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Tag: "confirm" at biology news

Studies find general mechanism of cellular aging

Three separate studies confirm a gene that suppresses tumor cell growth also plays a key role in aging. The researchers found increasing concentration, or expression, of the gene p16INK4a in older cells; these aging cells worked poorly compared to young cells and remembered their ...

First major study of mammalian 'disorderly' proteins

...arge numbers from the more structured proteins and confirm their roles in the cell," Kriwacki said. "Our new technique selectively concentrates the IUPs that are involved in regulating functions in the cell and transmitting signals within them." Unlike the classic description of proteins described in scie...

Sports cheats beware -- new test detects previously undetectable drug

...ar molecule is present ?in this case synacthen. To confirm that the immunological purification has pulled out synacthen, the protein is then subjected to a further two-stage test ?chromatography separation and mass spectrometric analysis. This lets scientists produce a chemical fingerprint of the molecule ?a...

Knockout Mouse Project

...for this study. Researchers hope to catalogue and confirm the functions of these genes and identify the disease consequences if these genes are defective. Since human and mice genes are similar, it is hoped that by inactivating mouse genes, one-by-one, the altered mice will yield clues about the function o...

Key to lung cancer chemo resistance revealed

...tive protein, he said. The researchers plan to confirm their findings with a larger set of samples and then to screen for appropriate drugs. Funding for the study was provided by the National Cancer Institute Lung SPORE (Specialized Program of Research Excellence), National Heart Lung and Blood Institu...

LSU professor discovers new species

...ant genetic variations. These traits combined to confirm the original hypothesis that the lizard was, in fact, an entirely new species. Austin spent the entire summer of 2006 in New Guinea, his geographical area of expertise, conducting fieldwork with graduate students. He is currently working on researc...

Genetic study of Neanderthal DNA reveals early split between humans and Neanderthals

..., the scientists performed a variety of studies to confirm that the vast majority of the human-like sequence in the library was indeed Neanderthal and not just contamination from human bone collectors and laboratory workers. The researchers then verified the authenticity of the Neanderthal sequence by comp...

Biologists probe the machinery of cellular protein factories

...ecular Biology of RNA at UCSC. "Our latest results confirm that the ribosomal RNA is really the key to ribosome function. The proteins are also involved, but more peripherally," he said. To make a new protein, the genetic instructions are first copied from the DNA sequence of the gene into a messenger RNA...

MIT's molecular sieve advances protein research

... even though no one has been able to unequivocally confirm this model in gel-based experiments. The MIT researchers were, however, able to confirm Ogston sieving in the nanopore sieves. "This is the first time anyone was able to experimentally co...

Spelling out cancer on the nanoscale

...allel, traditional Western blots were performed to confirm BCL-2 and MYC levels. "Our strategy can be used to repetitively and quickly assess the levels of oncoproteins in cancer cells grown in the laboratory and in human patients," says Felsher. "It may prove useful for the early detection of cancer, a...

Resistance and genetic sensitivity to sleeping sickness

...hese mutations and the disease necessitate work to confirm this in different populations and environments. New investigations, particularly in genetic epidemiology, are currently being put into operation in order to check up on possible effects of genetic predisposition already observed. The results obtained...

Research suggests beta agonists may alter the immune system

...disease. "Although further research is needed to confirm that these findings occur in the human body, our research points to an important means by which the immune system is regulated by both therapies and the hormonal system," Penn said. "From an asthma management standpoint, these studies further emphasi...

Adolescent but not adult hamsters are more aggressive on low dose of fluoxetine

...hor Kereshmeh Taravosh-Lahn, BA, says the findings confirm that juvenile and adult brains are different. Thus, she says, "It is unwise to expect a drug to work the same in juveniles as in adults." Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), is the only medication approved to treat dep...

Fighting like a girl or boy determined by gene in fruit flies

...tute of Molecular Pathology in Vienna. The results confirm that a gene known as "fruitless" is a key factor underlying sexual differences in behavior. The findings mark a milestone in an unlikely new animal model for understanding the biology of aggression and how the nervous system gives rise to different b...

Critical hearing gene helps send auditory messages to brain

...heir current study provides additional evidence to confirm that notion. They now report that otoferlin activity in the cochlea occurs only in the inner hair cells, where it concentrates in the ribbon-associated synaptic vesicles. They also found that the otoferlin protein binds calcium and interacts with ...

Gene chip technology shows potential for identifying life-threatening blood infection

...rful antibiotics, even before laboratory tests can confirm the diagnosis. But this practice invariably leads to the inappropriate treatment of many patients who have life-threatening, uncontrollable inflammation without an underlying infection, a condition also common among ICU patients. New research now ...

West Australian fossil find rewrites land mammal evolution

... discoveries of fossils in Australia are needed to confirm this." ...

Jefferson scientists find aging gene also protects against prostate cancer development

...rostate specific antigen (PSA) levels were used to confirm this. Rising PSA levels are frequently an indication of prostate cancer growth or recurrence, whereas falling levels indicate tumor shrinkage. “This study shows that there is potentially new opportunity for these cancer patients with drugs that re...

Scientists work to identify genes that contribute to early heart attack risk

...part two of the study, the scientists will work to confirm their findings by determining if any genetic factors associated with early atherosclerosis in PDAY subjects also predict atherosclerosis in living participants of the $68 million MESA study. This 10-year multi-center study began in 2000 and is workin...

Scientists identify 36 genes, 100 neuropeptides in honey bee brains

...pmental stages. Future work will no doubt find and confirm more of the brain's peptides. "The potential of our blended technology approach to facilitate discovery of these peptides is not only significant for advancing honey bee research," the researchers wrote, "it demonstrates promise for neuropeptide di...

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