucose metabolism, with the most dramatic effects occurring within two metabolic pathways: mitochondrial lipid oxidation and fatty acid desa...Children's taste sensitivity and food choices influenced by taste gene
...eals and beverages of PP children had higher sugar content than corresponding selections of AA children. According to study co-author, geneticist Danielle Reed, PhD, "The children most sensitive to PROP liked sweet more, but the reason for this relationship is not known. This difference could be due to tast...New winter hulless barley has high protein
...e, ulless barley is significantly higher in starch content and significantly lower in fiber than traditional hulled barley," he said. Virginia Tech released the first winter hulless barley cultivar, "Doyce," in 2003. The breeding program is developing both traditional soft red winter wheat cultivars and new...Discovery may lead to better Candidiasis drug
...ume and water content. Cells that lose their water content without being able to regulate its re-uptake die rapidly, Edgerton said. "Now that the target for histatin has been identified, we can design a better protein that will be even more effective in binding and holding the channel open, causing even bet...Defenseless plants arm themselves with metals
...Salt and his colleagues have shown that this metal content is what makes the plants resistant to pathogens. Salt proposes a scenario in which at some point in evolutionary history some plants acquired a mutation that disrupts the salicylic acid signaling pathway, leaving them unable to fight off pathogens. ...Scientists journey to southern Africa to unravel the secret world of elephant communication
... elephants and other species based on the spectral content of their footstep as they pass by a geophone array," says Jason Wood, who is leading the seismic censusing study. "The idea is to have geophone arrays that could be left in the ground for a month at a time, recording data without anybody having to be...Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma
...when two chromosomes break and trade their genetic content in what's technically called a "translocation," activating the oncogene EWS-FLI1 which triggers the tumor growth characteristic for this cancer. In their experiment, siRNA was delivered to this growth-promoting region of the tumor cell, effectively ......t.com. On the same site, customers can examine the content of Agilent-manufactured commercial microarrays and design their own custom microarrays. Agilent-manufactured microarrays are based on the industry-standard 1" x 3" slide format, making them readily and easily accessible to any researchers who want to...Virus-host interactions at sea effect global photosynthesis
...t.com. On the same site, customers can examine the content of Agilent-manufactured commercial microarrays and design their own custom microarrays. Agilent-manufactured microarrays are based on the industry-standard 1" x 3" slide format, making them readily and easily accessible to any researchers who want to...B-15A collides with Antarctic ice tongue
...t.com. On the same site, customers can examine the content of Agilent-manufactured commercial microarrays and design their own custom microarrays. Agilent-manufactured microarrays are based on the industry-standard 1" x 3" slide format, making them readily and easily accessible to any researchers who want to...Finding hidden invaders in a Hawaiian rain forest
...ometer (AVIRIS) to measure leaf nitrogen and water content from the aircraft, and corroborated the data on the ground. The fingerprints showed where the native dominant tree 'ohia' (Metrosideros polymorpha) has been taken over by the invading Canary Islands tree, Myrica faya, and more importantly identified ...Low oxygen likely made Great Dying worse, greatly delayed recovery
...ay. By the early Triassic period, sea-level oxygen content of less than 12 percent would have been the same a...iology Institute. Not only was atmospheric oxygen content dropping at the end of the Permian, the scientists said, but carbon dioxide levels were rising, lead...Scientists reveal the shape of a protein that helps retroviruses break into cells
...ay. By the early Triassic period, sea-level oxygen content of less than 12 percent would have been the same a...iology Institute. Not only was atmospheric oxygen content dropping at the end of the Permian, the scientists said, but carbon dioxide levels were rising, lead...wFleaBase: the Daphnia genome database
... community. Our challenge is to rapidly expand its content and to ultimately integrate genetic and functional genomic information with population-level responses to environmental challenges. ...Too much water may be as dangerous as too little during long-distance athletic events
... a condition marked by a loss in the body's sodium content that can result in physical symptoms such as lethargy, disorientation, seizures and even respiratory distress. In a perspectives article in the current issue of The New England Journal of Medicine, Dr. Benjamin Levine, professor of internal medicine...