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Tag: "compounds" at biology news

Testes to incubate stem cells

... cultures could also prove an ideal system to test compounds that might affect sperm-production such as endocrine disruptors or therapeutic drugs. ...

Heart-healthy compound in chocolate identified

...hin meets five previously established criteria for compounds that directly cause improved circulation. In the o... these findings point to epicatechin as one of the compounds found in cocoa that has beneficial impacts on cardiovascular health. ...

Researchers use dirt to stay one step ahead of antibiotic resistance

... ways to survive or resist the toxic antimicrobial compounds produced by their neighbors," said Wright. "Their ... classes of antibiotics, regardless of whether the compounds were naturally produced, semi-synthetic, or completely synthetic. Researchers also found that the...

Scientists a step closer to protecting world's most important crop

...ible that more specific, environmentally friendly, compounds to combat rice diseases could result from this research." Last year scientists from The University of Exeter helped to complete the sequence of the rice blast fungus genome, which has aided the current research. ...

Sweet 'water taste' paradoxically predicts sweet taste inhibitors

...nhibitor. To understand how sweet 'water taste' compounds could act both as a sweetener and as a sweet inhibitor, collaborators Marcel Winnig, Bernd Bufe, and Wolfgang Meyerhof of the German Institute of Human Nutrition conducted a series of molecular studies using cultured cells expressing the human sweet ...

New compound stops brain cell degeneration in Alzheimer's disease

...thwestern researchers found that 188WH and related compounds slowed or reversed the progression of the neuroinflammatory cascade and reduced human amyloid beta-induced glia activation in a mouse specially designed to develop many of the signs of Alzheimer's disease, including neuroinflammation, neuronal and sy...

Defective immune system response to smallpox vaccine detailed in new study

...13. Although no such drugs are currently marketed, compounds that can neutralize IL-4 and IL-13 are under study as possible asthma and allergy treatments, Dr. Leung says, and might also be applied to eczema vaccinatum treatment. Smallpox vaccine, which is made with live vaccinia virus (a close relative of th...

Potential vaccine developed for deadly leishmaniasis disease

...ent in medical circles. Carbohydrates are chemical compounds that include sugar and are made from units linked together like beads on a chain. "This is the first and only carbohydrate vaccine candidate against this disease," Seeberger stated. "This candidate vaccine brings something new to the table and may b...

Study in Science holds promise for a new approach to drug therapy

...periments, for example, have found that one of our compounds can make morphine 11 times more potent," said Smrc...get long enough to have the desired effect. Of the compounds found through the screen, one, called M119, had a high enough affinity for the hotspot to be chosen ...

New compound protects against liver cancer

...o be effective at doses 100 times lower than other compounds known to prevent cancer in people. Because of its ...ompound that belongs to a class of cancer-fighting compounds called triterpenoids under development by Dr. Michael Sporn and other study co-authors at Dartmouth ...

New possibilities to fight pests with biological means

...ynthase, an enzyme forming the sesquiterpene scent compounds that are released by the plant and attract wasps t...s, TPS10, produced the exact bouquet of nine scent compounds that was released by the damaged corn plant. To demonstrate that TPS10 is indeed the important gene,...

Curry and cauliflower could halt prostate cancer

...e been investigating intervention options based on compounds found in edible and medicinal plants. They have ha...ow combining the conventional therapies with these compounds as alternative, supplementary or complementary medications. For Kong's study, researchers used mice...

Gene-specific Ebola therapies protect non-human primates from lethal disease

...se and clear the virus." Working with a class of compounds known as antisense phosphorodiamidate morpholino oligomers, or PMOs, the team first performed a series of studies to identify PMOs that demonstrated activity against Ebola virus. Next, three of the PMOs were tested in mice, both individually and in c...

New brain hormone puts brakes on reproduction

...taining GnIH also have receptors for estrogen-like compounds such as estradiol, the combined evidence suggests that GnIH is a direct inhibitor of GnRH. Because the brain cells producing and secreting GnIH send their axons into many areas of the brain, GnIH may have other effects on the brain, too. "Though we...

Anti-HIV drug has potential to prevent transmission in women

...cal School, both in Providence, RI. "Analyzing the compounds that already have been shown to be successful HIV treatment drugs, and evaluating them for their potential to prevent transmission of infection is an innovative approach that shows great promise." Published in the Feb. 28 issue of the journal AIDS, ...

Georgia Tech accelerates drug discovery with new IBM supercomputing cluster

..., enabling drug developers to reduce the number of compounds they must screen by a factor of 10." The 1000-node Cluster 1350 system built on IBM BladeCenter® systems and powered by dual-core AMD Opteron TM processors is capable of performing more than 8.5 trillion calculations per second, which would place i...

New antimicrobial compound adheres to skin to promote healing

... kill those drug-resistant bacteria and fungi with compounds that cleanse wounds while being gentle on the tissue." Combining Tricide with a bioadhesive came about as a result of collaboration between Ritchie and Tony Capomacchia, an associate professor in the College of Pharmacy who specializes in the formu...

Computer simulation hints at new HIV drug target

...aiwan University hope to discover and develop real compounds that can regulate flap motion in this manner. Lin is currently assembling a team of researchers for this project. In the meantime, while Perryman is completing a postdoctoral fellowship, he is learning about protein engineering with Mayo, so that he ...

Major WHO study concludes calcium supplements can reduce complications during pregnancy

...aiwan University hope to discover and develop real compounds that can regulate flap motion in this manner. Lin is currently assembling a team of researchers for this project. In the meantime, while Perryman is completing a postdoctoral fellowship, he is learning about protein engineering with Mayo, so that he ...

Drug resistance may travel same path as quorum sensing

... and many different drugs will be pumped out. "It compounds the problem," said Zechiedrich. Her findings are a step toward understanding the mystery surrounding drug resistance, she said. In her work, she found that two of these "pumps" or transporters ?AcrAB/TolC and NorE ?actually export as yet unidentifie...

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