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Tag: "coli" at biology news

The very defensive caterpillar

...r to be able to persist from the initial benign E. coli infection and then confer resistance against the second, usually lethal, infection by the pathogen. Using RNAi techniques workers at the University of Bath have shown that several different proteins can confer this protective effect against subsequen...

'Underground' tunnels discovered as means for communication between immune system cells

... microinjection tip, they squirted a mixture of E. coli fragments into a culture dish, and, indeed, one to...ic cells, macrophages and a small amount of the E. coli mixture in the same culture dish. The dendritic cells, as would be expected, fluxed calcium in respo...

Researchers find how some antibiotics kill bacteria

...d at the effects of rifapentin and rifabutin on E. coli RNA polymerase. With recent advances in X-ray crystallographic studies of RNA polymerase, the researchers could determine exactly where and how both antibiotics bound to RNA polymerase in E. coli, and what it did to that polymerase as a result. The...

Scientists create digital bacteria to forge advances in biomedical research

...nts necessary to search for food. These digital E. coli contain their own chemotaxis system, which transmits the biochemical signals responsible for cellular locomotion. They also have flagella, the whiplike appendages that cells use for propulsion, and the motors to drive them. Emonet and his associates...

Einstein researchers identify new way that bacteria develop resistance to antibiotics

...s similar to MfpA are also present in Shigella, E. coli and other disease-causing bacteria that have developed fluoroquinolone resistance. "Our study shows that this novel bacterial mechanism is responsible for the rapid spread of fluoroquinolone resistance that is making hospital-acquired infections so ...

Hurricane aftermath: Infectious disease threats from common, not exotic, diseases

...r. Although at high levels in floodwaters, the E. coli found in New Orleans is the type commonly associated with fecal contamination and is not the E. coli H7:O157 strain that can cause serious kidney disease and bloody diarrhea. "At this point in time, I...

A step toward the $1,000 personal genome using readily available lab equipment

...line edition of Science. The team sequenced the E. coli bacterial genome at a fraction of the cost of conventional sequencing using off-the-shelf instruments and chemical reagents. Their technology appears to be even more accurate and less costly than a commercial DNA decoding technology reported earlier ...

Study findings offer potential new targets for antibiotics

...hicago. Fredrick provided a strain of Escherichia coli important for the study. In order to find out if ...uced a mutated copy of the ribosomal genes into E. coli cells and looked for those rare mutations that could interfere with cell growth. It was known from p...

DNA size a crucial factor in genetic mutations, study finds

...ural thymine, both in the test tube and in live E. coli bacteria. In contrast to this, the smallest and largest analogs in the set were rejected by the enzyme and the bacteria. According to Kool, these results indicate that size is a strong factor determining enzyme efficiency-and a mechanism for allowi...

A bug's life: Exceptional genomic stability yet rapid protein evolution in a carpenter ant mutualist

...nd translocation. In comparison, the genomes of E. coli and Salmonella, which diverged between 100-150 million years ago, have undergone extensive changes in their genomic architecture. Interestingly, the observations of Wernegreen regarding B. pennsylvanicus were consistent with those previously describe...

Student scientists create living bacterial photographs

...ing Petri dishes full of genetically engineered E. coli instead of photo paper, students at The University...gical film"--billions of genetically engineered E. coli growing in dishes of agar, a standard jello-like growth medium for bacteria. Like pixels on a comp...

War on terror meets war on cancer

...tside a cell," Hegg says. The researchers grew E. coli bacteria at body temperature in flasks containing ... 30 percent of the water inside rapidly growing E. coli came from outside the bacteria and 70 percent of the water was produced by metabolism inside the bac...

Zooming in on the protein-conducting channel

...chers created a complex comprising the PCC from E. coli attached to a ribosome that contained a newly forming protein segment. The ribosome is the massive protein-RNA complex that constitutes the cell's protein-making machinery. Mitra explored the structure of this PCC-ribosome complex using three-dimens...

Novel protein complex enables survival in hostile environment

... an energy transduction system is also found in E. coli and humans," Mukhopadhyay said. "Fsr-C is similar to the sulfite reductases that are found in certain bacteria and archaea. These previously described sulfite reductases do not use coenzyme F420 as the electron source and are also not tethered to the...

Free-energy theory borne out in large-scale protein folding

...tein, or MLAc, a variant of the protein used by E. coli to regulate expression of the proteins that transport and metabolize lactose. MLAc contains about 360 amino acids. While scientists know proteins containing 100 or fewer amino acids fold in a very cooperative (all-or-none) fashion, it is believed th...

How E. coli bacterium generates simplicity from complexity

The ubiquitous and usually harmless E. coli bacterium, which has one-seventh the number of gen...tional Academy of Sciences (PNAS) that Escherichia coli doesn't gamble with its metabolism. In a surprise about E. coli that may offer clues about how hum...

Worms know bad food when they smell it

... had been exposed only to a harmless strain of E. coli for their entire lives. The other two groups had ...s. When the worms that had been grown only on E. coli were later introduced to pathogenic bacteria (either P. aeruginosa or S. marcescens ), they were ...

Pair of studies offer new clues to combat antibiotic resistance

... in Germany genetically engineered a strain of E. coli so that it lacks its normal outer protective laye...ack. Removal of this layer is believed to make E. coli and other gram-negative bacteria more vulnerable to antibiotic attack, the scientists say. "The st...

Rochester scientists develop fast-working biosensor

...tects the meat-spoiling and sometimes dangerous E. coli bacteria. The unique technology uses a protein fr...seen as a "molecular harpoon," Miller said. The E. coli sends out the harpoon into a cell. Once it is in the cell, the Tir then binds with an E. coli protei...

Common bacteria pirate natural mechanism to get inside cells

...ommon bladder infection-producing uropathogenic E. coli as a model to show how nitric oxide unwittingly as...erial uptake and survival. "In bladder cells, E. coli uses this mechanism to get inside the cells and hide from the antibiotic effect and the immune syste...

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