Cardiologist's 'living chip' changes science of disease monitoring
...ent early on about a problem. The patient can then contact their physician. For a patient with heart failure, for example, the biosensor could detect a change in blood protein levels at an early stage, prompting the physician to alter medications to correct the problem. Currently, without blood work being ...Innovative movies show real-time immune-cell activity within tumors
...n actively migrating though tissues, making direct contact with tumor cells, and killing them. Insights from this new view of the body's on-board defenses against cancer may open the way for improved immunotherapies to treat the disease. With a series of movies made under different experimental condition...Newly discovered behavior in cancer cells signals dangerous metastasis
...peculate that this co-factor could be activated by contact with stroma --the supporting structural cells of a tumor -- because the stroma is where the majority of epithelial-type cancer cells were observed. Their heavy presence implies that the stroma may have induced the cancer cells to revert to epithelial...Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack
...ce exposure with someone who is contagious, direct contact with infected bodily fluids or a contaminated object, such as bedding or clothing, and exposure to an aerosol release. Routine smallpox vaccination ended in 1972, which leaves at least 43 percent of the U.S. population unvaccinated, Longini said. R...Adolescent but not adult hamsters are more aggressive on low dose of fluoxetine
...nters to document behaviors such as attacks, pins, contact time, contact bouts and target of attack. The adult hamsters treated with either dose of fluoxetine became ge...Worms produce surprise insight into human fever
... the two target pathways as they came into direct contact with a small zoo of pathogenic microbes. The big surprise was the discovery that the HSF-1 pathway was required for C. elegans immunity against Pseudomonas aeruginosa, Salmonella enterica, Yersinia pestis, and Enterococcus faecalis. It indica...Leading reason for corneal transplants comes into focus
...ing it impossible to see well even with glasses or contact lenses. It's believed that various forms of FCD are due to multiple gene mutations. In a report in the September issue of Investigative Ophthalmology, a team led by Hopkins ophthalmologist John Gottsch, M.D., says they were able to map a common ...Pattern of human Ebola outbreaks linked to wildlife and climate
... that public education is needed to decrease human contact with potentially infected wildlife by discouraging people from scavenging dead animals and by promoting safe hunting and trapping practices, especially because the results show that outbreaks in wildlife populations have been much more frequent than ...An artificial cornea is in sight, thanks to biomimetic hydrogels
...lications of the hydrogel include more comfortable contact lenses. Onlays of hydrogel lenses on the surface of the cornea could serve as extended-wear contact lenses. Inlays are also possible. The cornea contains layers--a top layer of protective epithelial...Artificial cornea offers better results for infants, some blind patients
...dies of infants and adults, is about the size of a contact lens and is sewn into the patient's eyeball with a...esigns. The latest procedure also includes a large contact lens placed over the cornea to help protect it from inflammation and scarring. After the procedure p...Robotic whiskers can sense three-dimensional environment
...an be deflected backwards, upwards or downwards by contact with the object. The mechanical bending of the whisker activates many thousands of sensory receptors located in the follicle at the whisker base. The receptors, in turn, send neural signals to the brain, where a three-dimensional image is presumably ...The power of one: A simpler, cheaper method for cell fusion
...s chamber within the chip, where they pair off. In contact with one another but not yet fused, the cells flow towards the only exit, which is a miniscule gap that channels electricity from one pole to the other. Passing through this narrow section, cells are subjected to a strong electrical field that causes...Discovery of the first resistance gene to rice yellow mottle virus
...urs by way of insect vectors or by straightforward contact between plants. Prevention measures, like direct sowing or the burying of straw, have been implemented in order to limit the spread of the disease, but the real potential for reducing the impact of RYMV is to be found in the use of resistant varietie...Discovery in the evolution of the immune system absorbing cells
...es belong to this group and they are constantly in contact with a vast multitude of microorganisms in the water. According to Dr Sunyer, "From a practical perspective, this discovery will be used in the near future to produce a new design of vaccines for fish in order to stimulate phagocytosis in antibodies ...New approach to BSE successful in lab
...is that they have a different shape. When there is contact with their ‘diseased twins?they change their shape, also becoming ‘diseased.?The result is an irresistible chain reaction. The malformed prion proteins can be deposited in the brain, thereby destroying brain tissue. Prion diseases are always fatal, o...Stem cells engage in dialogue with the cells that regulate their futures
...lls. Cap cells adhere to stem cells and this close contact may allow cap cells to play critical roles in comm...a kind of signaling that usually depends on direct contact between cells, called the Notch pathway. The Notch protein is like a trigger poking out of a cell th...Nobel Laureate finds 'elegant' explanation for DNA transcribing enzyme's high fidelity
...trigger loop, which makes both direct and indirect contact with all features of the nucleotide in the polymerase active center,?the researchers concluded. ...Interaction between lymph and liver cells may affect immune response
...ithin the fenestrations and were observed to be in contact with minute projections on liver cells (hepatocyte microvilli). There were no observable gaps between LSECs and hepatocyte microvilli did not seem to interact with circulating lymphocytes. Further investigation showed that naïve T cells displayed the...White blood cells of cancer-resistant mice overwhelm natural defenses of cancer cells
... Macrophages, for instance, have to be in physical contact with the cancer cell before unleashing its combination of killer molecules. White blood cells from the cancer-resistant mice apparently have the same ability to attack a range of tumors when transplanted to ordinary mice. Cui and Willingham also...... the only available test that requires no physical contact with participants. Thermography is currently the only method that can be used to diagnose sexual health problems in both women and men. In fact, women and men demonstrated similar patterns of temperature change during sexual arousal with no significa...