ASU researchers 'wire' DNA to identify mutations
...current of a single DNA molecule. For a proof of concept of the potential for measuring SNPs, the group used DNA of 11 or 12 bases in length dissolved in a physiologically relevant saline solution. From one electrode tip, a small current, or bias is used to probe the internal electronic states of DNA. By...Federal grant funds research on novel HIV therapy
...logous to HIV. This study aims to provide proof of concept for human trials under Project 4. Project 4, led by Pablo Tebas, M.D., of the Department of Medicine at the University of Pennsylvania Medical School, will be a phase 1 (safety) trial of the NK-1R antagonist aprepitant (trade name Emend) in adults ...New book highlights world's borderless conservation areas
...the Waterton-Glacier International Peace Park, the concept has expanded to more than 100 parks and protected areas throughout the world. Transboundary conservation areas, or TBCAs, offer multiple benefits, both internationally and at regional and local levels. They can reduce tensions between countries and ...Genetic testing still smart choice, despite uncertainties
...h diagnosis occurs, researchers say. "Our pathway concept may help to explain the observed outcomes during preimplantation diagnosis," said Kenneth Drury, Ph.D., director of the UF IVF and Andrology Laboratory and a clinical professor in the College of Medicine who was one of the researchers. "When we biops...Sperm trading can resolve hermaphrodite mating conflicts
...y sooner than did control pairs. This supports the concept of sperm trading, where mates negotiate mating roles in order to balance sexual interactions. ...Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer
...l lines and in a mouse cell control. In a proof of concept study, they found evidence that the alternating LHRH and lytic peptide on the ironoxide particle was effective at killing cancer cells, suggesting that the cell-killing peptide worked best when it came in direct contact with the cell membrane. "It is...K-State researchers study insects' immune system
...t to the next person it bites poses an interesting concept for researchers. For the disease to spread, it has to survive for a certain period of time in the mosquito. The question is, how does the pathogen survive? For a disease like malaria, the parasite has to live in an insect's blood for part of its lif...Student scientists create living bacterial photographs
...M competition , check it out! Some pictures of the concept they'll use for their bacterial 'camera'. Using Petri dishes full of genetically engineered E. coli instead of photo paper, students at The University of Texas at Austin and UCSF successfully created the first-ever bacterial photographs. Their wo...NC State researchers redesign life for Mars and beyond
...itions that one might find on Mars." Now that the concept of inserting a single gene from an extremophile into a plant has been proven, the researchers are working to insert associated genes in hopes of providing evenmore extreme-temperature protection to plants. And, they're involving more great minds toco...Researcher says flu responders can learn from 1918 epidemic
...gins said that survival might depend on the simple concept of community planning. In studying the metropolitan areas around the state of Pennsylvania, Higgins found that the areas that suffered the lowest mortality rates included Bethlehem, which benefited from the resources provided by the then-prosperou...Volunteers sought for avian flu vaccine study
...lu virus isolated last year. "It's similar to the concept of the regular flu vaccine that people get every year, but it's targeted to this novel type of flu," Edwards said. Because the study is beginning at the start of this year's influenza season, all participants will be given this year's licensed influ...Eleven gene 'signature' reliably predicts cancer prognosis
The rather new concept of "tumor stem cells" maintains that a rare, stem cell-like population of cancer cells exists among the mix of other cells found in a tumor and that these tumor stem cells are responsible for tumor progression and metastasis. In a revolutionary study...Vaccine targets tumors where they live
...d for improving systemic anti-tumor immunity. This concept has been suggested in mouse models but had not established in the clinical setting. The data represent the first clinical trial to directly inject a vaccinia virus expressing the B7.1 costimulatory molecule into humans with melanoma. The researchers...New law for resolution allows unprecedented sharpness in fluorescence microscopy
...pletion (STED) microscopy, a physically consistent concept for breaking the diffraction limited resolution limit in fluorescence microscopy, and then verified it in experiments. Unlike in the light microscopes conceivable so far, in a STED microscope, the relevant focal fluorescence spot can, in principle, b...Monkeys understand numbers across senses
...tes that numerical perception is truly an abstract concept and not just a function of a particular sense, said the researchers. The experimental approach also will lead to further studies exploring whether human infants, before they have a verbal capacity, understand similar abstract numerical concepts, they...From a Few Wild Ancestors, a Citrus Cornucopia
...rms. The research also supports the generally held concept that most familiar citrus fruits -- including oranges, grapefruits, and lemons -- are actually hybrids. A Chosen Few Part of this can be explained by the fact that citrus, which is native to Southeast Asia, hybridizes readily. “Citrus has been dom...Change in gene may be underlying molecular defect in some colorectal cancers
...m and Women's Hospital, both in Boston, review the concept of the field defect (also called the field effect or field cancerization). They also raise several questions about how these findings may affect related areas of research, such as approaches to chemoprevention and "whether the reversal of DNA methyla...Virulizin granted orphan drug status in Europe
...tion awarded a prize to a promising gillnet design concept using glowing ropes and stiffer nets that may help cetaceans see gillnets in order to avoid them and to escape if they do accidentally swim into the net. Species and populations designated in the report as among the top priorities for investment of ...Novel targets found for the development of drugs to complement, or replace, statins
...tion awarded a prize to a promising gillnet design concept using glowing ropes and stiffer nets that may help cetaceans see gillnets in order to avoid them and to escape if they do accidentally swim into the net. Species and populations designated in the report as among the top priorities for investment of ......tion awarded a prize to a promising gillnet design concept using glowing ropes and stiffer nets that may help cetaceans see gillnets in order to avoid them and to escape if they do accidentally swim into the net. Species and populations designated in the report as among the top priorities for investment of ...