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Tag: "compound" at biology news

Anti-cancer Compound In Beer Gaining Interest

A compound found only in hops and the main product they are u...ed the cancer-related properties of this flavonoid compound called xanthohumol about 10 years ago. A recent publication by an OSU researcher in the journal Phyt...

Student scientists create living bacterial photographs

...at ultimately controls the production of a colored compound in the bacteria. The Texas students, including Tabor and Aaron Chevalier, realized that after optimizing the pigments and agar growth media, these bacteria could be used to convert light images shined onto the bacteria into biochemical prints. To c...

Natural compound from 'pond scum' shows potential activity against Alzheimer's

A compound isolated from a cyanobacterium, a type of blue-gre...g structure, it could be many years before the new compound is tested as a drug candidate in humans, the scientists caution. In addition to Gademann, others inv...

Small molecule inhibitor of cholera discovered

... disease. They then showed that the most promising compound prevented cholera bacteria from setting up an infection when introduced into the digestive tract of mice. Since most disease-causing organisms use elaborate virulence factors such as toxins to do their damage, the new approach should be widely appl...

NIAID researchers show how promising TB drug works

...ow-growing M. tb, giving rise to optimism that the compound may be useful in treating both active and latent TB. (For information about the first clinical trial of PA-824, see June 14, 2005, NIAID press release: http://www3.niaid.nih.gov/news/newsreleases/2005/tb_pa_824.htm .) PA-824 must be chemically acti...

Seaweed yields new compounds with pharmaceutical potential

...ill the bacterium would be harmful to humans. The compound that was isolated in the greatest abundance -- nam...ly takes at least a decade from the discovery of a compound to the marketing of a new drug. If that does happen in this case, Fijian villagers and the Fijian go...

Polymer gel can block toxic leakage problem in gene therapy

... the viral escape problem in the form of a polymer compound already employed for wound healing and for drug an... After being mixed with a gene-bearing virus, this compound -- called poloxamer 407 -- undergoes a temporary phase change as its stiffens from a liquid to a gel...

Double trouble: Cells with duplicate genomes can trigger tumors

...The researchers treated normal breast cells with a compound that interfered with the final step of cell division, causing many of them to have the extra chromosome set. To make the cells more likely to become malignant, the researchers used cells that lacked a protective gene, p53 that is inactivated in many ...

Cattle grazing may help rather than hurt endangered species

... Their simulations show that climate change could compound these impacts, potentially, leaving endangered fairy shrimp and tiger salamanders without enough time to mature before their temporary aquatic environments disappear. "Consequently, land managers can play an important role in climate change impacts,...

Membrane research opens window to benefits for plants, humans

...rsity news release. "If we can identify a chemical compound that can close the aquaporins in the kidneys, this can be developed into a diuretic drug. By the same token, compounds that stabilize the closed structure could be used in cancer treatment." Tajkhorshid and Yi Wang, a biophysics graduate student at ...

Novel protein complex enables survival in hostile environment

...e organisms turn sulfate into sulfide, a corrosive compound or gas that smells like rotten eggs. Methanogenesis is a 2.7?.2-billion-year-old process and sulfate reduction originated at least 3.7 billion years ago on earth. "These two processes apparently cannot exist within one living cell, because the reduc...

Bare metal stents deliver gene therapy to heart vessels with less inflammation in animal studies

...gates initial benefits. The new technique, using a compound that binds in an extremely thin layer to bare metal surfaces, may have potential uses in other areas of medicine that make use of metallic implants. Cardiologists frequently treat heart disease patients now by using stents to expand partially blocke...

Compound from marine bacteria shows potential as multiple myeloma therapy

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sed...Dana-Farber, and senior author of the report. The compound will be moved into Phase I clinical trials in early 2006, say officials of Nereus Pharmaceuticals in...

New battery technology helps stimulate nerves

... Alumni Research Foundation, the new organosilicon compound technology is also being developed through a new start-up company, Polyron, Inc. The work to develop the new organosilicon compounds was funded by the National Institute of Standards and Technology, a federal technology agency that works with industr...

Federal grant funds research on novel HIV therapy

...mune cell cultures. They subsequently found that a compound that binds to the substance P receptor in immune cells inhibits HIV from entering its hiding place within immune cells. That compound, from a class of agents called neurokinin-1 receptor antagonists, may represent a new type of anti-HIV therapy, due...

Leading lampreys to slaughter: Pheromone for scourge of Great Lakes identified

...e of PADS is very similar to that of squalamine, a compound made by the "dogfish" shark. Squalamine has been reported to work against cancer by inhibiting the growth of blood vessels that feed tumors but not other blood vessels. The other two components of the pheromone are a second steroid and an already kno...

Jefferson scientists identify gene defect leading to abnormal skin development and cancer

...e of PADS is very similar to that of squalamine, a compound made by the "dogfish" shark. Squalamine has been reported to work against cancer by inhibiting the growth of blood vessels that feed tumors but not other blood vessels. The other two components of the pheromone are a second steroid and an already kno...

Switching to new anti-bacterial targets: Riboswitches

...disrupted in the presence of pyrithiamine, a toxic compound related to the vitamin. Bacteria and fungi fail to grow in pyrithiamine and become resistant by acquiring mutations in their riboswitches. This work, in combination with the recently solved crystal structures of purine riboswitches, opens a path to ...

Sea slug mixes chemical defense before firing at predators

...for its potential applications as an antimicrobial compound for the healthcare and marine industries. The team has determined that escapin prevents the growth of all major forms of bacteria as well as other microbes. "As we learn more about how escapin works in Aplysia, we will hopefully be able to reproduce...

UK sperm donor crisis

...s, which is not appropriate, as this will not only compound the problem but also disappoint patients. Testing two samples may increase acceptability rates, but a man who has variable samples may not always produce samples suitable for freezing. This will increase the number of ejaculates he needs to donate an...

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