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Tag: "combination" at biology news

Combination therapy shows promising results in patients with advanced lung cancer

...elp battle resistance and prove to be an affective combination against lung cancer. Typically, about 10 percent ...ents respond to Tarceva. In Reckamp's study of the combination therapy, about 33 percent of patients responded. "Tarceva alone is a great drug and has a lot of cl...

Mouse study reveals new clues about virulence of 1918 influenza virus

... Furthermore, their results suggest that it is the combination of all eight of the 1918 flu virus genes interacting synergistically that accounts for the exceptional virulence of this virus. Michael G. Katze, Ph.D., of the University of Washington School of Medicine, Seattle, a grantee of the National Institut...

Clot-busting drug helps revive cardiac arrest patients

..., have suggested that clot-busting medications, in combination with CPR, may improve overall survival. Bozeman's study is the first in the United States to observe the effects of treatment with tenecteplase and with standard therapy. Tenecteplase was developed and is marketed by Genentech Inc. of South San Fran...

Researchers discover how bacteria sense their environments

...stimuli such as pollutants or explosives. Using a combination of X-ray crystallography to determine the structure of receptors and enzymes and a novel spectroscopic technique for measuring interactions between them, Crane's group was able to develop a model for how the complex of receptors is organized. Jack Fr...

Patients to benefit from novel technology revolutionizing high-speed molecular imaging

... and anatomy, he added. "Simultaneous imaging of a combination of radiopharmaceuticals can be used to define a specific disease signature leading to noninvasive biopsy," he detailed. The D-SPECT camera will provide "a potential breakthrough in organ-specific (heart) SPECT imaging," said George Zubal, SNM's Scien...

Trials for new drug to overcome HIV

... existing antiviral drugs is about to be tested in combination with standard antivirals. Called PA-457, it is the...ded to discover how the drug performs as part of a combination treatment with other anti-HIV drugs, which is a more realistic situation. Fortyeight patients whose ...

'LEGO-Like' building blocks to halt cell growth wins Hebrew University prize

...h a way that they will form an effective medicinal combination and so that they will bind to the receptors of spe...ry, has shown, for example, that with a particular combination of peptides and scaffold design, it is possible to create a synthetic molecule that will bind to the...

Proteins as parents

...roteins with new mechanical properties through the combination of two "parent" protein fragments. The research group of Hongbin Li chose two different titin domains from heart muscle for their experiments. Titin, a giant molecule, is responsible for controlling the passive tension of our muscles and also pulls...

Statins stop hepatitis C virus from replicating

...tis C virus (HCV). They could replace ribavirin in combination therapy with interferon. These findings are publis...are infected with HCV. The standard treatment is a combination therapy of interferon and ribavirin, which is only effective in about 55 percent of patients. The re...

Biofuels researcher searches for new sources

...s for ethanol. Since the jury is still out on what combination of sources will be best to replace petrol, Chen is working with sources that will be more universally available -- especially in Montana. Chen is working on the issue from two directions. First, he is looking at how to maximize the volume of Montan...

Researchers appeal for new regulations to save coral reefs from live fish trade

...in terms of magnitude and geographical spread. The combination of destructive harvesting methods and over-harvesting of large, predatory fish reef fish have devastating effects. Being able to choose a huge fish to eat from a tank is a big pull in luxury seafood restaurants. Fish such as the Napoleon wrasse, a ...

Harmful Algal Blooms monitored from space in Chile

...s onboard satellites. The CAP project utilises a combination of near real-time EO data, such as chlorophyll-a pigment concentration, secchi transparency, suspended matter and sea surface temperature, derived from the MERIS instrument onboard ESA's Envisat satellite and the MODIS instrument onboard NASA's Aqua ...

Smell of success for nanobiosensors

...eact to different odorants and it is the resultant combination of reactions that identifies a certain smell. Nanotechnology makes such an electronic nose feasible, the coordinator notes, even though the human nose uses 1,000 different proteins to allow the brain to recognise 10,000 different smells. While the...

UCSD researchers develop 'smart petri dish'

... drugs may have adverse side effects when taken in combination with another," says Sailor. "You're not supposed t...ink alcohol when taking acetaminophen, because the combination of the two is much more toxic to your liver than either drug individually. This is known as an adve...

Study shows pine bark naturally decreases severe chronic venous insufficiency

... during walking and swelling limbs than Daflon®, a combination of diosmin and hesperidin and a commonly prescribed drug used to treat CVI. About 500,000 people in the United States develop leg ulcers due to CVI. If left untreated, leg and ankle swelling can lead to dangerous conditions such as deep vein throm...

Small molecule interactions were central to the origin of life

...of a molecule that can self-replicate requires the combination of diverse chemicals in a long sequence of reactions in a specific order, interspersed by complicated separations, purifications, and changes in locale. Instead, Shapiro introduces the idea of a "driver" reaction, linked to a free energy source, th...

Surprise finding for stretched DNA

...nd the University of California at Berkeley used a combination of microscopic beads and magnetic tweezers to observe that when a DNA molecule is stretched, it actually begins to overwind. This overwinding continues until the force being applied to stretch the DNA exceeds about 30 picoNewtons. (One picoNewton is ...

Pathway toward gene silencing described in plants

...ted with the genes that match the siRNAs. "The combination of DNA FISH and protein localization allowed us to...duction involving Pol IVa". Pikaard said. A combination of genetic mutants, transgenes, antibodies, RNA-FISH and DNA-FISH were key to the study. "This toolk...

Gene screen for breast cancer better than pathologist's 'eye'

...mel Cancer Center. "It can be a valuable tool, in combination with pathological review, for breast cancer as well as other diseases where fluid can be obtained relatively easily, such as lung, head and neck cancers, pancreatic and cervical cancers." Pathologists look for telltale shapes of cells to determin...

Combination therapy with a monocloncal antibody and a vaccine leads to tumor rejection

...ed that an anti–CTLA4 monocloncal antibody used in combination with a vaccine expressing GM-CSF (Gvax) was able t...sponse to exposure to self-antigen. Interestingly, combination of CLTA4 blockade with Gvax selectively primes the anti-tumor Teff cells for action. This led to gre...

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