Junk DNA may not be so junky after all
...ies have changed over time, traditional methods of comparing DNA sequences between humans and zebrafish have failed to identify any potential enhancers around the RET gene because the DNA sequences differ too much. That drove the Hopkins researchers to seek and develop this new system, by which virtually any ...... similar molecular instructions. Furthermore, when comparing the initial development of the structures, the researchers realized that the teeth forming in the chicken did not look like mammalian teeth, but resembled those of the alligator, the closest living relative of modern birds. The findings strongly su...Sexual reproduction delays aging in a mammalian species
...t the year, the helpers are sexually quiescent. By comparing the long-term survival of breeders and non-breeders, Dammann and Burda found that the former lived extraordinarily long (up to 20 years) and on average about twice as long as their non-breeding counterparts. The researchers were also able to show tha...Powerful new tool for studying brain development
...mples of human brain tumors called ependymomas. By comparing the gene expression patterns in human ependymomas with those in the normal developing mouse nervous system provided by the BGEM, the St. Jude investigators demonstrated that specific brain cells, called radial glial cells, likely gave rise to ependym...Largest study of human 'interactome' reveals a novel way
...rticle. The team's conceptual advance was made by comparing human data with 6,014 genes in yeast and 2,284 genes in mice whose effect on survival was known, according to Pandey. "Our much larger database on genes and proteins gave us the information to set the record straight on how to measure a protein's im...'Virus chip' detects new virus in prostate tumors
...rochip is designed to identify any virus sample by comparing its DNA or RNA to more than 20,000 snippets of genetic material derived from all known viruses -- found in humans, animals, plants, fungi and bacteria. The chip draws on computer chip technology, computation and bioinformatics, but in essence it is a...Infant transplant patients resist infections that kill adult AIDS patients
...ncer." The Mayo Clinic researchers report results comparing T cell function between transplant patients 1-10 years post transplant and healthy people matched to the transplant patients by age and gender. To compare T cell function, they measured the T cell response to select viral immunization. This compariso...Scientists develop protein-sequence analysis tool
... the related but functionally different class. But comparing sequences "manually" is labor intensive, error prone, and has become impractical for those who wish to take advantage of the increasing number of sequences in protein databases, Shanklin said. "Yet this growing data resource contains a wealth of inf...Poison + water = hydrogen. New microbial genome shows how
...nt to heat, radiation, and other treatments. By comparing this genome to those of other spore-making species, including the anthrax pathogen, Eisen and colleagues identified what may be the minimal biochemical machinery necessary for any microbe to sporulate. Thus studies of this poison eating microbe may ...Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool
...last bit is set to 1; otherwise it is set to 0. By comparing the number of 1's on the sending end with the value of the last bit on the receiving end, the recipient's computer can determine whether the message was accurately received. If not, the recipient's computer asks the sender's computer to forward the m...Technique offers new view of dynamic biological landscape
...own" the activity of a multitude of gene pairs and comparing the effects of those changes to those that result when each gene is dialed down individually. Many genes' activity could be reduced by eliminating them entirely, but for the subset of genes that are essential for yeast growth -- whose complete deleti...Ancient humans brought bottle gourds to the Americas from Asia
...heir modern counterparts in Asia and Africa before comparing the plants' genetic make-up to determine the origins of the New World gourds. "For 150 years, the dominant theory has been that bottle gourds, which are quite buoyant and have no known wild progenitors in the Americas, floated across the Atlantic O......omputing, says that Blackwatch "casts a wide net", comparing orders against sequences from organisms identified by the US government as "select agents" that raise bioterror concerns. But not all of these sequences are dangerous, and some customers may have the clearance to work with those that are. So even leg...Discovering the first steps in transcription-coupled repair
...R was discovered about 20 years ago as a result of comparing the properties of cells from patients with Cockayne Syndrome (CS) versus those with xeroderma pigmentosum (XP), two different hereditary diseases with a common feature: both entail extreme sensitivity to sunlight. However, in XP there is loss of abil...Carnegie Mellon scientists create PNA molecule with potential to build nanodevices
...h done on the same type of DNA microarray and each comparing brain regions in young versus old adult humans. In four different regions of the cortex (the brain region responsible for higher functions such as thinking), they found a similar pattern of age-related change, characterized by changes in expression o...Navigating the brain for sense of direction as paradigm for higher cognitive functions
...h done on the same type of DNA microarray and each comparing brain regions in young versus old adult humans. In four different regions of the cortex (the brain region responsible for higher functions such as thinking), they found a similar pattern of age-related change, characterized by changes in expression o...Gene Expression in the Aging Brain
...h done on the same type of DNA microarray and each comparing brain regions in young versus old adult humans. In four different regions of the cortex (the brain region responsible for higher functions such as thinking), they found a similar pattern of age-related change, characterized by changes in expression o...Same-sex mating by fungi spawned infection outbreak, evidence suggests
... strain, which made up the other five percent. By comparing select gene sequences that spanned the genomes of the Vancouver Island fungi to samples collected from around the world, the team traced the rarer type to identical isolates in Australia. The major form matched a sample taken from an infected person ...New study examines how sense of smell affects mating and aggression in mice
...arate times in cages with the male mutants. When comparing the mutant males with wild-type males, study results showed that all wild-type males mated with test females, while none of the mutants engaged in sexual behavior with the females. "Typically, when you take a female and put her in a cage, the male wi......ce--it is well-defined and lasts only 24 hours. By comparing the changes in gene activity caused by endotoxin exposure with those caused by trauma, the researchers hope to identify the molecular markers that spell sepsis. The research team zeroed in on white blood cells, which help fight infection and diseas...