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Tag: "cofactors" at biology news

Novel Enzyme Shows Potential As An Anti-HIV Target

...e acetylation controls transcription by recruiting cofactors required for transcription. Acetylation and deacetylation enzymes can also target other proteins. Of the three classes of deacetylases known to modify human histones, the sirtuins (SIRT1?) appear to preferentially target a number of nonhistone prote...

An HIV Protein Plays a Surprising Role in Gene Activation

... the TATA-box-binding protein, or TBP) and several cofactors called TBP-associated factors (TAFs). PIC assembly sometimes also requires activator proteins, which can enhance transcriptional activity by supporting proper elongation of nascent transcripts. Tat, an activator encoded in the HIV genome, is require...

PCRM develops world's first cruelty-free insulin assay

...for calf serum--basically a synthetic formula with cofactors and trace elements that promote cell growth. Then, in collaboration with Linco Research of St. Charles, Missouri, Even successfully incorporated antibodies grown in the medium into a test kit for human insulin. A report on the new methodology will b...

Microreactor efficiently regenerates cofactors for biocatalysis

...is the continuous regeneration of molecules called cofactors that permit the synthesis through inexpensive and ...eloped a microreactor that efficiently regenerates cofactors through enzyme-catalyzed reactions. "Enzymes are nature's catalysts, but in some cases, enzymes can...

Cholera pathogen reveals how bacteria generate energy to live

... of the cell membrane. The results showed that the cofactors ?important parts of the enzyme’s machinery ?are all located on the inner side of the membrane, which corresponds to the "intake" port of the ion pump. The second paper was published in the Journal of Biological Chemistry. In this study, Barquera f...

MIT biologists solve vitamin puzzle

... holding electrons and then giving them away. Such cofactors are not consumed in the reaction. Cannibalization of a cofactor has very rarely been observed before in vitamin synthesis or any type of biosynthetic pathway, says Michiko Taga, an MIT postdoctoral fellow in Walker's lab and lead co-author of the ...

Beyond the DNA: Chemical signatures reveal genetic switches in the genome

...he target gene - to which transcription-activating cofactors bind. According to LICR's Dr. Bing Ren, the study's senior author and assistant professor at UCSD's Department of Cellular and Molecular Medicine, the method is widely applicable and its unbiased approach is likely to yield new information on gen...

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(Date:7/10/2014)... open ocean as a microbial megacity, teeming with life ... water, hundreds of types of bacteria can be found. ... ocean microbes have their own daily cyclesnot unlike the ... up, commute, work, and eat at the same times., ... photoautotrophsbacteria that need solar energy to help them photosynthesize ...
(Date:7/10/2014)... if you are a big, bad sea scorpion. , ... waters for any prey in sight. The next, thanks ... you,re reduced to trolling for weaker, soft-bodied animals you ... of the giant pterygotid eurypterid, the largest arthropod that ... in the journal Biology Letters , dramatically re-interprets ...
(Date:7/10/2014)... JUPITER, FL, July 10, 2014 Amidst the astounding ... of synaptic connections in the brain, how do nerve ... connections to build? How do they coordinate these events ... scientists from the Florida campus of The Scripps Research ... processes, showing that a particular protein plays a far ...
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(Date:7/10/2014)... widespread across the United States, due in large to ... of clinical data that will become available for research ... experts in healthcare have become increasingly focused on clinical ... purpose of gleaning insights that have the potential to ... that is known as big data. ...
(Date:7/10/2014)... Adults with dyslexia are more likely to report that ... people who don,t have the learning disorder, according to ... to 10 percent of people, causes problems with reading ... with this condition said they suffered physical abuse during ... dyslexia. "Even after accounting for age, race, sex ...
(Date:7/10/2014)... News) -- Men who have a vasectomy may be ... study suggests. But the risk is comparatively small, ... the study said more research is needed to determine ... the study, Harvard researchers analyzed data from more than ... starting in 1986. During that time, 6,023 cases of ...
(Date:7/10/2014)... 2014In response to today,s announcement that the "Mississippi Baby," ... now been found to have detectable levels of the ... disappointment in this setback but remains hopeful that the ... remain undetectable for more than two years will continue ... ultimately develop a cure. , "Although we had ...
(Date:7/10/2014)... device developed at the Massachusetts General Hospital (MGH) Center ... can be cultured to establish cell lines for genetic ... issue of Science , an MGH research team ... genetic mutation over time and changing susceptibility to therapeutic ... the blood that represent those present in metastatic deposits, ...
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