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Tag: "coded" at biology news

Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation

...in building blocks. Each protein building block is coded by a specific gene. sjTRECs form during a "mix-and-match" rearrangement of these genes into any one of countless combinations. The rings represent sections of DNA cut out of chromosomes during the mixing and matching of genes that are chosen to build...

Family trees of ancient bacteria reveal evolutionary moves

...s ?a thick-walled cell occurring at intervals?were coded and mapped on the tree. The distribution of traits was compared with those found in the fossil record. Cyanobacteria emerging some two billion years ago were becoming complex microbes that had larger cell diameters than earlier groups ?at least 2.5 ...

Multi-purpose protein regulates new protein synthesis and immune cell development

...ch are deposited in the ER membrane in response to coded instructions from genes. Chaperone proteins fold these amino acid chains into specific shapes and direct them to different areas of the ER for processing. When too many amino acids pile up in the ER membrane, or when something goes wrong with the fo...

U of T researchers map role of Epstein-Barr virus in cancer

...he molecular details that show how a viral protein coded in the Epstein-Barr virus immortalizes cells and c...ncer, nasopharyngeal carcinoma. EBNA1 is a protein coded in the Epstein-Barr virus and suspected to play a role in the development of cancer," says Lori Frap...

Discovery could be key to bioterrorism defense

...cademy of Sciences. "We identified genes that are coded for known and predicted cell surface proteins that were missing from the resistant cell line," Dr. Broder said. "The genes were put into cells that were then exposed to a live virus at AAHL." Hendra virus was first isolated in 1994 when an outbreak ...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...come "factories" for the production of the protein coded for by the inserted DNA. As it turned out, this was the case as well for the transferrin/G-CSF combination. "Our recombinant fusion protein was administered orally, and when tested in mice, increased the white blood cell count for three days, where...

Scientists focus on 'dwarf eye'

...P completely wipes out the function of the protein coded for by the gene. In people with this condition, the retina is too close to the lens, but the lens and cornea, the eye's outermost layer, are of normal size and shape. "Eyes with nanophthalmos still work quite well, despite these complications," sai...

Rutgers to lead $52.7 million protein research program

...ome Project. However, the majority of the proteins coded by the genome have unknown functions and unknown structure. For the past five years, Montelione and his consortium partners, including researchers at Columbia University, conducted a $36 million NIGMS pilot program to develop new methods and tools t...

Molecular research suggest shift needed in how some drugs are created

...nate immune systems -- an inherent immune response coded by DNA in all living things -- that are crucial for survival against pathogens such as bacteria and fungi. Deficiencies in the system or an over-active response can set the stage for various infections, septic shock and numerous autoimmune disorders....

Key brain regulatory gene shows evolution in humans

...t, the researchers found that the DNA segment that coded for the PDYN protein itself -- as well as other sites spread around the genome -- showed evidence of "negative selection" that would preserve their original structure. A key experiment, said Wray, was a laboratory demonstration that such regulatory ...

Scientist uses form to explain function of key building blocks of life

...ins are the basic building blocks of life, and are coded for by the genes in DNA. We'd like to be able to start with a gene sequence and predict the structure of a protein and its function. In this case, given an NMR pattern, we can tell you how the protein will act. In general, this method may provide i...

Powerful new tool for studying brain development

...es the blueprint the cell uses to make the protein coded for by that gene. The BGEM links these images with the most up-to-date information on those genes, such as their function, location on chromosomes and exact DNA sequence. The BGEM gathers this information through direct links to the scientific datab...

Rutgers researchers find fat gene

...ktrack along the path to its origin ?the gene that coded it ?linking the enzyme to the yeast gene PAH1 that made it. Carman and his group went on to confirm the link by introducing the yeast gene into bacteria, with similar results. The researchers showed that the enzyme encoded by the PAH1 gene looks and...

Key gene controlling eye lens development identified

...The St. Jude team further showed that the proteins coded for by Six3 are present in the PLE before those coded by Pax6. This was evidence that production of Pax6 proteins in that region of the head starts after ...

Clue found to Epstein-Barr virus' ability to form and sustain tumors

...n, the first step in the process by which a gene's coded information is converted first into RNA and then into protein. Mutating the unique segment of amino acids prevented EBNA-1 from transforming resting B cells into proliferating cells. Under normal conditions, a cellular protein binds this 25-amino...

Discovery of the first resistance gene to rice yellow mottle virus

...to be the eIF(iso)4G translation initiation factor coded by the Rymv1 gene which is probably involved in viral protein translation, but also perhaps in other processes such as the virus's movement within the cell. The research team discovered mutations of the gene they analysed in three different resista...

Cracking the egg

... of mouse egg cDNA. The cDNA fragments are reverse coded from messenger RNA and therefore indicate which genes are being expressed. They identified 5,400 active genes in the fully grown egg, about a tenth of which are unique to egg cells. Interestingly, the process of getting ready for fertilization requir...

Why don't all moles progress to melanoma?

...ds are deposited in the ER membrane in response to coded instructions from genes. Chaperone proteins fold these amino acids into specific shapes. When too many of them build up in the membrane, or when something goes wrong with the folding process, the system gets bogged down. This can stress or even kill ...

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