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Tag: "confirmed" at biology news

New influenza vaccine takes weeks to mass produce

...e 100% effective in the prevention of cell culture confirmed influenza. Wang and his colleagues report the successful production of rHA from 4 strains of influenza that scientists believe to be likely the cause of the next pandemic (H5, H7, H9, and H2) at a level where manufacturing costs are expected to be ...

Darkness unveils vital metabolic fuel switch between sugar and fat

...ign of torpor. Core body temperature measurements confirmed their lethargic state. Mice kept in constant dark also ate less, lost weight, and showed evidence of increased fat consumption, all hallmarks of hibernation in larger mammals. The authors note that 5'-AMP has previously been shown to regulate enzy...

Cholesterol gets 'thumbs up' for role in digit development

...malous digit duplications. Chiang and colleagues confirmed this microscopically, showing that the protein spread out more evenly across the limb bud (a weaker gradient) in mice lacking cholesterol-modified Sonic hedgehog compared to normal animals. "We found that, without cholesterol, Sonic hedgehog moves ...

Warbling whales speak a language all their own

...nimal kingdom. Researchers have now mathematically confirmed that whales have their own syntax that uses sound units to build phrases that can be combined to form songs that last for hours. Until now, only humans have demonstrated the ability to use such a hierarchical structure of communication. The research...

Scientists design potent anthrax toxin inhibitor

... of anthrax inhibitors designed in this fashion is confirmed by additional testing, they could one day be important adjuncts to standard antibiotic therapy for the treatment of inhalation anthrax," says NIAID Director Anthony S. Fauci, M.D. The spore-forming bacterium Bacillus anthracis produces a toxin that ...

Successful cell engineering may lead to mad cow prevention, say researchers

...ly dies. More than 180,000 cases of BSE have been confirmed worldwide, including recent cases in the United States. The disease can be passed to humans, and more than 100 such cases have been confirmed, most of those in England. "The next step is to try and avoid the cloning process - to skip that step if po...

MIT: Oceans are a major gene swap-meet for plankton

...t laboratory experiments with the cultured strains confirmed this idea. Further analysis showed that most of the genetic differences between the two super-abundant strains are concentrated in a few "genomic islands," small zones where different kinds of genes get swapped in and swapped out, known among molecu...

Ernst Mayr's theory illustrated in genetic epidemiology studies

...er the place, so that modern molecular biology has confirmed Mayr's idea of genetic architecture," Templeton said. "Given that you have this interaction it's inevitable that a random process like drift will interact with natural selection strongly to spark new directions of evolutionary change." The other t...

Antioxidant selenium offers no heart-disease protection

... of significant association with CVD endpoints was confirmed even in the 246 participants who had CVD at baseline. (This data does not appear in the published manuscript.) "These results must be interpreted cautiously," said Stranges, "because they result from exploratory analyses, although from the largest r...

Flesh-eating bacteria escape body's safety net

...ritical role of the DNA-degrading Strep enzyme was confirmed by cloning the corresponding gene into a normally non-pathogenic bacterial strain. Addition of the single gene allowed these bacteria to degrade DNA, escape neutrophil killing, and produce a spreading ulcer in the mouse infection model. Special flu...

Climate change: The rice genome to the rescue

...ave to double over the next 50 years. Research has confirmed that global warming will make rice crops less productive with increasing temperatures decreasing yields. "Clearly, climate change is going to have a major impact on our ability to grow rice," Robert S. Zeigler, IRRI director general, said. "We can't...

Oceans are 70 percent shark free

...ast Atlantic. The scientists say that the deepest confirmed report of a shark is at 3,700m. They believe it is very unlikely that major new populations will be discovered in abyssal regions. Professor Priede added: "As far as we can see there is no hidden reserve of sharks in the deep sea. All we see, is al...

Enzyme inhibitors block replication of SARS virus

...hen inactivated the SARS enzyme. The findings were confirmed using mass spectrometry analysis of the enzyme intermediary. "These benzotriazole esters are relatively stable and act as suicide inhibitors," Wong said. "They block the enzyme, are transformed through a co-valent bond, and are unable to get out."...

Researchers use 'trickery' to create immune response against melanoma

...fter incubation with the prostate cancer cells and confirmed that the particles were rapidly internalised into the targeted cells ?an important fact since the payload of nanoparticles may be released inside the cancer cells in a regulated manner over an extended period of time. The study principle investigat...

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

...fter incubation with the prostate cancer cells and confirmed that the particles were rapidly internalised into the targeted cells ?an important fact since the payload of nanoparticles may be released inside the cancer cells in a regulated manner over an extended period of time. The study principle investigat...

Argonne researchers confirm lead in Beethoven's illness

...chronic debilitating illness. The bone fragments, confirmed by DNA testing to have come from Beethoven's body, were scanned by X-rays from the Advanced Photon Source at Argonne, which provides the most brilliant X-rays in the Western Hemisphere. A control bone fragment sample from the same historic period was...

'Computer-chemistry' yields new insight into a puzzle of cell division

... first author was Rudolph's graduate student Sohn, confirmed the calculations with extensive biochemical evaluations of the two hot spot residues the study identified, one residue on the phosphatase and the other on the kinase. Both hot spots are located some distance from the molecules' active sites, Rudolph ...

New study of the world's smallest elephant

...ee years. The Bornean elephant has recently been confirmed as a separate sub-species, dramatically increasing its importance for biodiversity. Bornean elephants are the world's most endangered member of the elephant family with an estimated 1,100 - 1,500 surviving in the wild. The Cardiff School of Biosc...

Plants, too, have ways to manage freeloaders

...stinguish them." In a subsequent experiment, they confirmed that the larger the root nodule, the more nitrogen-fixing bacteria it contained. Only rarely did they find more than one strain of microbe in a nodule, though a single plant might nodulate more than one strain in separate nodules. "These results sup...

Eisai announces Phase II data on E7389, a potential new therapy for the treatment of breast cancer

...e 65 evaluable patients, 10 partial responses were confirmed at the 4th cycle assessment. Twenty-one patients had stable disease (SD). In treatment-refractory patients with advanced breast cancer this preliminary response rate (15%) appears promising. Based on the preliminary results of this study, the predo...

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