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Spleen may be source of versatile stem cells

..."This data also shows the kind of payback that can come fromstudies of lower animals like newts and sponges. Combining theknowledge of Hox11's role in those animals with what we'd found aboutislet cell regeneration in mice helped us find this previously unknownexample of normal, controlled Hox11 expressio...

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...depth in oceanic crust. The fluids that emerge may come in bursts when earthquakes occur; fluid flow may therefore repeat episodically over hundreds of thousands of years as abyssal hills are uplifted and spread away from the mid-ocean ridge crest. Haymon compared the subsurface microbes they found to th...

W.M. Keck Foundation funds study of friendly microbes

...entally test predictions about gene functions that come from our computer-assisted analyses." Gordon views the human gut as "a bioreactor programmed with at least 800 different species of bacteria." "Fortunately, these microbes endow us with key metabolic functions that we have not had to evolve on our o...

Growth in the sea comes down to a struggle for iron

...eanographer Mark Wells. And diatoms may not always come out on top. In collaboration with a large Japanese research program, Wells and a team of scientists from UMaine and other universities are studying the fate of iron in marine waters. Their findings could help determine the fate of something else, a ...

Timing is everything: First step in protein building revealed

...some complexitself assembles and how other factors come and go as it translatesgenetic information to buil...chers examined how fast the pieces of the ribosome come together,and how long it takes them to fall apart under various circumstances.Their results support ...

Tiny particles could solve billion-dollar problem

...ble to maximize the number of palladium atoms that come in contact with TCE molecules and improve efficiency by several orders of magnitude over bulk palladium catalysts." TCE, which is commonly used as a solvent to degrease metals and electronic parts, is one of the most common and poisonous organic pol...

Research advances quest for HIV-1 vaccine

...hen scientists from multidisciplinary laboratories come together to tackle a major scientific challenge. " ### Rosa M.F. Cardoso, Michael B. Zwick, Robyn L. Stanfield, Renate Kunert, James M. Binley, Hermann Katinger, Dennis R. Burton, and Ian A. Wilson: "Broadly Neutralizing Anti-HIV Antibody 4E10 Reco...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...representing experimental “noise.?Such results may come about from such procedural problems as incomplete randomization of samples, Baggerly says. The study raises a question that is broader than the effectiveness of the experimental ovarian cancer test, the researchers say. “Are we going to be able to m...

New species from old data

...representing experimental “noise.?Such results may come about from such procedural problems as incomplete randomization of samples, Baggerly says. The study raises a question that is broader than the effectiveness of the experimental ovarian cancer test, the researchers say. “Are we going to be able to m...

Cracking the olfactory code in bees

...representing experimental “noise.?Such results may come about from such procedural problems as incomplete randomization of samples, Baggerly says. The study raises a question that is broader than the effectiveness of the experimental ovarian cancer test, the researchers say. “Are we going to be able to m...

Signaling protein builds bigger, better bones in mice

...representing experimental “noise.?Such results may come about from such procedural problems as incomplete randomization of samples, Baggerly says. The study raises a question that is broader than the effectiveness of the experimental ovarian cancer test, the researchers say. “Are we going to be able to m...

A much-needed shot in the arm for HIV vaccine development

...my contention thatgreat new ideas are as likely to come from curiosity-driven basicstudies as from the mission-oriented approach that is represented bythe new proposal."The PLoS Medicine editors hail the plan as being a "crucially importantoutline for vaccine development." But in their editorial, they als...

Ancient olfaction protein is shared by many bugs, offering new pest control target

...sect pests, new research indicates that it may all come down to the sense of smell. A group of Rockefeller University scientists who had previously identified a key gene essential for the sense of smell in fruit flies now shows that this gene's function appears to be evolutionarily conserved across very d...

New Technique for Tracking Gene Regulators

...he size of genome they can analyze.Dunn’s team has come up with a technique to determine the positions ofthese 500-to-1,500-base-long pieces on an entire genome ?even one aslarge as the human genome ?relatively quickly and in very largenumbers.After isolating the CREB-bound fragments, they release the CRE...

Learning to fight an adversary that won't stay down

...a relatively small number of antibiotics that have come out that are new, and some of them are very potent and act against most resistant strains," he says. "But the clinicians rightly try to keep these things in reserve for when they are really needed." ...

Scientists rid stem cell culture of key animal cells

... today (Feb. 17) in the journal Nature Methods and come on the heels of a recent University of California study showing that existing stem cell lines are already contaminated with an animal molecule. The potential threat of animal pathogens tainting human stem cell lines poses a problem for the safe clini...

Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra

...es, he said. "Wherever the puffins and gulls have come back after the removal of the foxes, the vegetation has started to become lusher again," Byrd said. "The terrestrial ecosystem was probably modified in more ways than we know, and maybe it won't be exactly like it was, but the conditions are there fo...

First real-time view of developing neurons reveals surprises, say Stanford researchers

...d University School of Medicine found that neurons come into this world with a good idea about what they'll become as adults. The work, which is detailed in a paper in the March 24 issue of Neuron, took place in the brain of a small see-through fish called a zebra fish. Stephen Smith, PhD, professor of m...

New Breast Cancer Test Could Save Lives

...ut this new technology and the benefits that might come from its use.?/p> This world-leading research project is funded by the United Bristol Healthcare Trust (UBHT), the University of Bristol’s enterprise initiative and the Sulis Seedcorn fund, which recently awarded over £100,000 of venture capital ...

New insight into people who 'see' colors in letters and numbers

...multiple synesthetes and treat them as if they all come from a homogeneous population. "The use of single case studies in synesthesia is also of concern because the results obtained with one synesthete may not generalize to other synesthetes. The researchers concluded that "Our results suggest that syne...

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