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Tag: "coli" at biology news

Lack of a key enzyme dramatically increases resistance to sepsis

...three times more susceptible to lethal Escherichia coli infection than normal mice. Consequently, the study said, sepsis resistance in caspase-12 deficient mice was most likely due to an initial hyper-production of cytokines that fight the infection. "The resulting beneficial effect of cytokine hyper-p...

Common practices at petting zoos put visitors at risk

...lts of a case-control study of an outbreak of E. coli O157:H7 associated with two Florida petting zoos, in which they interviewed visitors who did and did not get sick to identify which behaviors were predictors of infection. Some behaviors that were most strongly associated with illness were feeding ...

Scientists seek to unwrap the sweet mystery of the sugar coat on bacteria

...ab strains of E. coli, one pathogenic strain of E. coli that causes neonatal meningitis, and Salmonella typhimurium, which causes food poisoning. They analyzed each strain of bacteria using lectin microarrays--small glass plates covered with dots of sugar-binding proteins called lectins. The lectin dots ...

Molecule by molecule, new assay shows real-time gene activity

... for the well-studied lacZ gene in the Escherichia coli chromosome. When lacZ's regulatory machinery allows the modified gene to be converted into a handful of protein molecules, these Tsr-Venus hybrids migrate to the cell membrane, where each attaches firmly. The clearly visible flash from each Tsr-Venus...

Removing DNA repair gene causes metabolic syndrome

... clone and crystallize homologs to the Escherichia coli endonuclease VIII gene. E. coli endonuclease VIII is part of a pathway of enzymes involved in repairing DNA damaged by free radicals...

MBL leads effort to update E. coli genome

...ns, are often understood by their similarity to E. coli genes. As such, the accuracy and completeness of ...comprehensive, updated description of all 4,500 E. coli K-12 genes. The data is presented in the January 5, 2006 online issue of the journal Nucleic Acids ...

U-M researchers take new approach to defeating Gram-negative bugs

...his research team genetically modified Escherichia coli bacteria, known as a Gram-negative bug, to weaken ...lague. Woodard and his collaborators worked on E. coli in part because it is one of the more common Gram-negative bacteria, and it is considered by researc...

Evolution follows few of the possible paths to antibiotic resistance

...g how well each variant protected host Escherichia coli cells against treatment with various concentrations of antibiotic, the scientists found that only a very small fraction of these pathways confer ever-increasing resistance in pathogenic microbes, and are therefore relevant to natural selection. Resi...

Researchers discover way to transport environmental arsenic to plant leaves in new clean-up strategy

...inserted two unrelated genes from the bacterium E. coli called arsC and ECS into Arabidopsis, a model lab plant and small member of the mustard family. This allowed the plants to resist the toxic effects of arsenic and sequester three-fold more arsenic in their shoots than normal plants. Still this was to...

Tiny shock absorbers help bacteria stick around inside the body

...witzerland have been studying how the bacterium E. coli attaches to mucous membranes in the body. In their...imbriae also play a key role in the tenacity of E. coli clinging to mucousal surfaces. The tiny fiber-like protrusions are made up of interlocking protein s...

Purdue creates new low-cost system to detect bacteria

...cterial colonies, including salmonella, vibrio, E. coli and bacillus. "We were able to classify bacterial colonies with greater than a 90 percent probability of being correct, which is as good as you could do with equipment costing more than $100,000, " Rajwa said. "And, unlike conventional systems, our...

DNA: Bacteria's survival ration

The ubiquitous bacteria E. coli rank among nature's most successful species for lo...hern California have added another: in a pinch, E. coli can feast on the DNA of their dead competitors. A research team led by Steven Finkel, assistant pro...

Super-sized cassava plants may help fight hunger in Africa

... The researchers used a gene from the bacterium E. coli to genetically modify cassava plants. The plants, ...0s.) They inserted into three cassava plants an E. coli gene that controls starch production. A non-modified fourth plant served as a control. "Cassava act...

Protein clue to tailor-made antibiotics

...t a type of biological warfare. Bacteria like E. coli frequently try to kill each other when resources are scarce using protein antibiotics called colicins, which are potent toxins. The research led by Professor Colin Kleanthous has discovered a critical element in the mode of action of a class of co...

BGSU biologist trying to crack microscopic code

... and his graduate assistants do their work with E. coli bacteria, which he calls "the world's best Lego se...areas. The problem, however, is that laboratory E. coli are the "98-pound weaklings in the real world," not offering barriers as robust as other bacteria ma...

Breaks in hibernation help fight bugs

...el that mimicked the growth of bacteria such as E. coli and Salmonella in European ground squirrels, and how it affected their torpor patterns in relation to temperature. Microbial growth depends on temperature. Most bacteria grow faster when it is warm and much slower when it is cold. For animals ex...

Molecular DNA switch found to be the same for all life

...tor" of DNA replication in a bacteria, Escherichia coli (E. coli), and in a eukaryote, Drosophila melanogaster, the fruit fly. Taken with earlier research that identified AAA+ proteins at the heart of the DNA replication initiator in archaea organisms, these new findings indicate that DNA replication is...

Basic work on E. coli identifies two new keys to regulation of bacterial gene expression

...rase, according to work done with the bacterium E. coli and published today (June 16) in the journal Cell ...isms, and adds to the wealth of knowledge about E. coli contributed by scientists from the UW-Madison. "The kinds of processes that we study in E. coli hap...

Transgenic goat's milk offers hope for tackling children's intestinal disease

...n the small intestine, including fewer Escherichia coli (E. coli), than did the control group of young pig...ilk from non-transgenic goats. Some strains of E. coli can cause severe intestinal illness. However, the kid goats fed lysozyme-rich goat's milk, had hig...

Leptin found to control appetite and limb development in frogs

... they solved those issues and put the gene into E. coli bacteria to make quantities of leptin, the frog protein turned out to be functionally very similar to the human version, Denver notes. "It would appear that leptin and its role as an energy balance indicator has been around a long time," Denver sai...

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