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Tag: "compounds" at biology news

Katrina floodwaters not as toxic to humans as previously thought, study says

...mponents: benzene, toluene and ethylbenzene. These compounds were somewhat elevated in comparison to typical st...waters, Pardue says. The waters contained chemical compounds from aerosol paints, insecticides, caulking compounds, rubber adhesives and other common substances,...

Membrane research opens window to benefits for plants, humans

...developed into a diuretic drug. By the same token, compounds that stabilize the closed structure could be used in cancer treatment." Tajkhorshid and Yi Wang, a biophysics graduate student at Illinois, conducted the molecular simulations using VMD and NAMD software developed in their Beckman lab, which is an N...

Compound from marine bacteria shows potential as multiple myeloma therapy

...omib (Velcade tm) was the first in a new class of compounds in multiple myeloma. NPI-0052 is a novel proteasome inhibitor with a chemical structure and action that is distinct from bortezomib, and has the promise of being even more effective for patients," says Kenneth Anderson, MD, director of the Jerome Li...

New battery technology helps stimulate nerves

... medical devices. "It turns out the organosilicon compounds are really good for improving lithium battery tech...is the heart of the battery. The new organosilicon compounds developed by the Wisconsin chemists, says West, have numerous advantages over traditional lithium ba...

Phenolic compounds may explain Mediterranean diet benefits

Phenolic compounds in olive oil, which have antioxidant, anti-inflamm...efit of an olive oil with high content in phenolic compounds on endothelial function in vivo," Dr. Pérez Jiménez said. After fasting overnight, the participants...

Mutations in the BRAF gene predict sensitivity to a novel class of cancer drugs

...tion, by re-analyzing the data on more than 42,000 compounds tested by the National Cancer Institute against a ...tors were able to identify a small number of other compounds that also selectively inhibit tumors that have the BRAF mutation. While the mechanism of action of s...

Biologists discover new pathway into plant cells

... delivery vehicle, a completely new way to deliver compounds inside of a plant cell and target specific genes. This is a new and unprecedented insight into how plants can work." The process of proteins getting inside of cells and affecting their behavior is common in animal cells, the scientists said. For ins...

Antibacterial coatings cut infection rates

...Wales developed synthetic analogues of the natural compounds and discovered that these chemicals also keep synt... don't kill bacteria. This means that the furanone compounds should not cause bacterial resistance, according to microbiologists. "When bacteria sit on the surf...

Hot-spring bacteria flip a metabolic switch

...to fix nitrogen, converting nitrogen gas (N2) into compounds that are useful for cell growth. The study, published January 30 in the early online edition of the Proceedings of the National Academy of Sciences, is the first to document an organism that can juggle both metabolic tasks within a single cell at hi...

Pair of studies offer new clues to combat antibiotic resistance

...says Walker. Her lab will soon begin screening for compounds that can block this important chemical pathway, she says. Gram-positive bacteria include anthrax and other strains that cause upper respiratory infections and sepsis. In comparison to gram-negative bacteria, they are generally considered easier to c...

Pain killer fights breast cancer by targeting key enzyme

...onduct animal studies to learn how effective these compounds are when they are actually inside the body and what the potential side effects may be." ...

Enzyme inhibitors block replication of SARS virus

...aiwan have been looking at other Liponavir-related compounds for similar blocking effects. During these experim...r or any of the target compounds. These organic compounds are called benzotriazole esters. The esters entered the SARS protease site, formed an intermediary c...

MIT chemist discovers secret behind nature's medicines

...s to generate a large family of medically valuable compounds called halogenated natural products. The question was, how do they do it? Chemists would love to have that enzyme's capability so they could efficiently reproduce, or slightly re-engineer, those products, which include antibiotics, anti-tumor agents...

Mining for gems in the fungal genome

...t may speed the ongoing quest for medically useful compounds in fungi. By manipulating a single fungal prote...eating dozens of secondary metabolites, a class of compounds that make good drug candidates. Already, analysis of one subset of these genes has revealed that th...

Researchers get neurons and silicon talking

...ing tissue of individual neurons and the inorganic compounds of silicon chips. It was a difficult task. "We had a lot of problems to overcome," says Vassanelli. "And we attacked the problems using two major strategies, through the semiconductor technology and the biology." With the help of German microchip c...

Marijuana-like compounds suppress the immune response

... group of chemicals that include marijuana. These compounds bind to and activate the body's cannabinoid recept...ls. They found that treating the blood cells with compounds that bind to CB2 suppresses the migration of the cells. When they examined the cells, they discover...

Fruit fly's beating heart helps identify human heart disease genes

...mans, researchers can then not only test different compounds or drugs, but do so much quicker than in other mammal models of disease. "These findings have the potential to change the way we do genetic screening to identify candidate disease-causing genes," Rockman continued. "Never before have we been able to...

Marine mammals are on the frontline of failing ocean health

...ect that these diseases are linked to brevetoxins, compounds produced by specific algal blooms. Neurotoxic shellfish poisoning and other acute effects of consuming brevetoxins are not new to scientists. But Bossart and his colleagues' work on manatee die-offs associated with red tides shows that inhalation o...

Flesh-eating bacteria escape body's safety net

...ause they release "nets" composed of DNA and toxic compounds to entrap and kill invading bacteria. In the current study, the UCSD scientists proved that disease-causing Strep release an enzyme that degrades these DNA nets, thereby allowing the organism to escape the neutrophil net and spread in body tissues. ...

Relic of life in that Martian meteorite? A fresh look

...990s a great debate has raged over whether organic compounds and tiny globules of carbonate minerals imbedded in the Martian meteorite Allan Hills 84001 were processed by living creatures from the Red Planet. The materials have been under intense scrutiny ever since. Scientists at the Carnegie Institution's ...

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