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Tag: "compound" at biology news

Promiscuous Catalytic Activity Possessed by Novel Enzyme Structure

...le, all the chemistry associated with the original compound changes,?said Noel. He explained that the addition of a prenyl group, also known as prenylation, produces a relatively large change in the chemical’s biological properties. “The molecule becomes a little bit more greasy, and so the kinds of targets t...

Stem cell training program to make its Stanford debut

...le, all the chemistry associated with the original compound changes,?said Noel. He explained that the addition of a prenyl group, also known as prenylation, produces a relatively large change in the chemical’s biological properties. “The molecule becomes a little bit more greasy, and so the kinds of targets t...

Compound from Chinese medicine shows promise in head and neck cancer

A compound derived from cottonseed could help improve the eff...ehensive Cancer Center, discovered (-)-gossypol, a compound derived from a component of Chinese medicine. Gossypol comes from cottonseed and was once used in C...

Slipping past the blood brain barrier: Research shows potential treatment for brain cancer

A compound that kills cancer can sneak past the blood brain b...f Medicine and a member of the research team. The compound - JV-1-36 - is an antagonist of the hypothalamic growth hormone- releasing hormone, which has been f...

Structures of marine toxins provide insight into their effectiveness as cancer drugs

...er drug, it is a good idea to know how the natural compound works," he says. "Scientists who study natural products take their cues from what nature has already done. We're adding deep biochemical meaning to this area." He adds that synthetic chemists hope that actin-based drugs might one day rival the suc...

Seaweed could make junk food healthier

...y to produce the extract, alginate, a carbohydrate compound which is a tasteless and odourless off-white colou...r and it's unlikely to taste any different. "This compound can also be added to any number of foods, such as synthetic creams and yoghurts. With pork pies, on...

Discovery of T-cell 'traffic control' boosts new drug promise

...e traffic control system -- composed of a fat-like compound called S1P and its receptor on T cells -- usually prevents T cells from launching harmful reactions. But when the S1P traffic cop reacts incorrectly, T cells can swamp healthy tissue. The new research explains how a promising experimental drug treats...

Molecular miners find pain relief drugs from the sea

...rofessor Khalil. ACV1 is not the only therapeutic compound that cone snail venom has to offer. In fact, the venom is a cocktail of thousands of biologically active compounds of which only a few hundred have been identified. Associate Professor Gayler says the team, by using genes as the starting point, are ...

UIC developing drug for SARS

...to be 1,000 times more effective than the original compound in inhibiting 3CLpro. However, Johnson, said, the...in the proteases to put them out of business." "A compound that blocks all these sites, rather than just a few, and that conforms tightly to the pockets, is ul...

Clear rules needed to govern deep sea bioprospecting: UNU

...ucts: US$ 100 billion; * Annual profits from a compound derived from a sea sponge to treat herpes: US$ 50 ...vatives of a sponge while a sponge-derived steroid compound completed phase one US trials as an asthma drug in 2000. Other research in progress includes treatme...

A Father’s Day Gift: Free DNA Paternity Testing

...ucts: US$ 100 billion; * Annual profits from a compound derived from a sea sponge to treat herpes: US$ 50 ...vatives of a sponge while a sponge-derived steroid compound completed phase one US trials as an asthma drug in 2000. Other research in progress includes treatme...

Ants, not evil spirits, create devil's gardens in the Amazon rainforest, study finds

... notes. Chemical analysis revealed that the only compound produced by the ants' poison glands is formic acid, a toxin that is common in many ant species and, in fact, got its name from formica, which is Latin for ant. "Treatment of leaves with formic acid induced leaf necrosis on all the plants we tested," ...

Protein structure key for AIDS, cell function

...rnell researchers identified a peptide, an organic compound composed of amino acids, that they believe may play a role in interrupting the interface between CD4 and HIV-AIDS. The findings, published in the journal Structure (Vol. 13, Sept. 2005), mark a major step toward designing drugs that could inhibit p...

Environmental lessons from tsunami as world's coastal population doubles

...coastal cities ?many these being Asian cities. To compound this, many weather-related disasters are becoming more destructive and intense due to climate change. The report is based on two case studies ?the Asian tsunami in 2004 and the impact of severe storms in the Caribbean over the past twenty years. Th...

Drugs from the deep blue

... to start from conventional chemistry and make the compound in the lab, then try to find the simplest structur...s five percent of the animal may be made up of one compound -- a big investment of energy and resources. Chemical ecology is the field of research that explore...

Tiny avalanche photodiodes target bioterrorism agents

...devices, based on aluminum gallium nitride (AlGaN) compound semiconductors, have a photocurrent gain of more t...of solar-blind APDs is based on wide bandgap AlGaN compound semiconductors. To date, no semiconductor-based solar-blind APDs have been reported. This is due to ...

Vaginal gel may provide a new approach to HIV prevention

...ny pharmaceutical company has licensed an anti-HIV compound for development as a microbicide when the class of drugs is so early in development. Women make up nearly half of all people living with HIV worldwide, and 80 percent of new cases of HIV infection in women result from heterosexual intercourse. A vag...

Dendritic cells offer new therapeutic target for drugs to treat MS and other autoimmune disease

...colleague Katherine Whartenby used an experimental compound called CEP-701, already known to block actions of the growth-promoting FLT3 gene, on human dendritic cells and in mice engineered to mimic multiple sclerosis, a disease that causes T-cells to destroy the myelin protein sheath around nerves in the cen...

UT Southwestern researchers develop screening test for cells that activate immune system

...to. Previously, scientists would have to test each compound individually, a time-consuming process. Their research already has led to the discovery of several compounds that turn on dendritic cells, which are found throughout the body from skin to blood. They continuously scan the body at the cellular level ...

Biotechnology's newest chemical tool

...up to its target compound. But delivering a larger compound required an auxiliary "spring" to ensure it would reach the target. So, he said, "chemical thinking" helped resolve the problematic enzymatic reaction. "By demonstrating the transfer of carbon chains as long as 4 to 5 units, we provide proof of pri...

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