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Tag: "conserved" at biology news

Where 'jumping genes' fear to tread

...posons. The locations of these regions are highly conserved among mammalian species and are enriched in genes ...tor. It appears that many TFRs are evolutionarily conserved features that existed prior to ?and have been largely maintained since ?the divergence of eutherian ...

Salmonella bacteria use RNA to assess and adjust magnesium levels

...u would expect to find that a DNA sequence that is conserved among different species is encoding part of a protein," Groisman says. "But here we're talking about a part of a message that does not encode a protein. So why would it be conserved? There must be some important role that the sequence is fulfilling t...

Study finds 60 new genes controlled by DNA snippet

...f genetic material, gene or regulatory segment, is conserved by evolution from mice to humans it suggests that the segment has a valuable function. Miano's screen required that CArG boxes shared by humans and mice be included in his expanded version of the CarGome. CArG boxes identified by the computer screen ...

New method for identifying microbes

...at codes for a piece of the ribosome -- the highly conserved "single point" reference gene. By sequencing these tags and comparing the sequenced code with databases of known bacterial genomes, the Brookhaven team determined that this specific 16-letter region contains enough unique genetic information to succe...

Common molecular 'signature' identified in solid tumors

... hundreds of miRNAs and found that they are highly conserved over time ?meaning that they show up in generation after generation in everything from plants to mice to humans ?confirming their important roles in growth and survival. Carlo Croce, professor and chair of molecular virology, immunology and medical...

Genomatix technology facilitates de novo identification of new renal disease associated genes

...f the glomerular slit diaphragm. An evolutionarily conserved promoter model was generated. Genome-wide scans using this promoter model effectively predicted a previously unrecognized slit diaphragm molecule which was then experimentally verified. This publication shows a straightforward approach how comparat...

Discovery may speed forest biotechnology

...ring. They discovered that the same genes had been conserved through millions of years of separate evolution and also performed similar functions in aspen trees. To their surprise, however, the researchers found that the CO/FT combination also controlled the cessation of vegetative tree growth in the fall ?so...

Value of services performed by insects tops $57 billion in US

...f insects so that the services they provide can be conserved or even enhanced. ...

New fruit fly protein illuminates circadian response to light

...d for the circadian light response in flies may be conserved in humans. Over time, we will have a better understanding of how the human clock responds to light and may be able to design drugs to treat jetlag," concludes Sehgal. ...

Major obesity gene is 'lost in the shuffle'

.... They discovered that the ASIP gene was highly conserved among most of these primates, but, surprisingly, a 100-kilobase segment of DNA harboring the ASIP gene was missing in gibbons. "We found that this deletion occurred between two pieces of DNA that are quite abundant in primate genomes, called Alu e...

New human retrovirus originated in mice

...e they invariably contain sequences that have been conserved in their evolution from related viruses. The initial screen of the RNASEL-mutant prostate cancers revealed the presence of a genetic sequence that closely resembled that of a mouse virus called murine leukemia virus (MuLV). Murine leukemia virus is ...

Scientists elucidate the kinome of key model organism

...ostelium provides a simple model in which to study conserved cellular processes, and illuminates a period in th...authors find 46 types of kinases that appear to be conserved in all organisms, and are likely to be involved in fundamental cellular processes. "We believe this ...

Scientists discover a genetic code for organizing DNA within the nucleus

...f the nucleosome are among the most evolutionarily conserved in nature, the scientists believe the genetic code they identified should also be conserved in many organisms, including humans. Several diseases, such as cancer, are typically accompanied or ...

Molecular DNA switch found to be the same for all life

...arently worked so well early on that evolution has conserved it across the eons in all forms of life on Earth. ...and the degree to which these mechanisms have been conserved by evolution have been ill defined and hotly debated," said biophysicist Eva Nogales, a collaborator...

Basic work on E. coli identifies two new keys to regulation of bacterial gene expression

...hin DNA promoters that makes contact with a highly conserved but previously underappreciated segment of the sigma subunit of RNA polymerase. While the contact with sigma is very strong at promoters for most genes, it is particularly weak at promoters that make ribosomal RNA, which means that other factors like...

No-mow grass may be coming to your yard soon

...emarkably, steroid biosynthetic enzymes are highly conserved from plants to metazoans (animals), suggesting that the use of steroids as hormones preceded the plant-animal split over a billion years ago," Chory explained. In animals, the route steroid hormones use to exert their influence in the nucleus of a ...

St. Jude test of bird flu vaccine proves successful

...ther version of the vaccine contained only the two conserved viral proteins. In the St. Jude study, the full, three-component vaccine (H5, NP and M2) provided complete protection in mice against lethal challenges with a highly virulent (Vietnam/1203/2004) H5N1 avian influenza virus. Moreover, other studies s...

Scientists' cell discovery unearths evolutionary clues

...the family tree by amplifying and comparing highly conserved genes from all known species of social amoeba. The existing family tree of the social amoeba was based on how the multicellular structures of each species look on the outside. However, this tree was completely uprooted by the molecular data gathe...

How nature tinkers with the cellular clock

...though most components of the cell cycle have been conserved over one billion years, the temporal regulation of...a cell that its machinery has been almost entirely conserved through evolution. Crucial components are made only at specific times to ensure that each machine is...

Jefferson researchers uncover new way nature turns genes on and off

...igher eukaryotes, and it is very likely that it is conserved in mammals." Understanding the details of the TrxG system could someday have implications for ALL, a dangerous type of childhood leukemia. The disease stems from gene rearrangements in utero. MLL, the gene that is affected in humans, corresponds...

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