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Tag: "colon" at biology news

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...so-called precursor cells within the lining of the colon than normal mice. When these mice also carried a c...fically, this discovery should expand attention in colon cancer research to earlier events, situations present well before tumors appear," says the study's l...

Columbia research lifts major hurdle to gene therapy for cancer

...varian, breast, brain (glioma), skin(melanoma) and colon cancer - because the virus is constructed toexploit a characteristic of all solid cancers."What's exciting is we may now be able to design a therapy that willseek out and destroy only cancer cells," said the study's seniorauthor, Paul B. Fisher, Ph.D...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...ause disease, the level of certain bacteria in the colon can be an important determinant of the amoeba's virulence. Biomedical scientists say the E. histolytica sequence will help researchers develop new tools to predict which of the millions of people who ingest amoeba cysts in contaminated fluids will a...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...s well at inhibiting the migration of prostate and colon cancer cells," said senior researcher Dr. Xin-Yun Huang, Professor of Physiology and Biophysics at Weill Cornell Medical College in New York City. The findings have just been published in Proceedings of the National Academy of Sciences. For decades...

Papers of DNA Pioneer and Nobel Laureate Francis Crick Added to National Library of Medicine’s Profiles in Science Web Site

...his latest article just days before his death from colon cancer on July 28, 2004, at age 88. The online exhibition features correspondence, lecture notes, draft and published articles, laboratory notebooks, and photographs from the Francis Crick collection at the Wellcome Library. Visitors to the site can...

Zebrafish may hold key to understanding human nerve cell development

...tudyvarious clinical disorders including leukemia, colon cancer, congenitalheart defects, muscular dystrophy and other birth defects....

Harmful Bacterium Commonly Found in Poultry May Survive Refrigeration and Frozen Storage Combined

...tudyvarious clinical disorders including leukemia, colon cancer, congenitalheart defects, muscular dystrophy and other birth defects....

GenMAPP 2.0 released

...tudyvarious clinical disorders including leukemia, colon cancer, congenitalheart defects, muscular dystrophy and other birth defects....

Newly Discovered Compound Blocks Known Cancer-Causing Protein

...sts showed they could block the growth of cultured colon cancer cells using this new compound, called cysme...anently activate it have been found in half of all colon cancer and 90 percent of pancreatic cancers, among other cancers. Casey and his colleagues in Duke'...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...ect on the cells lining the innermost layer of the colon (called the epithelium) and causes them to lose co...her molecular player influencing the initiation of colon cancers. This study will be published in the February 1 issue of the journal Genes and Development....

Test for early detection of prostate cancer shows promise

...ncer (12 patients), bladder cancer (six patients), colon cancer (two patients), kidney cancer (one patient), spinal cord injury (seven patients) and noncancerous prostate inflammation (two patients), and 16 healthy individuals. The study was conducted at the University of Pittsburgh while Getzenberg was a ...

Duke engineers develop new 3-D cardiac imaging probe

...e can also be used to image the esophagus, rectum, colon and prostate. A peer-reviewed report on the work was published this month in volume 26 issue number 4 of the journal Ultrasonic Imaging. (Note: Because the journal's publication is backlogged, the issue date is 2004.) The research is funded by the ...

Turning viruses into allies against cancer

...y stimulant called GM-CSF, (granulocyte macrophage colon stimulating factor). Its job is to induce an immune response to any surviving cancer cells released during the initial viral attack, essentially preventing the spread of these cells to other parts of the body. "This aims to treat metastatic disease ...

Researchers find promising cancer-fighting power of synthetic cell-signaling molecule

... and soybeans, suppress tumors in mouse models for colon cancer. Encouraged by these findings, Emory Unive... were also effective in two other mouse models for colon cancer. "We do not know why Enigmols affect such a wide range of tumor cell types," Merrill said. "...

NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses

...lts do not yet have relevance for preventing human colon cancer, they do illustrate the interplay between genes and common nutritional and medicinal agents in development of cancer in the intestines. The drug they tested, sulindac, was a highly effective chemoprevention agent, the researchers say, because...

Red delicious, Northern Spy apples have most antioxidants, chemists find

...a role in the onset of heart disease and prostate, colon and other cancers. Polyphenols ?phytochemicals that act like astringents ?are major sources of antioxidants in apples, but which polyphenols are most active in the fruit has perplexed scientists. Tsao and his colleagues used three different laborato...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

...t anti-angiogenic drugs have a favorable impact on colon and lung cancers,?said NCI Director Andrew C. von Eschenbach, M.D. “This study demonstrates that when patients with recurrent or metastatic breast cancer received bevacizumab in addition to their chemotherapy, the period of time that they lived with ...

MUHC researchers make cancer target breakthrough

...archers document a reduction in the growth of both colon and lung cancer tumors with inhibition of the gene...earchers found that the antisense reduced lung and colon cancer tumors in both laboratory-based tissue cultures and in mice. "Discovering that the antisense ...

Important discovery about second most fatal cancer

...e common in females # More common in right side of colon # Little evidence of tumour immunity # Frequent mu...lation are more likely to have a family history of colon cancer and other types of cancer. Moreover, the colorectal cancers appear to develop in polyps that ...

Natural tumor suppressor in body discovered by UCSD medical researchers

... that PHLPP levels are markedly reduced in several colon cancer and gliobastoma human cell lines that had elevated Akt phosphorylation. Reintroduction of PHLPP into the cell lines caused a dramatic suppression of tumor growth. With additional laboratory tests, the team found that PHLPP stops tumor growth b...

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