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Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily

...Journal, will provide vital data to conduct future computer simulations of HIV dynamics to help further drug discovery and prevent deadly infections. “We found that HIV fusion peptide dramatically decreases the amount of energy needed to bend a cell-like membrane,” said Stephanie Tristram-Nagle, associate re...

Math that powers spam filters used to understand how brain learns to move our muscles

A team of biomedical engineers has developed a computer model that makes use of more or less predictable...e tune what they exclude from your in-box. The computer model, Shadmehr says, almost precisely duplicates the results of experiments that tested the ability...

Modeling the restless brain

... approach -- which involved creating a large-scale computer model of the brain of a macaque monkey -- they dem...) of regions in the human brain are connected. The computer model created by Sporns and Honey suggests that this very pattern of connectivity is crucial to gene...

Simulations unravel outer membrane transport mechanism

...y L. Brian Stauffer Using X-ray data and advanced computer simulation and visualization software, researchers at the University of Illinois have painstakingly modeled a critical part of a mechanism by which bacteria take up large molecules. Their findings provide a rare window on the complex interplay of pro...

Envisat captures first image of Sargassum from space

...inciple behind Grid computing is that anything one computer can do, a pool of computers can do faster and better, enabling the solution of massively complex tasks beyond the capabilities of a single machine or local network. By using Grid technology, Gower and King intend to compute 5-years worth of MERIS...

Largest synthetic gene ever built offers insights into anti-malarial drug resistance

...hen "back translated" the protein sequence using a computer program to change the parasite gene sequence − which combines nucleotide base pairs in a way that is found in no other life form − into one that could be "read" by yeast. The yeast are then able to produce the PfMDR1 protein, in its proper sequen...

Alzheimer's disease to quadruple worldwide by 2050

... the researcher created a multi-state mathematical computer model using United Nations population projections and other data on the incidence and mortality of Alzheimer’s. ...

Stroke study sheds light on left-right brain divide

...learning rules linking the colour of a symbol on a computer screen with a movement to the left or right. All the participants made mistakes during the task, but it was those with right-brain damage who most frequently failed to spot their errors and had difficulty keep track of the changing task rules. The gr...

Exploring the dark matter of the genome

...Francisco State University. "We used a pipeline of computer programs to analyze the raw sequence data, in search of genes. We identified patterns of codons that might indicate a gene splice-site or a promoter, for example. We mapped experimentally derived evidence of messenger RNAs back to the matching hetero...

Research finds that circadian rhythms dominate all life functions

... in 98 to 99 percent of all genes through advanced computer algorithms. Most of these genes have never been previously reported as changing their expression level in a daily cycle. Some of these genes, considered "housekeeping," have been used as a stable reference platform in gene expression studies. "A...

Helping chlorine-eating bacteria clean up toxic waste

...ene Network Sciences (GNS), a firm specializing in computer simulation of biochemical processes, to create computer models of the inner workings of the bacterium. The project is funded by a three-year, $381,000 grant...

Male circumcision overstated as prevention tool against AIDS

... infected and killed. It is not surprising that computer models rarely show the virus reaching epidemic proportions; it is very hard to transmit this illness heterosexually. Only when model building researchers introduce a highly sexually active infected subset of “prostitutes” to their mathematical models...

Scientists close in on missing carbon sink

...terrestrial carbon sink, scientists have turned to computer models that combine worldwide wind patterns with m...rne carbon dioxide concentrations generated by the computer models. The scientists found that most of the models significantly underestimated the airborne conce...

'Virtual Patient' to simulate real-time organ motions for radiation therapy

...ct involving the 3-D VIP-Man, which is an advanced computer model that simulates in 3-D how radiation affects the organs and tissues in the human body. "Live patients are not static beings, and a moving organ such as the lung or heart is a main concern in radiation treatment or imaging of tumors that are a...

Arctic ice retreating more quickly than computer models project

...ster rate than projected by even the most advanced computer models, a new study concludes. The research, by sc...ating more rapidly than estimated by any of the 18 computer models used by the Intergovernmental Panel on Climate Change (IPCC) in preparing its 2007 assessmen...

Technique monitors thousands of molecules simultaneously

...essing thousands of minuscule electrodes on a tiny computer chip that do chemical reactions and yield molecule...enough. But, with an electrochemically addressable computer chip, provided in great abundance by one of his sponsor's, CombiMatrix in Seattle, Moeller saw a way...

The sound of proteins

...opular compositions. They are currently piloting a computer program, written by a collaborator Frank Pettit, w...es. Further examples of converted proteins and the computer program are accessible for online use [ www.mimg.ucla.edu/faculty/miller_jh/gene2music/home.html ]. ...

Role of noise in neurons

...(1ìm is one millionth of a meter). Although, as in computer chips, this miniaturization economizes on space and energy, it increases the noise introduced by thermodynamic fluctuations in a neuron's voltage-gated ion channels. Axons use action potential (AP) to transmit information fast and reliably to synapse...

New technique will produce a better chromosome map

...chromosomes. With so many crisp images to analyze, computer algorithms can accurately calculate the number, sh... graduate research assistant Mert Dikmen, who uses computer vision technologies under the supervision of Beckman Institute professor Thomas Huang to analyze the...

New Brandeis research sheds light on memory by erasing it

...hat are necessary for a memory molecule. Like a computer whose electronics change with the addition of new information, molecular activity in the hippocampus, where memory is stored in the brain, changes as memory is being stored. In this study, Lisman and his colleagues showed that they could saturate the...

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