conserved 2 3

Tag: "conserved" at biology news

Zebrafish may hold key to improved cancer research

...pelling, said Spitsbergen. The B-myb gene has been conserved through hundreds of millions of years of divergent evolution in species ranging from worms to fruit flies, fish and humans. When it functions normally, B-myb appropriately regulates cell proliferation. When it becomes mutated, either through genetic...

The earliest animals had human-like genes

...ight well give us an even better look at important conserved processes. Another thing that this has shown us is that evolution is not always about gain; the loss of complexity can equally be an important player in evolution." ...

CO2 sensing proves critical for fungal pathogens to adapt to life in air and human hosts

... CO2 sensing and metabolism utilize evolutionarily conserved enzymes to control the growth and sexual reproduction of pathogenic microbes. The two studies are reported by Joseph Heitman and colleagues at Duke University Medical Center and by Fritz Mühlschlegel of the University of Kent, Jochen Buck at Cornel...

MicroRNA gene that regulates lifespan found by Yale scientists

...n-driven metabolism and aging. "This microRNA is conserved in humans leading to the enticing idea of being able to beneficially affect the results of aging including diseases of aging," said Slack. Work is under way to identify other microRNAs regulators and genes they target, to determine where they functio...

Membrane research opens window to benefits for plants, humans

...because sequencing has shown the gating loop to be conserved in them. "Plant cells close their water channels in response to drought stress in order to preserve their water content," said Tajkhorshid, who also is assistant director of research of the Theoretical and Computational Biophysics Group at the U. of...

Evolutionary conservation of a mechanism of longevity from worms to mammals

...ivity that was initially observed in C. elegans is conserved in mice, supporting the idea that some molecular mechanisms of aging are shared throughout the animal kingdom." ...

A resetting signal keeps circadian rhythm on track in Drosophila fruit flies

...cadian clocks and even neural mechanisms are quite conserved with mammals." "We were curious about how these brain cells stay synchronized, so we controlled the way time was ticking in individual clocks: we made the morning cells run faster and the evening cells relatively slower, and the other way around," e...

Researchers discover new form of cancer gene regulation

...ly, the study demonstrated that this regulation is conserved from human to the worm, Caenorhabditis elegans (often used in laboratory research), indicating that the formation of these RNA protein complexes is a very ancient form of regulation of protein function. Olga Lakiza, postdoctoral fellow in pediatric...

Researchers develop new method to help find deadly malaria parasite's Achilles heel

...ed that yeast, worm, and fly have hundreds of both conserved proteins and protein interactions, we didn't initially believe our own analysis, which showed that there are only three Plasmodium protein interactions in common with yeast and none in common with the other species studied."The World Health Organizat...

Yale scientists decipher 'wiring pattern' of cell signaling networks

...gnal disease." Biological networks are typically conserved between species, meaning that often the same type of protein carries out the same type of function, whether it is in a yeast cell or a human cell. According to Snyder, these findings in yeast are of immediate use for understanding both human developm...

Marsupial genome reveals insights into mammalian evolution

...t have important functions and therefore have been conserved for long periods of time. The monotremes split off from other mammals 210 million years ago. The remaining marsupials split from the main (placental) group about 180 years ago." Significantly, the authors also found data supporting the idea that th...

Common molecular 'signature' identified in solid tumors

... hundreds of miRNAs and found that they are highly conserved over time ?meaning that they show up in generation after generation in everything from plants to mice to humans ?confirming their important roles in growth and survival. Carlo Croce, professor and chair of molecular virology, immunology and medical...

Wisconsin scientists discover a master key to microbes' pathogenic lifestyles

...cel Wuthrich identified a molecular sensor that is conserved in these six related dimorphic fungi found worldwide. The sensor, says Klein, is like an antenna situated in the membrane of the fungi's spores. It senses temperature, and when a spore finds itself at a comfortable 37 degrees Celsius, the body temper...

The evolution of food plants: Genetic control of grass flower architecture

...rass family, because the ra2 expression pattern is conserved in other grasses including rice, barley, and sorghum". Perspective : Branching Out: The ramosa Pathway and the Evolution of Grass Inflorescence Morphology In an accompanying Current Perspective Essay, Paula McSteen of The Pennsylvania State Univer...

Novel molecular 'signature' marks DNA of embryonic stem cells

... of chromatin that control the most evolutionarily conserved portions of DNA, particularly the key regulatory genes for embryonic development. "These signatures appear frequently in ES cells, but largely disappear once the cells choose a direction developmentally," said Bernstein. "This suggests they play a s...

NHGRI announces new sequencing targets

...mparisons among the 24 genome sequences will allow conserved sequences as small as six base pairs to be identified reliably. Six base pairs is roughly the size of a transcription factor binding site: a small DNA sequence occurring near a gene that is involved in switching the gene on or off. Sequencing effort...

Polymer aids in blood clotting, pointing way to new treatment

...but scientists thought it to be a molecular fossil conserved from prebiotic time. "This is something that has mainly been studied in bacteria," Docampo said. "There is almost no data on polyphosphates in vertebrates, including humans. No role was seen for them, so there was little interest in studying them." ...

New mechanism for essential genome-wide gene silencing identified

...al nature, critical genetic systems are frequently conserved with few changes in life forms that diverged during evolution millions of years ago. "In our experiments, we saw SUMO binding to histones across the genome, suggesting that if this mechanism went wrong, it could have a dramatic effect," says Berger....

Insects and mammals share common fat-building pathway, study suggests

...ies and mice. The findings are the first to show a conserved effect of genes on fat storage from insects to mam... data support the notion that Hh signaling plays a conserved role, from invertebrates to vertebrates, in inhibiting fat formation and highlighting the potential ...

For the first time: Longevity modulated without disrupting life-sustaining function

... cascade including the newly identified protein is conserved across many species, including humans, these findings raise the prospect that one day it might be possible to medically tweak this pathway to slow aging and improve the quality of life without harmful consequences to the body. In humans and other m...

1 2 3 4 5 6