Scientists unlock mystery of embryonic stem cell signaling pathway
...tive Medicine at the Keck School of Medicine, have confirmed that IQ-1 plays a similar role in that system as well. “If we can create a totally chemically defined system for growing human embryonic stem cells without any risk of contamination, it would make life much easier for scientists than it is at the ...RNAi shows promise in gene therapy, Stanford researcher says
...f the wrong gene or genes. In work last year, Kay confirmed those findings but also showed a possible way around those toxic effects by selecting particular RNA sequences. "One benefit of RNAi gene therapy is that it uses the body's own machinery, making it an effective approach," Kay said at the time. ...New research may overturn conventional wisdom on drug-resistant tuberculosis
...due to new infections, not acquired resistance. If confirmed in future studies the research, in the March 15 issue of The Journal of Infectious Diseases, may drive a major shift in strategy for controlling TB. A major difficulty in treating patients with pulmonary TB is that the organism can become progressiv...The connector rotation hypothesis? Phage do not pack their DNA by rotation
... mathematical analysis of the fluorescence pattern confirmed that the changes in the fluorescence emitted by the molecules as packaging took place did not correspond to any sort of continuous rotational motion. The researchers concluded with more than 99% certainty that the packaging mechanism does not involve...Anti-herpes treatment reduces HIV levels in women infected with both viruses
...sion of the virus. The findings will need to be confirmed by further research, and there is already a large ongoing trial that is measuring direct transmission of HIV between discordant couples in several sites worldwide. Dr Philippe Mayaud, one of Dr Nagot's colleagues at the LSHTM concludes: 'Our resul...Killing the messenger RNA -- But which one?
...p to about two times what they should be. "This confirmed that our original computer prediction of differential targeting by unedited and edited microRNAs of different sets of genes is likely to be correct," Nishikura says. "And in at least the case of the one gene we investigated, this differential has phy...Light-based probe 'sees' early cancers in first tests on human tissue
...the preliminary success of the "optical biopsy" is confirmed through clinical trials, such a device could ultimately provide a particular advantage for early diagnosis, treatment and prevention of many types of cancer, according to the researchers. The vast majority of cancers start in the body's epithelial ce...Genes and genius: Researchers confirm association between gene and intelligence
...ain influences one kind of intelligence. They have confirmed a link between the gene, CHRM2, and performance IQ, which involves a person's ability to organize things logically. "This is not a gene FOR intelligence," says Danielle M. Dick, Ph.D., assistant professor of psychiatry and lead author on the stud...Scientists identify a candidate gene for osteoporosis
...search . "If our finding using the mouse model is confirmed in humans, then we may be able to develop therapies that are based on inhibiting the function of the DARC gene," explains Dr. Subburaman Mohan, Ph.D., a Senior Scientist at the Loma Linda VA Medical Center and a Professor of Medicine and Biochemist...Reversing cancer cells to normal cells
... Findings from the zebrafish study were further confirmed in the human embryonic stem cell model and the chick embryo model - where inhibiting Nodal signaling led to the reversal of the melanoma cells to a more normal cell type. This is a promising area of research, says Dr. Hendrix. The discovery of a ...Widely used hepatitis B drug spurs HIV drug resistance
...ostered development of this mutation in HIV, later confirmed by clinical testing. When researchers tested the blood of one of the co-infected patients for the M184V mutation, they found none in samples taken at the start of entecavir thereapy. But they did find it in 61 percent of viral samples tested afte...New fMRI technology making brain tumor surgery safer
...us far, Dr. McPherson said, the double checks have confirmed the technology’s accuracy while suggesting that the technology may make brain stimulation unnecessary for many surgeries in the future. The new BrainLAB equipment also enables physicians to integrate diffusion tensor imaging (DTI), which provide...Researchers show that veins stiffen as we age
...he Christiana Care Health System in Newark has now confirmed that even our veins stiffen as we age. "When you are young, your veins are nice and elastic--like rubber bands," William Farquhar, a cardiovascular physiologist in UD's College of Health Sciences, said. "But as you grow older, we've found that your...Microbes compete with animals for food by making it stink
...ant it." Counting the species found in the traps confirmed the level of attraction to the various forms of the bait, but it didn't necessarily test feeding, Hay noted. "It could be that the rotten food is just as good, but a lot of the good smells have leached out in the water, so maybe it's just food that's...Gene key to taste bud development identified
...eas in the esophagus. Further studies, Hogan said, confirmed that SOX2 was present in high amounts during the development of taste buds. In another set of experiments, Hogan's team used another variant of the mouse strain made by Pevny in which the SOX2 gene was altered to produce only low levels of SOX2. In...Growth factor stimulates rapid extension of key motor neurons in brain
...nal cord prevented the growth of CSMN axons, which confirmed the applicability of the in vitro experiments to living mammals. "The role of IGF-1 as a potent and specific enhancer of CSMN axon growth is highly relevant to our understanding of this critical population of neurons. These findings are a first ...Radiation after surgery doubles survival time for some lung cancer patients
... data observed in this study, however, needs to be confirmed in a prospective randomized trial of radiation, in addition to chemotherapy." ...Underweight women at greater risk of miscarriage
...ctors in their most recent pregnancy. The findings confirmed the findings of previous studies into possible risk factors, for example in relation to increased maternal age and alcohol consumption, but they also revealed a number of interesting new associations. They found that underweight women were 72% mor...New bird discovered on unexplored Columbian mountain
...nge. Genetic, morphological and vocal studies have confirmed its identity as a new taxon. "Before we began this study, no one knew what species lived in the Yariguíes Mountains and whether they needed protecting," said Thomas Donegan. "Now, we are beginning to describe new taxa and a national park was estab...Researchers link ocean organisms with increased cloud cover and potential climate change
...easured in highly polluted areas of the globe. If confirmed by field studies, this connection between clouds a...global climate models, however, it will have to be confirmed by field experiments. Atmospheric scientists believe that by blocking sunlight, increased cloudin...