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Tag: "confirmed" at biology news

Research links 'ecstasy' to survival of key movement-related cells in brain

...re to MDMA in cultured embryonic cells--where they confirmed that this drug was in fact increasing dopamine cell survival. The findings, Lipton says, aren't consistent with what is known about adult brains, where MDMA has been shown to cause depletion of neurotransmitters--like dopamine--and has been linked...

Three-dimensional, miniature endoscope opens new diagnostic possibilities

... areas of tumor nodules, the presence of which was confirmed by histologic analysis of the tissue. "The most important feature of this new endoscope is the ability to obtain three-dimensional images, something we don't believe is offered by any commercially available miniature endoscope system," says Dvir Y...

Bacteria that use radiated water as food

... molecules to useable energy. The discovery is a confirmed expansion of Earth's biosphere, the three-dimensional shell that encompasses all planetary life. The research has less Earthly implications, however. It will likely fuel optimism that life exists in other deep subsurface environments, such as in gr...

A wolf in sheep's clothing: Plague bacteria reveal one of their virulence tricks

...ed to the original wild-type Yersinia. His results confirmed the hypothesis from the structural study: While the wild-type YpkA wreaked havoc on their host cells' cytoskeletons, the mutant left the actin-based skeleton intact. Then, the researchers took it one step further. Stebbins and Prehna worked with col...

Intrinsic eye protein halts angiogenesis

...cornea. They studied a wide variety of mammals and confirmed the effect in each species including humans. "The millenia-old mystery of corneal avascularity has been the subject of serious scientific inquiry for 50 years. The significance of this publication is that we have now identified a single protein res...

Wheat gene may boost foods' nutrient content

...without differences in grain size. This experiment confirmed that this single gene was responsible for all these changes." Dubcovsky said the research team was surprised to find that all cultivated pasta and bread wheat varieties analyzed so far have a nonfunctional copy of GPC-B1, suggesting that this gene ...

New data from NIH lab confirms protocol to reverse type 1 diabetes in mice

...s published in the March 24, 2006 issue of Science confirmed that the MGH-developed protocol can reverse the un...et recovery, first described in the 2003 study, is confirmed in the current work. NIH researchers used cell lineage tracking in the form of Y-chromosomal fluore...

Chemotherapy temporarily affects the structures of the human brain

... blood-brain barrier, recent clinical studies have confirmed declines in cognitive functions in patients receiving chemotherapy. Animal studies have shown physical changes in the brain and in neurons caused by chemotherapy drugs. In human studies, however, the little data that is available is only available th...

Restoring tamoxifen sensitivity in resistant breast cancer cells

...ed disulfide benzamide, or DIBA. The investigators confirmed their study hypothesis about DIBA's effect on tamoxifen resistance by using the compound in mice that were engineered to have tamoxifen-resistant tumors and saw that tumor growth was reduced by nearly 50 percent when DIBA was administered. "Exposur...

A simple feedback resistor switch keeps latent HIV from awakening

...r-dependent switches, and cell-sorting experiments confirmed this prediction. This simple switch, in which the deactivating reaction overpowers the activating rea ction under most circumstances, acts as a "feedback resistor," and its general features, the authors suggest, are likely to be found in other sys...

Microcapsules like it hot and salty

... capsules and vice versa. This prediction was also confirmed in experiments. This continuous switching between the two states of quite different capsule sizes expands the range of possible uses for the Potsdam microcapsules enormously. As well as being used as medicine transporters, conceivable applicatio...

A new jump start for aging blood vessels

...four notable findings in their study. First, they confirmed that in advanced aging, increased TNFa levels were associated with significant impairment of vessel relaxation, which is required for proper regulation of blood pressure. Second, blocking TNFa via chronic etanercept treatment decreased cell deat...

Pure carbon nanotubes pass first in vivo test

.... "I still remember how excited we were when we confirmed that the tubes were fluorescing," said Paul Cherukuri, a doctoral degree candidate in Chemistry. The researchers used this fluorescence to track the nanotubes in the blood and image them in tissues under the microscope. Cherukuri said Smalley init...

Bacterial protein shows promise in treating intestinal parasites

... and at what concentrations. "These experiments confirmed that the mechanism of action of Cry5B in Ancylostoma hookworms appears to be identical to that for other nematodes, including C. elegans," said Cappello. "This suggests that crystal proteins will likely have activity against a broad range of nematod...

Scientists identify 36 genes, 100 neuropeptides in honey bee brains

...uences of more than 200 possible neuropeptides and confirmed the sequences of 100 neuropeptides from the brain of the honey bee. "This study lays the groundwork for future molecular studies of honey bee neuropeptides with the identification of 36 genes, 33 of which were previously unreported," the researcher...

Jumping gene could provide non-viral alternative for gene therapy

... spot in the genome, that would be beneficial." He confirmed that targeting integration is possible in a paper he co-authored in 2005 also in The FASEB Journal. "We can do it in insects," says Dr. Moisyadi. "I think it's a short step to take it to a targeting mechanism we can use in humans." Another clear b...

Beauty and the brain

...) and, without having to rely on reported ratings, confirmed a genuine positive response to those images that were closest to prototype. "It seems you don't need to postulate an unconscious calculator of mate value or any other 'programmed-brain' argument to explain why prototypical images are more attracti...

Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax

...n inhalational exposure. Animal experiments have confirmed the prolonged persistence of spores and incubation period after aerosol exposure. In one study, rhesus macaques were protected during a 30-day course of antibiotics after aerosol exposure. However, some animals developed fatal infection after the an...

Tests for 'face-blindness' reveal disorder may not be so rare

...r remains poorly understood, although research has confirmed that the brain processes faces differently than other kinds of objects. The condition can be embarrassing and lead to social isolation: Severe prosopagnosics may mistake complete strangers for acquaintances even as they fail to recognize family mem...

Genetic 'roadmap' charts links between drugs and human disease

...small fraction of available drugs, we have already confirmed several biological connections between drugs and h...p to help uncover its precise molecular action. As confirmed through additional work, gedunin disrupts a key quality control mechanism in the cell. Another key...

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