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Tag: "components" at biology news

A new mechanism of regulating RNA degradation

...scovered that Staufen1 doesn't interact with other components of the NMD complex ?and altering the amount of Staufen1 in the cell didn't change NMD function. Those observations, said Maquat, sent Kim on a hunt for what Staufen1 and Upf1 were doing. Looking at gene expression data available through the lab of L...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...scovered that Staufen1 doesn't interact with other components of the NMD complex ?and altering the amount of Staufen1 in the cell didn't change NMD function. Those observations, said Maquat, sent Kim on a hunt for what Staufen1 and Upf1 were doing. Looking at gene expression data available through the lab of L...

W.M. Keck Foundation funds study of friendly microbes

...lories to be harvested from otherwise indigestible components of the diet, such as polysaccharides. These microbes also regulate the amount of extracted energy that is stored in fat cells. The implication of these findings is that variations in the composition of gut microbial communities among different people...

Fox Chase Cancer Center scientists identify immune-system mutation

...ocess." Understanding the development of critical components of the immune system can contribute to medical advances in stimulating desirable immune responses and halting undesirable immune reactions, Kappes said. This understanding can further progress against various immune disorders, allergies and certain c...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...cans is occurring between cells," said Gage."Also, components of the growth medium have the capacity to change theimmunological characteristics of the human ES cells. More research isneeded to understand the optimal conditions for preparing human cellsfor therapeutic application.""We considered that one partial...

Genome-wide mouse study yields link to human leukemia

...nding T cells and natural killer cells, both major components of the immune system. In comparing the mice in the pre-leukemic stage and those with ALL with normal mice, researchers found that methylation, a chemical process that adds methyl molecules to DNA, silenced a number of genes ?but only in the mice wit...

Clam embryo study shows pollutant mixture adversely affects nerve cell development

...s the first time anyone hasdemonstrated that BCE's components can work together to adverselyaffect neuron growth...Of the different combinations and strengths of BCE components tested,we found that all three together induce the greatest adverse response.Treating the embryos wi...

Study identifies predictors of HIV drug resistance in patients beginning triple therapy

...s the first time anyone hasdemonstrated that BCE's components can work together to adverselyaffect neuron growth...Of the different combinations and strengths of BCE components tested,we found that all three together induce the greatest adverse response.Treating the embryos wi...

In the sea slug's defense against lobsters, confusion is key

...ickery that had not previously been appreciated as components of chemical defense. When attacked by predatory spiny lobsters, sea slugs (also known as sea hares) release an inky secretion, termed ink and opaline, from a pair of glands. The new findings show that Aplysia's defensive secretion includes a variety...

Researchers identify target for cancer drugs

...ave identified elements of this pathway, other key components have remained a mystery. Researchers at Whitehead Institute now have discovered a missing puzzle piece, a finding that may present drug makers with a significant new cancer target. "We believe that we have identified a component that researchers hav...

Plant hemoglobins: Oxygen handlers critical for nitrogen fixation

Hemoglobins, key components of our blood, are ancient proteins with well-known roles in oxygen transport and respiration in animals. Hemoglobins are also present in plants and bacteria, but until now the physiological role of plant hemoglobins has been unclear. A group of resea...

Scientists rid stem cell culture of key animal cells

...should improve safety. However, not all the animal components have been removed from the media yet, but this is an important step." Working with three of WiCell's five human embryonic stem cell lines, Xu and his team explored the molecular interactions within the stem cell growth medium. He discovered that, in...

Critical role in programmed cell death identified

...apparatus. Mammals on the other hand have multiple components or families of proteins for these factors; moreover, their cell death is more sporadic and harder to pinpoint. In worms, scientists know exactly which cells are dying, and when and where. During development, 1,090 cells form, but 131 of these cells ...

Researchers discover molecule that causes secondary stroke

...vivors are at greater risk." Several spinal fluid components were suspected of causing the vasospasm, Dr. Clark explains. They included hemoglobin, bilirubin and peroxidized lipids, and a group of bilirubin oxidation products that the researchers called BOXes. Building on Dr. Clark's earlier studies in rats, ...

Highly adaptable genome in gut bacterium key to intestinal health

...heta to change the activity of genes that code for components of its outer surface cell capsule. This change in the face of this friendly, or symbiotic, species may be an important mechanism to avoid causing a potentially damaging or disruptive host immune response. "B. theta is an incredibly sophisticated and...

Development of portable infectious disease detector

...spects of the design was to keep thefluid-handling components separate from the microelectronics. Theresulting device is considerably larger than comparable lab-on-a-chipsystems but it is also much less expensive. "That's one of theappealing features about Pria's approach," says Wikswo, "They keeptheir microflu...

NC State scientist finds soft tissue in T. rex bones

...erested in studying the microstructure and organic components of a dinosaur's bone. All bone is made up of a combination of protein (and other organic molecules) and minerals. In modern bone, removing the minerals leaves supple, soft organic materials that are much easier to work with in a lab. In contrast, fos...

Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease

...in a soup in equilibrium," he said. Given that the components of amyloid fibrils measure only billionths of a meter and are floating in a disordered mix, "the initial stages of amyloid aggregation are not fully understood," he said. "When you start a normal reaction, molecules are free in solution so they inte...

Tiny scaffolding allows stem cells to become working fat cells

...e. They failed to produce the genetic and biologic components that all cells require to do their work. This discovery offers hope of a new approach to growing fat tissue for use in breast reconstruction surgery and other clinical needs, and may even be important for curing type II diabetes. Douglas Kniss, pro...

Scientists identify new model Of NK cell development

...iller (NK) cells, powerful but somewhat mysterious components of the body's immune system that are the first line of defense against cancer and infectious diseases. Scientists have believed for years that human NK cells are generated in bone marrow, but Michael Caligiuri, director of the OSU Comprehensive Canc...

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