compound 2 7

Tag: "compound" at biology news

Scientists stop autoimmune disease without shutting off immune system

...PV patients. In mice, the researchers used a known compound to turn off the signals that trigger skin damage without suppressing the immune system. Similar drugs being developed for human use could offer a potential treatment for PV, the researchers said. The results appear in the Aug. 22 issue of Proceeding...

Cigarette smoke blocks cell repair mechanism, University of Florida study shows

...o demonstrate in normal-like epithelial cells this compound produced a transformation. Cigarette smoke condensate contains more than one compound, so the UF experiment is more similar to the way any human being would be exposed to the carcinogens. It mimics the human situation more closely."...

Research reveals inner workings of immune system 'thermostat'

.... So immune system cells let loose another protein compound to cool down the immune response. Precisely how ...eam show that the "cool" anti-inflammatory protein compound known as Interleukin 10 is activated by Interferon-γ, a class of proteins secreted by a class of whi...

Injection may prevent infertility in men receiving cancer chemotherapy

...01 is a Tellurium-based non-toxic immunomodulatory compound developed and synthesised by us. Tellurium is a transition element with similar properties to Selenium, which is also known to have many beneficial effects." Knowing that AS101 had been shown to have chemoprotective effects in both animal and human...

Finding paves way for better treatment of autoimmune disease

..., that is the most natural way, if we can find the compound in our bodies that can do the job," Dr. Iwashima says. He theorizes that this natural substance helps destroy non-regulatory T cells when the body gets too many, say after fighting a big infection, and that it may not work well enough in people with ...

UC Davis researchers reveal apples' protective ways

...by exposing them to tumor necrosis factor (TNF), a compound that usually triggers cell death and promotes inflammation via a mechanism called the "nuclear factor (NF) kappa B pathway." This pathway involves chemical signaling between cells. The apple extract was able to protect the cells from the normal letha...

Microbes transform 'safest' PBDEs into more harmful compounds

...n transform the most commonly used flame retardant compound in the United States into more toxic forms that could be harmful to humans, according to a new laboratory study published today on the Web site of the American Chemical Society journal, Environmental Science & Technology . The study is scheduled...

New compound reduces stroke damage

A group of German scientists has synthesized a new compound that dramatically decreases the damage to neurons ...experiencing stroke symptoms. "We developed a lead compound that strongly inhibits FKBP38 leaving other brain FKBP almost untouched under certain conditions," s...

Researchers unveil strategy for creating actively-programmed anti-cancer molecules

... in animal models. The study showed the new hybrid compound remained in circulation for a week. In comparison,...sed the unique assembly strategy to create a novel compound to combat metastatic breast cancer. Breast cancer can be a treatable disease, but only if diagnose...

NYU researchers decorate virus particles, showing potential to enhance MRI capabilities

... large number of gadolinium chelates--the chemical compound used in MRI contrast agents --on the surface of the viral particles. This resulted in the generation of a very intense signal when Wang imaged their samples in a clinical MRI scanner. "Our work validates some hypotheses in the field of Magnetic Reso...

A sweet solution for Alzheimer's disease?

...shouldn't be a problem with scyllo-inositol. "This compound works by a different mechanism and doesn't involve immunizing a patient with his own protein, which was probably the origin of the allergic reaction to the vaccine," the researcher said. Another complication with previous attempts to treat Alzheime...

Science captures the essence of fruit

...ion however can produce large amounts of a desired compound at a low cost and with little environmental impact...se in the wild, the resulting flavour or fragrance compound has exactly the same molecular make-up. It is, as the scientists say; "Nature Identical". While th...

Scientists take 'snapshots' of enzyme action

...ofactor, and the enzyme plus the cofactor plus the compound to be oxidized (the substrate). "These crystal structures give step-by-step snapshots of different stages of the catalytic action," Swaminathan says, "and reveal a mechanism that is different from what had been known about this process." Previously...

Drug dials down the energy within cells, UM researchers find

...ann Collegiate Professor of Chemistry at U-M. "Our compound works more like a volume control, so we're able to...etails of Bz-423's activity. They learned that the compound targets an enzyme inside mitochondria, the energy factories of cells. The specific enzyme, F1F0-ATPa...

UBC researchers find stroke death channel

...channel malfunction. Scientists can then develop a compound to block brain cell hemichannels from opening, says MacVicar. Therapies for stroke patients may be available within five to 10 years, he adds. ...

Gardenia fruit compound starting point for diabetes therapy

... an inhibitor could theoretically represent a lead compound for agents aimed at improving beta cell function in type 2 diabetes." Study coauthor Chen-Yu Zhang's familiarity with traditional Chinese medicine led the team to consider the extract of Gardenia jasminoides Ellis fruits. Pancreas cells taken from n...

Orange, grapefruit juice for breakfast builds bones in rats

...in citrus," he said. "So we need to find out which compound in citrus caused this." Patil suspects "limonoid,"a natural citrus compound, which has been increasingly studied for its potential to prevent various human diseases. Limonoids will be the next phase of the study, but there are at least 40 different ...

Light-sensitive photoswitches could restore sight to those with macular degeneration

...e of the photoswitch is a molecule - an azobenzene compound - that changes its shape when illuminated by light...K (potassium) channel, by attaching the azobenzene compound to a broken potassium channel, which is a valve found in nerve cells. When attached, one end of the ...

New angiogenesis finding may help fight cancer growth

..., and noticed that it turns on a gene that makes a compound called neurokinin-B, or NK-B. Aware that NK-B a...ved in blood-cell formation turn on the gene for a compound that is supposedly involved in regulating the nervous system?" The researchers searched for NK-B r...

Test reveals effectiveness of potential Huntington's disease drugs

...striatal neurons are oversensitive to glutamate, a compound that nerve cells use to communicate with each othe...ington's because it interacts with homocysteine, a compound that makes nerve cells more vulnerable to glutamate. Gabapentin and lamotrigine, both glutamate inhi...

1 2 3 4 5 6 7 8 9 10