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Tag: "combination" at biology news

Flick of a protein switches immune response

..., the specific expression of a gene depends on the combination of "transcription factors" acting on it. Transcrip...entify single genes that were activated by NFAT in combination with AP-1 and suppressed by NFAT with FOXP3. Beyond shedding light on the immune system, the Cell ...

U of M study examines kidney stone prevention in astronauts

...reases the risk for kidney stone development. "In combination with hydration therapy, exercise in a machine that simulates gravity could reduce the astronaut's risk of developing kidney stones, a condition that could be particularly painful and lead to an aborted mission," Monga said. ...

Tiny shock absorbers help bacteria stick around inside the body

...to a sugar molecule on a surface. The FimH-sugar combination makes a "catch bond" that acts like a finger trap, and actually gets stronger as drag force is exerted on a bacterium. Rather than being swept away by fluids moving through the human body, the bacterium grips even more tightly, helping it stick aroun...

Memory loss affects more of the brain than previously thought

...t these findings together to develop a synergistic combination of memory testing, genetic and imaging studies that together can best predict early onset and monitor progression of AD. "If memory problems are beginning to impact the day-to-day life of you and your family, you should undergo comprehensive testin...

Iron critical to ocean productivity, carbon uptake

...luorescence technology now allows us to tell which combination of nutrients is stressing the phytoplankton." Behrenfeld said the presence of iron stress in the ocean links phytoplankton to the climate through changes in terrestrial-based dust deposited in the ocean, but it is too early to tell if there is an im...

New MRI technique shows emphysema in asymptomatic smokers

...same defects detected with MRI. Moreover, with the combination of MRI and hyperpolarized helium, the researchers were able to measure lung structures with 2½ times more precision than with CT, and 10 times more precision than with conventional MRI methods. Age is a significant factor in the development of emphy...

U of MN uses robotic surgery techniques in cardiac cell therapy research

...the heart and function improved. The team used a combination of skeletal myoblasts, or cells that give rise to muscle, and bone-marrow derived cells. Both cell types have been shown to improve the development of new blood vessels and to improve function of injured heart muscle. Both are in human clinical trial...

Trial success for diabetic nerve therapy

... of glucose on nerves believe it is likely to be a combination of factors. ...

Study shows hope for ridding lakes of clawed invader

...xperiment will expose a "tipping point," where the combination of trapping and pressure from predator fish pushes the rusty crayfish population to crash, with the lake ecosystem returning to its pre-rusty crayfish state. "What we are wondering is whether we will reach a tipping point where the fish alone can k...

Discovery may speed forest biotechnology

...ise, however, the researchers found that the CO/FT combination also controlled the cessation of vegetative tree g...t degree. It also appears that the CO/FT genetic combination is critical to help trees adapt to local conditions, the researchers found. They studied aspen trees...

Oxidation defense in mosquitoes benefits malaria parasite

...ince 2003. "The use of protein crystallography in combination with biochemical studies and medicinal chemistry, represents a highly multidisciplinary approach that could lead to the identification of novel agents for the treatment of malaria," said Rizzi. The PNAS article describes what an International team o...

Inflammation and drugs to control this activity studied in a variety of tumors sites

...ints to the fact that brain tumors are caused by a combination of several environmental, endogenous and genetic factors," he said. "They are not related to one specific cause, but rather, to several that are interplaying with one another to create tumors. We're trying to figure out what those key factors and gen...

AIDS-related cognitive impairment exists in two separate forms

...atively correlated, she said, and when tested, the combination generated a gene expression score that provided a better predictor of relapse than the Gleason score. "This gene expression score appears to give us additional prognostic information that current technology cannot provide, and that will help us treat...

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

...atively correlated, she said, and when tested, the combination generated a gene expression score that provided a better predictor of relapse than the Gleason score. "This gene expression score appears to give us additional prognostic information that current technology cannot provide, and that will help us treat...

A step forward in the fight against bacterial infections

...or bacterial infections. The mutant mice display a combination of important characteristics: they are resistant to LPS, but they still recognize and destroy pathogens. The limited quantity of type 1 interferons enables the mice to cope with a lethal shock resulting from inflammation, but this small quantity also...

Study finds 60 new genes controlled by DNA snippet

...quence of code starting with 2 Cs, followed by any combination of 6 As or Ts, and ending in 2 Gs is a CArG box. According to Miano, there are 1,216 variations of CArG box that together occur approximately three million times throughout the human DNA blueprint. CArG boxes exert their influence over genes becaus...

VCU Massey Cancer Center researchers identify a new class of anti-cancer drugs based on platinum

...ed bladder cancer, and is a very effective drug in combination with other therapies. However, according to Farrell, these current agents have limited activity against many common human cancers, and they are susceptible to acquired drug resistance. He added that resistance to cisplatin has become a clinically r...

FDA approves first medical device using rutgers biomaterial

...c. designs, develops and commercializes innovative combination medical devices and drug delivery products using patent protected tyrosine-derived polyarylates. ...

Nano-particles effective in killing cancer with one-two punch of chemotherapeutics

... of the polymersome properties to ferry their drug combination to the tumor. The large polymers making up the sh...rding to the researchers, the polymersome and drug combination is self-assembling ?the structure spontaneously forms when all of the components are suitably mixed ...

Scientists discover new genetic subtypes of common blood cancer

...e scientists asked whether any specific pattern or combination of these aberrations in an individual patient might help predict how aggressive the disease would be. For this deeper analysis, the researchers created an algorithm based on a recently developed computational method designed to recognize individuals...

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