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Tag: "complex" at biology news

DNA Molecules Used To Assemble Nanoparticles

... flock to the diseased cells. The other end of the complex carries a fluorescent protein so that the research...molecule would self-assemble into a four-dendrimer complex carrying one drug, one target, and one fluorescent. ...

Wisconsin scientists grow critical nerve cells

...al to expose the growing stem cells to an array of complex chemical cocktails. The cocktails constitute natur...as scientists always believed. Rather, a series of complex overlapping changes may well be the developmental norm in higher vertebrates such as humans. "We ca...

A new mechanism of regulating RNA degradation

... from transcription could be regulated by the RISC complex (siRNA-mediated degradation via Dicer). And now it...eems that regulation at the RNA level is even more complex than we first imaginated... As any dedicated video game player knows, the first requirement for us...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

... from transcription could be regulated by the RISC complex (siRNA-mediated degradation via Dicer). And now it...eems that regulation at the RNA level is even more complex than we first imaginated... As any dedicated video game player knows, the first requirement for us...

UAB scientists discover the origin of a mysterious physical force

... a remarkable capacity to organise themselves into complex structures that are strongly orientated in such a way as to cancel out the electric field, and on some occasions, to reverse it. This abnormal behaviour was discovered by the same researchers and published in Physical Review Letters in April 2004. T...

Novel technology detects human DNA mutations

...ysis of whole human genomic DNA is extraordinarily complex asit requires sifting through the more than one billion base pairs of DNA to find a particular base pair of interest. Once that base pair is located, it is then necessary to determine if either of the bases is mutated (i.e., has SNPs). Nanosphere's t...

Priming embryonic stem cells to fulfill their promise

...in the body.Embryonic stem cell differentiation is complex and far from fullyunderstood. Scientists are focusing on four types of external inputsknown to be involved in triggering the differentiation of stem cells:soluble growth factors, adjacent cells, mechanical forces, andextracellular matrix proteins tha...

Growth in the sea comes down to a struggle for iron

...rget iron with these molecules. Siderophores don't complex other metals very well. The idea is that it (the molecule) is like a magic bullet. They release it, it binds iron, and then only they have the key to unlock it and get the iron out of it. "Now in reality it's warfare. In some cases other bacteria hav...

New, automated tool successfully classifies and relates proteins in unprecedented way

...ation in a cellimage. SLFs measure both simple and complex aspects of proteins, suchas shape, texture, edge q...ntology terms were too limited todescribe the many complex location patterns we found. Of course, theother drawback of term-based approaches is that they have ...

New binding target for oncogenic viral protein

..., Fbw7. This protein is part of a ubiquitin ligase complex that adds ubiquitin to proteins to mark them for destruction by the cell. Fbw7 recognizes a destruction signal on certain proteins that need to be degraded and brings them in close proximity to the enzymes that attach ubiquitin. The proteins recogniz...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

..., keeping everything in balance. But diabetes is a complex metabolic disorder with numerous players such as high levels of blood glucose, cholesterol and other lipids. "The challenge is to figure out which factors are a primary cause of diabetes and which are a consequence, said Dr. Patti. "In our study, we ...

Fox Chase Cancer Center scientists identify immune-system mutation

...ither class I or class II major histocompatibility complex (MHC) molecules. Most helper T cells carry a surface protein called CD4, which is attracted to class II MHC. Killer cells carry the CD8 protein, attracted to class I MHC. However, the underlying molecular pathways that regulate this process have rema...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

... in developing countries, includes an unexpectedly complex repertoire of sensory genes as well as a variety o...nsion of some gene families characteristic of more complex organisms. Detailing the first systematic study of relatively recent horizontal gene transfer into ...

Anti-bacterial additive widespread in U.S. waterways

...al and humanhealth risks? This is a scientifically complex question consumers,knowingly or unknowingly, answer to everyday in the checkout line ofthe grocery store," said Dr. Halden....

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...ion. The ability of a single biochemical factor or complex of factors to have this dual role may represent a ...od Pan and Peter Pan, who were able to orchestrate complex events while never growing old." Epstein thinks that this concept may also be important for underst...

Timing is everything: First step in protein building revealed

...om getting started. Only afterits release from the complex can the ribosome start making proteins."No one had any idea when eIF1 was released from the ribosome, or thatits release might serve an important purpose, so this was a completelyunexpected result," says graduate student David Maag, first author ofth...

Plants, animals share molecular growth mechanisms

A newly discovered plant protein complex that apparently switches on plants' growth machine...cording Purdue University scientists. The protein complex triggers communication between molecules along a pathway that leads to the creation of long protein ...

Research advances quest for HIV-1 vaccine

...es AIDS. A new detailed structural analysis of the complex formed by an anti-HIV antibody called 4E10 and its... examining the detailed molecular structure of the complex formed when 4E10 binds to gp41 and determining how interaction of 4E10 with gp41 influences the viru...

Computers to be used to find blueprint for new influenza drug

...ware to model the way these atoms behave in highly complex interactions, the atomic structure of a suitable drug can be worked out. Using computer modelling in this way can be of great assistance in drug design. Normally drugs are produced by trial and error in a process that can take many years. Professor...

Ecological destruction fuels emerging diseases

...ll require a detailed understanding of their often complex multi-host life cycles. "It's very difficult to link these things up," he says. "It's very time consuming to do that, but without that information we don't know how these parasites are transmitted." And without basic systematics and taxonomic infor...

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