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Tag: "computational" at biology news

One species, many genomes

... days, is already available. Still missing are the computational algorithms to interpret the anticipated flood of data....

Nicotine rush hinges on sugar in neurons

...aid Lin Chen, associate professor of molecular and computational biology at USC. Many existing theories, which do not consider sugar’s role, are probably incomplete, Chen said. The debate over how signals pass from the outside of a cell to the inside is a long-standing one. Some researchers had suggested tha...

Modeling the restless brain

...ntaneous activity of the brain at rest. With their computational approach -- which involved creating a large-scale ...eural networks are structured are available. A computational model of the human brain would help researchers better understand where the observed resting state f...

Simulations unravel outer membrane transport mechanism

... take an extensive amount of time and considerable computational effort. The researchers addressed two key quest...dent transporter, Gumbart said. “As we get more computational power, we’re looking less at single proteins and more and more at the interaction of proteins,” he s...

Migration alert -- How tumor cells home in on the lymphatic system

...the tumor-lymphatic microenvironment and developed computational models to calculate the gradients of the signaling molecule. The study provides the first evidence that tumor cells can both produce and use the same signaling molecule, and it highlights the significance of the biophysical environment in the vic...

New findings challenge established views on human genome

... at least when examined by current methods used by computational biologists. According to ENCODE researchers, t...e experiments and then analyze them using multiple computational methods,” said Elise A. Feingold, Ph.D., program director for ENCODE in NHGRI’s Division of Extramur...

'Virtual Patient' to simulate real-time organ motions for radiation therapy

...ir energy on respiratory function. "Using advanced computational tools, it is possible to simulate lung movement; however, not in real time," De said. "For effective radiation therapy, physics-based real-time performance offers the ultimate solution." The key challenge in this project is to develop the algorith...

How to steer a moving cell

... ?biologists, chemists, proteomics researchers and computational biologists who can integrate large data sets ?have applied a global approach to analyzing how proteins regulate cell movement." The research team’s profile of chemotactic cells is the first and most comprehensive catalog of proteins that exists to...

DOE JGI sets 'gold standard' for metagenomic data analysis

...and microbial communities through a combination of computational and experimental methods," said Konstantinos Mavro...ot least, it will stimulate the development of new computational tools and approaches for studies of microbial communities." In a shotgun sequencing process, the ...

York mathematician probes geometric route to combat viruses

...Trust Award to build up a group of mathematicians, computational biologists and biophysicists to address a portfolio of projects arising from these results.? This grant will enable Dr Twarock to expand her group and fund three postdoctoral positions and four PhD students. The group will collaborate closely with ...

MIT's ocean model captures diversity of underwater forests

...c diversity of marine microbes, recent advances in computational capability and a simple recognition of his own bias. "Physicists, like myself, have a bit of a reductionist view. We often shy away from the complexity of the real world in our models and prefer to reduce things to the simplest case with fewest fa...

Bones in motion: Brown scientists to create new 3-D X-ray system

...t creating the imaging technology will be a mainly computational challenge, so funding will also support substantial software development. Brown faculty and students are already at work on pilot projects to visualize pigs walking, birds flying and frogs jumping, using seed funds from Brown's Office of the Vice ...

Noise echoes in cell communications

...a thrust to ultimately offer a doctoral program in computational and integrative biology on the Camden campus. "We talk about biological problems and apply mathematical principles," says Martin, who believes the development of the Systems Biology Institute in Camden, which will be managed by Rutgers-Camden, will f...

Sandia researchers take new approach to studying how cells respond to pathogens

...rrent commercial imaging technologies Powerful computational modeling that allows researchers to make sense of ...s the integrated platform, biological reagents and computational models developed under this project have applicability beyond infectious disease research. These tec...

2 brains -- 1 thought

...ng with many unknown quantities and requires great computational power. Already in a network of 1000 neurons (where each neuron can be connected to any other) there are a million possible contacts between any two neurons and consequently an unimaginably large number of possible networks. Each combination can have ...

Beyond the DNA: Chemical signatures reveal genetic switches in the genome

...d enhancers. These findings enabled us to generate computational algorithms that identified hundreds of novel genomic regions with regulatory potential." Moreover, says Heintzman, this 'histone code' was able to accurately distinguish between promoters, from which gene transcription is directly initiated, and enha...

MIT model helps researchers 'see' brain development

...ce Laboratory (CSAIL) and HST, and director of the computational core at the HST Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH). The team started with a collection of MR images from 11 developing brains, provided by Ellen Grant, chief of pediatric radiology at MGH and the Martino...

Mimicking how the brain recognizes street scenes

...vern Institute for Brain Research at MIT applied a computational model of how the brain processes visual information to a complex, real world task: recognizing the objects in a busy street scene. The researchers were pleasantly surprised at the power of this new approach. "People have been talking about comput...

Map predicting spread of avian flu

...al Biology, arrives at these conclusions through a computational (or mathematical) modeling method, an approach which has already proved its worth in the analysis of infectious diseases such as the 2001 foot-and-mouth outbreak in the UK. The method can estimate the key parameters which determine the spread of high...

Scientists map key landmarks in human genome

... gene microarray studies followed by sophisticated computational data analysis to pin down the nucleosome locations...of the analysis involved processing the data using computational algorithms devised by Dana-Farber faculty member X. Shirley Liu, PhD, and her postdoctoral fellow Ju...

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