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Tag: "comparative" at biology news

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...research involving the structural, functional, and comparative analysis of genomes and gene products in viruses, bacteria, archaea, and eukaryotes. ...

Breakthrough Microarray-based Technology for the Study of Cancer

... severalscientific hurdles that previously impeded comparative genomic studiesin cancer. Chromosomal changes inc... among the cancer research community."In the past, comparative genomic hybridization was performed throughthe optical imaging of whole chromosomes, a technique wit...

Study finds more than one-third of human genome regulated by RNA

..."This study is an excellent exampleof the power of comparative genomics to illuminate how human genes areregulated," says Burge."As more genome data becomes available and the technology becomes moresophisticated, I think we'll find that even more genes are targeted bymicroRNAs," predicts Lewis.In addition, the t...

NYU researchers simulate molecular biological clock

..."This study is an excellent exampleof the power of comparative genomics to illuminate how human genes areregulated," says Burge."As more genome data becomes available and the technology becomes moresophisticated, I think we'll find that even more genes are targeted bymicroRNAs," predicts Lewis.In addition, the t...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

...The research team completed a rigorous statistical comparative analysis of a total of 14,145 yeast (Saccharomyces cerevisiae), worm (Caenorhabditis elegans), and fly (Drosophila melanogaster) proteins with 38,965 known interactions. Their PathBLAST tool generated a list of similar proteins in the three species t...

Sequencing of marine bacterium will help study of cell communication

...lobal regulatory networks through a combination of comparative genomics and experimental molecular biology. Othe...g bacteria–host interactions, we must begin to use comparative genomic approaches with closely related pathogenic and beneficial microbial species." Marie Faini O...

Antibiotic might fight HIV-induced neurological problems

..." says Christine Zink, D.V.M., Ph.D., professor of comparative medicine at the Johns Hopkins University School of... says Sheila Barber, Ph.D., assistant professor of comparative medicine. "Testing minocycline in our animal model of HIV infection was really a logical next step."...

Multiple Campylobacter Genomes Sequenced

... Derrick Fouts and his colleagues have taken this comparative approach with Campylobacter. Infection with a Camp...ences to functional differences, but this detailed comparative genomic analysis provides the core blueprint for this important family of human pathogens. And in do...

Researchers uncover sequence of major rice pathogen

...o this, he and his colleagues used two strategies: comparative genomics and functional genomics. "In comparative genomics, you compare this genome to that of other organisms, other fungi," Dean says. "But fungi ar...

Scientists journey to southern Africa to unravel the secret world of elephant communication

...terinarian Donna Bouley, an associate professor of comparative medicine at Stanford, and undergraduate Christina Alarcon are dissecting the foot of an Asian elephant that recently died at a zoo. Preliminary results reveal a high density of Pacinian corpuscles in the front of the foot and along the edges--a findi...

Agilent Technologies new genome analysis technology set to accelerate Australia fight against mesothelioma

... advanced. Agilent's new microarray techniques in comparative genomic hybridization (CGH) will allow researchers to rapidly and reliably identify genetic changes in tumorous cells. It is believed that specific genetic changes may accompany the onset and progression of the disease. Dr. Andrew Holloway of the Pe...

NHGRI targets 12 more organisms for genome sequencing

... be sequenced at less dense coverage to aid in the comparative studies. Sequencing efforts will be carried out by the five centers in the NHGRI-supported Large-Scale Sequencing Research Network: Agencourt Bioscience Corp., Beverly, Mass.; Baylor College of Medicine, Houston; the Broad Institute of MIT and Harva...

Scientists identify genes responsible for 'black rot' disease in vegetables

...rldwide. Their study, which represents the largest comparative and functional genomics screen for a plant or anim...t for "black rot" disease. Employing whole-genome comparative genomic approaches, the authors sequenced the complete genome of an Xcc strain that was isolated fro...

DOE JGI launches IMG public online microbial genome data clearinghouse

...rm that supports timely analysis of genomes from a comparative functional and evolutionary perspective." "IMG's ...increases with the number of genomes available for comparative analysis." Nikos Kyrpides, of DOE JGI's Microbial Genome Analysis Program (MGAP), provided scientif...

Bioinformatics reveals new gene regulation system

...and his postdoctoral fellow, Dmitry Rodionov, used comparative genomics to identify a new transcription factor sy...of of principle that you can go a very long way by comparative genomics now." Their findings will be published in the July issue of Trends in Genetics, with early ...

'Punctuated' evolution in the human genome

...tic predecessors. The scientists then performed a comparative analysis of these duplicons in other primate species, including chimpanzee, gorilla, orangutan, baboon, and macaque. This analysis revealed that the duplicative transposition events leading to the establishment of these duplicons within the pericentr...

Looks matter to female barn swallows

... Then she let the pairs breed again. She conducted comparative DNA tests on the offspring from the first and second nests. In the research, all 30 females remained socially paired with their original male mate, but they were sexually active with other males. The males with enhanced color fathered a substantiall...

Researchers predict infinite genomes

...tling conclusion. Armed with the powerful tools of comparative genomics and mathematics, TIGR scientists have con...l do these microbial genomes reflect reality? As comparative genomics itself evolves, Fraser expects TIGR to increasingly focus on pan-genomes. Many questions re...

NHGRI Selects 13 More Organisms for Genome Sequencing

...nome is important because its sequence will aid in comparative annotation of the genomes of other roundworms that... To learn more about the rapidly growing field of comparative genomic analysis, go to: www.genome.gov/11509542. For the white papers on other organisms currently ...

Possible treatment found for 'chemobrain'

...nome is important because its sequence will aid in comparative annotation of the genomes of other roundworms that... To learn more about the rapidly growing field of comparative genomic analysis, go to: www.genome.gov/11509542. For the white papers on other organisms currently ...

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