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Tag: "combined" at biology news

Failure of 'scout cells' may lead to cancer in transplant patients

...sing healthy human scout cells to TGFb. Next, they combined the scout cells with T cells and PTLD-like cancer cells. The T cells that grew alongside the scout cells exposed to TGFb were significantly less able to kill the cancer cells than were the T cells growing with scout cells not exposed to TGFb. I...

Combined treatment extends life expectancy for lung cancer patients

...es. While this study did not address the timing of combined treatment, brachytherapy radiation was typically a... the only hospital in the world to administer this combined treatment. The recurrence rate was much lower with the combined treatment. With radiation therapy ...

Salk and Stanford teams join forces to reveal two paths of neurodegeneration

...d it hatched the idea to combine our ideas." They combined data collected by Luo's lab in fruitflies with experiments done in mice by O'Leary and co-lead author Todd McLaughlin, a postdoctoral fellow in the O'Leary lab. When cut, axons in mice or fruitflies degenerate quickly. However, in so called Wlds mi...

Scientists reverse evolution

...rformed the jobs of both genes. Mice born with the combined gene still were able to breathe and survive thanks...as redundant, and Hoxd1 plays a minor role. So the combined Hoxa1-Hoxb1 gene performs essentially all the functions of the ancient gene, Capecchi says. A New...

Researchers unveil strategy for creating actively-programmed anti-cancer molecules

...l years precisely because of their long half-life, combined with their overall lack of toxicity and the fact that they can be easily designed and produced. For cancer treatment, the ability of antibodies to direct immune system responses to specific tumor types is one of the factors that have led to their inc...

Precision biochemistry tracks DNA damage in fish

...lls and livers using liquid and gas chromatography combined with mass spectrometry (LC/MS,GC/MS). Precision chemical analysis techniques at NIST allowed the researchers to identify and measure damage to adenine and guanine, specific chemical components or bases of DNA, at extraordinarily low levels--five lesi...

UCLA study finds same genes act differently in males and females

...genes in the liver, and other research has found a combined total of 60 gender-influenced genes in the brain ?about one-tenth of what the UCLA team discovered in these organs. Even in the same organ, the researchers identified scores of genes that varied in expression levels between the sexes. Gender consi...

Statins stop hepatitis C virus from replicating

...rs tested the anti-HCV activities of each one when combined with interferon. Each combination, except the one ...gly effective treatment," the authors report. This combined therapy was more effective against HCV RNA replication than interferon alone and more effective than...

Species unique to tidal marshes face threats

...some 200 member societies and organizations with a combined membership of about 250,000. ...

MUHC announces a transplant first in Quebec

... the MUHC have announced Quebec's first successful combined heart/liver transplant. The patient, Patrice Dionn...nsplants are so rare that the best technique for a combined implantation has not yet been elucidated," says Dr. Kevin Lachapelle, a Cardiac Surgeon at the MUHC,...

Selectively blocking inflammatory signals may protect mice from MS

...tiple sclerosis, this protective approach could be combined with stem cell therapy to repair nerve damage. Several research groups are already studying the use of stem cells to repair damaged myelin sheaths, but in the long term those stem cells would be vulnerable to ongoing immune-mediated damage. But i...

UCLA researchers develop T-cells from human embryonic stem cells

...tance, the technique could be used to treat severe combined immunodeficiency, or the "bubble boy disease," which leaves its victims without a working immune system, forcing them to a life in an antiseptic, germ-free environment. ...

Interfering RNA silences genes in 'slippery' immune cells

... team from The Children's Hospital of Philadelphia combined laboratory technologies in using RNA interference to manipulate human T cells. T cells are immune cells that circulate in the blood, with important roles in autoimmune diseases, infectious diseases and some cancers. "T cells have previously been di...

Patients to benefit from novel technology revolutionizing high-speed molecular imaging

...hybrid image) and in near real time for developing combined single photon emission computerized tomography (SPECT) and CT images," added the co-author of "D-SPECT: A New Solid State Camera for High-Speed Molecular Imaging." "Patient health considerations and radiation safety standards limit the radiation d...

Study challenges myth that sex late in pregnancy hastens birth

... change in the cervix among sexually active women, combined with the lack of difference in delivery dates among the two groups, suggests that sexual intercourse has no effect on inducing labor, Schaffir said. He acknowledged that women who are more comfortable late in pregnancy may be more likely to engage i...

Mobile DNA part of evolution's toolbox

...fornia, Berkeley, postdoctoral fellow Nadav Ahituv combined the human version of the LF-SINE sequence with a "reporter" gene that would produce an easily recognizable protein if the LF-SINE were serving as its on-off switch. He then injected the resulting DNA into the nuclei of fertilized mouse eggs. Eleven d...

Combination therapy shows promising results in patients with advanced lung cancer

...a portion of those may now be able to take Tarceva combined with Celebrex. Because they target what is broken in a cancer cell and leave the healthy cells alone, therapies like Tarceva cause fewer side effects than conventional therapies such as chemotherapy, which targets all fast growing cells and often re...

MRSA vaccine shows promise in mouse study

... later. When they vaccinated the mice using the combined vaccine, however, all of the mice survived. Although unvaccinated mice had clear evidence of kidney infections, the "bacterial load" in vaccinated mice was reduced "to a level below detection." The next step was to test the vaccine's ability to pr...

Scientist works to improve treatment for brain tumors

...protein that regulates the immune system. Debinski combined IL13 with a bacterial toxin to create a cytotoxin drug to target cancer cells and less healthy cells. The efficacy of the first generation of the drug has been has been tested in a clinical trial (phase III) involving 190 patients at 40 different med...

Inheriting a tendency to brain infection

...he results in patients with TB, Casanova hopes the combined treatment could dramatically accelerate recovery from herpes simplex encephalitis, and thereby also limit potential brain damage. Casanova believes there are likely other genes that predispose people to infectious diseases, and that some of them ma...

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