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Tag: "compound" at biology news

Man-made wetland's effectiveness similar to natural marsh

...n't quite the same with nitrates ?a nitrogen-based compound found in fertilizer. "As a wetland gets older, it gets better at handling and storing nitrogen," Mitsch said. "The idea is not to overload wetlands in the first place." The three-acre wetland in the study was roughly the size of three football fiel...

Molecular thermometers on skin cells detect heat and camphor

...ured keratinocyte cells, TRPV3 is activated by the compound camphor, which is one of the main ingredients in many warming rubs. TRPV3 is the first known receptor for camphor. Significantly, when Patapoutian and his colleagues discovered TRPV3 a few years ago, they were intrigued to discover that it is unique...

Future diabetes drugs may target new protein interaction

...however. In 2003, other scientists reported that a compound found in red wine activated yeast's sirtuin1-equivalent and extended the organism's lifespan. Moving up the food chain, decades of reports have shown that drinking moderate amounts of red wine is associated with a longer life for people. But at this...

PHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information

...however. In 2003, other scientists reported that a compound found in red wine activated yeast's sirtuin1-equivalent and extended the organism's lifespan. Moving up the food chain, decades of reports have shown that drinking moderate amounts of red wine is associated with a longer life for people. But at this...

Computational verification of protein-protein interactions by orthologous co-expression

...however. In 2003, other scientists reported that a compound found in red wine activated yeast's sirtuin1-equivalent and extended the organism's lifespan. Moving up the food chain, decades of reports have shown that drinking moderate amounts of red wine is associated with a longer life for people. But at this...

Eliminate Data Analysis Bottlenecks in Drug Discovery

...however. In 2003, other scientists reported that a compound found in red wine activated yeast's sirtuin1-equivalent and extended the organism's lifespan. Moving up the food chain, decades of reports have shown that drinking moderate amounts of red wine is associated with a longer life for people. But at this...

At the molecular level, the predator is the prey

...some T. sirtalis garter snakes. TTX is a defensive compound found in some puffer fish, octopuses and primitive chordates. It is used in low concentrations to treat morphine and heroine addicts. It's also the "zombie" drug used by Haitian voodoo ritualists. Despite its action at the molecular level, the evolu...

While on trail of dioxin, scientists pinpoint cancer target of green tea

... protective effects, and that could help us find a compound that is much more potent." Palermo, Gasiewicz, and current undergraduate Claire Westlake discovered that a chaperone protein known as HSP90 is involved in conferring green tea's protective effects. Other researchers have shown that many cancer cells...

Innovative coating could give medical implants a longer life

...to the body's enzymes. In contrast, the molecular compound developed at Northwestern, which sticks securely to a surface and prevents cell and protein buildup, works for a long period of time. In laboratory studies, the new coating provided effective fouling resistance for more than five months, which Philli...

Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines

...lgorithm that predicts the precise effects a given compound will have on a cell’s molecular components or chemical processes. Using this tool, drug developers can design compounds that will act on only desired gene and protein targets, eliciting therapeutic responses free of unwanted side effects. The resear...

Protein synthesis can be controlled by light, opening way for new scientific, medical applications

...tivates the bioactive molecule. Exposing the caged compound to light releases the effector in its active form.... molecule." The team developed a caged anisomycin compound that can be activated by exposure to ultraviolet light or an infrared laser beam. (Anisomycin is an ...

Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT

...ew Jersey is acquiring the licensing rights to the compound from USF through its merger with Greenwich Therapeutics Inc. and is planning clinical trials with Moffitt. The trials are expected to start within six to eight months. Patients will be selected for the trials based on whether their tumors have hypera...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...ny-stimulating factor (G-CSF) to create a new oral compound that is capable of surviving the journey through the gastrointestinal (GI) tract and then able to cross over into the bloodstream to be used by the body, according to research from the University of Southern California School of Pharmacy. This techn...

Scientists discover the body's marijuana-like compounds are crucial for stress-induced pain relief

... of the body's naturally occurring cannabinoids, a compound known as 2-AG, has anything to do with pain regula...rsity of California-Irvine, is the discoverer of a compound that blocks the breakdown of this marijuana-like compound called 2-AG, and it is that blocking compo...

Newly discovered genetic disease sheds light on body's water balance

...MD, Gitelman administered urea, a natural nitrogen compound that encourages urination by acting as an osmotic agent. As water flowed out of their bodies and sodium concentrations returned to normal, both babies recovered. They continue to be followed by the UCSF team. Next Gitelman, Rosenthal and Feldman too...

Environmental chemical cocktail may sabotage sperm

...ans are likely to be exposed to more than one such compound at any given time and, secondly, our results show that human sperm are even more sensitive to these compounds than mouse sperm." Prof Fraser and her team tested combinations of three chemicals: genistein, 8-prenylnaringenin which is found in hops, a...

Novel compounds show promise as safer, more potent insecticides

...ch scientist at Nihon Nohyaku. In early tests, the compound showed high activity against the tobacco budworm (... tobacco and other crops, the researchers say. The compound did not have any measurable effect on mammalian ryanodine receptors, according to Peter Lümmen, Ph.D...

Anthrax inhibitors identified by Burnham team

... working on refining the chemical structure of the compound with the goal of achieving an even more potent and selective drug that should exhibit a higher degree of protection against anthrax." This research was supported by grants from the National Institute of Allergy and Infectious Diseases, from the Nati...

Gifts from the sea

...oe crab (Limulus polyphemus): The horseshoe crab's compound eye and the (easily accessible) optic nerve that connects the eye to the brain are both relatively large, making this organism a great model for the study of vision. MBL scientists have also made significant research breakthroughs related to the hor...

Compound might defeat African sleeping sickness, clinical trial beginning this month

... terrible re-emerging disease," Tidwell said. "The compound DB289 will be the first new drug for early stage (blood stage) African sleeping sickness in 50 years, and the only oral drug that's ever been specifically developed for it." Oral administration is important for treating the disease which occurs in v...

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