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Tag: "confirm" at biology news

Study of gene transfer for erectile dysfunction shows promise

...control" group treated with a placebo is needed to confirm the safety and effectiveness of the treatment. Other researchers on the project were Melman, Natan Bar-Chama, M.D., with Mount Sinai School of Medicine, Andrew McCullough, M.D., with New York University School of Medicine, and Kelvin Davies, Ph.D...

Combination therapy shows promising results in patients with advanced lung cancer

...inor. The next step is a larger Phase II study to confirm the efficacy of the combination therapy and further probe the mechanisms of Tarceva resistance, Reckamp said. That study is expected to begin at UCLA in the fall. Reckamp's study was the first to determine the safest and most effective dose of Celeb...

Unique soybean lines hold promise for producing allergy-free soybeans

...g stronger antibodies and protein gels was done to confirm the absence of P34 in the two domestic lines, Joseph said. After the two lines were isolated, seeds were sent to the Danforth Center for additional molecular analysis to determine why P34 was absent. Six identical genetic mutations were found in eac...

Researchers find protein that silences genes

... they switch from off to on, the group was able to confirm that the deacetylation specificities they observed for HDA6 in the test tube fit with the changes in acetylation that occur on ribosomal RNA genes in living cells. They also found that the mechanism behind the silencing involves both modifications ...

Gene linked to rare disease activates fat breakdown

...self acted as a lipase. However, studies failed to confirm its lipid-busting activity and its role remained mysterious. Triglycerides consist of three fatty acids, each of which is removed in a "step-wise affair" from its glycerol backbone, Zechner explained. One of the lipases responsible, hormone-sensitiv...

Selectively blocking inflammatory signals may protect mice from MS

...ly showed how it harmed oligodendrocytes. Here we confirm its direct harmful effects on those cells and demonstrate one way of protecting them." The researchers produced a series of transgenic mice. In one set they introduced genes that produced interferon-gamma within the central nervous system. In anot...

Fertility hope as study shows eggs survive in older ovaries

...nity, the scientists could not produce evidence to confirm their idea. However, Professor Findlay and Dr Kerr's research gives support to the theory. Their findings have been published in the July issue of Reproduction. In the mammalian ovary, reproductive cells called oocytes (eggs) develop within ovarian...

Bone marrow may restore cells lost in vision diseases

...body. In this case, the cells were transplanted to confirm that bone marrow does regenerate the injured RPE. It was easier to track male, pigment-producing cells in female, albino recipients, Harris said. Chemical and microscopic analysis showed the cells that traveled to the injury site and transformed int...

Massive duplication of genes may solve Darwin's 'abominable mystery' about flowering plants

...family. The new results from the Penn State paper confirm a previously-reported paleopolyploidy event in eudicots (a group that includes beans, tomatoes, sunflowers, roses, and apples) associated with their rapid divergence, and demonstrates the first evidence of a paleopolyploidy event associated with the ...

Parallel evolution: Proteins do it, too

...ian and African---split into separate lineages. To confirm that the duplication occurred after the split, he analyzed DNA samples from an African colobine known as the guereza or colobus monkey. "We sequenced the gene, and to our surprise we found not one, not two, but three RNASE1 genes," Zhang said. "Fur...

Researchers discover which organs in Antarctic fish produce antifreeze

...the fish serum. "In this comprehensive study, we confirm that the exocrine pancreas is the major AFGP synthesis site in Antarctic notothenioid fishes from hatching through adulthood, while the liver is AFGP-expression null in all life stages," the researchers conclude. "Because the notothenioids are confin...

Novel therapy combinations gain ground in treating hepatitis

...nced viral breakthrough at any time. "These data confirm the rapid and dramatic antiviral effects of VX-950. All subjects achieving undetectable HCV RNA within 28 days of treatment is an unprecedented result with an investigational agent," said Eric Lawitz, M.D., of Alamo Medical Research, Texas, and lead...

Friendly bacteria in chewing gum that bites back

...due to hit the supermarkets in 2007, but would not confirm whether it is the chewing gum. Marcinowski says that the chewing gum 'has been tested on large numbers of people and demonstrated the ability to significantly reduce bacterial levels.' A new range of toothpastes and mouthwashes using L. anti-caries a...

Memory loss affects more of the brain than previously thought

...are in the process of completing a larger study to confirm these results and to examine their value as a diagnostic or predictive test. There have also been a number of previous fMRI studies in people with MCI, and researchers are working to put these findings together to develop a synergistic combination o...

Johns Hopkins lab scientists tame overactive CF protein

...oys to seek out the mutant CFTR. "We were able to confirm that to get rid of the defective CFTR protein, cells deploy VCP/p97 protein, which latches onto the damaged CFTR and sends it to the proteasome for destruction," Zeitlin says. "Using RNA interference, which basically works by silencing the expression...

Biodiversity key to sustainable biofuel according to University of Minn. researcher's findings

... in an experiment that controlled biodiversity ?to confirm the theory. The time period of the study allowed researchers to evaluate the average net effects of diversity on resistance to and recovery from drought, pests, disease and other disturbances. Tilman and his collaborators began the work in the early ...

COX-2 inhibitors significantly reduce risk of cancer

...to go out and start taking them until more studies confirm that they are safe and effective," says Harris. Celebrex is still widely used for pain relief, but Vioxx was pulled off the market in 2004 following reports of heightened risk of heart attacks. "It's clear that we need to have multiple retrospectiv...

Plastic surgeons countdown first full facial transplantation

...ransplantation, perfect our technique and visually confirm that a facial tissue flap is a match when covering severe burns and other trauma." Although traditional methods for facial reconstruction, which include skin grafts and flaps, are reliable and effective techniques for reconstructing the face, they m...

Aging cells, aging body: Fresh evidence for a connection

...divy said. "But until now, no one has been able to confirm that they exist in appreciable numbers in old animals." So the Brown team began to study aging animals ?baboons living on a research preserve that ranged in age from 5 to 30. In human years, that age range is roughly 15 to 90. Veterinarians took sm...

Faults in newly discovered breast stem cells may lead to tumours

...s now under way on excised human breast tumours to confirm the findings derived from the mouse model. The research team is from the WEHI Group of the Victorian Breast Cancer Research Consortium, which is funded by the Victorian state government through the Cancer Council Victoria. ...

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