Defective Gene Linked to Two Inherited Immune Deficiencies
... us to better diagnose these patients, it provides clues to key biochemical pathways that can lead to immunodeficiencies.?/p> The study was led by Raif Geha, M.D., and Emanuela Castigli, Ph.D., of the Children’s Hospital Boston. The Boston team found specific mutations in a gene known as TACI, which pl...U-M scientists discover identifying markers for primitive blood-forming stem cells
...lood-forming organs will give scientists important clues to how they work, according to Morrison. For this reason, the identification of markers that allow the localization of HSCs in tissues has been a long-sought goal in the field of hematopoiesis. "Until this study, we didn't know exactly where to look...Molecular Partners Required For Appropriate Neuronal Gene Repression
...eases and conditions. The findings offer important clues about why the nervous system fails to repair itself and suggest ways that at least some forms of brain damage could be reversed. The research is published in the August edition of the scientific journal Nature Medicine. "For many years, scientists h...OHSU researchers discover potential mechanism to repair brain damage linked to Multiple Sclerosis
...eases and conditions. The findings offer important clues about why the nervous system fails to repair itself and suggest ways that at least some forms of brain damage could be reversed. The research is published in the August edition of the scientific journal Nature Medicine. "For many years, scientists h...Exercise aside, genes may ultimately dictate seniors' mobility
...dy composition the genotype creates also may yield clues to what causes mobility limitations to develop with age, and what people can do to stay active, Pahor said. Those with the II genotype, for example, tended to have higher total body fat. "The good news is that regardless of genotype, the physically ...Researchers Discover Gene That Determines Asthma Susceptibility By Regulating Inflammation
...ody’s defense mechanisms to stress, which may hold clues to better control the inflammation process and improve control over asthma and its symptoms. Study coauthor Tirumalai Rangasamy, PhD said that the next step for researchers will be to look for molecular mechanism of regulation of asthmatic inflammati...Infectious disease expert warns of spread of Rocky Mountain spotted fever
...mined the patients' home environments for possible clues to the source of infection, they found fever-infected ticks in all patients' yards. Ticks were found in the cracks of stucco walls on patients' homes, in crawl spaces under these homes and on furniture placed outside for children and pets. All patien...Variant prion protein causes infection but no symptoms
...ative diseases develop and it provides tantalizing clues as to how we might delay or even prevent such diseases by preventing certain cellular interactions," notes NIAID Director Anthony S. Fauci, M.D. A paper describing the research was released online today by the journal Science. RML virologist Bruce Ch...Evolution of life on Earth may hold key to finding life in outer space
...ow life evolved on Earth is important in obtaining clues as to where else in the universe one might find life and what it might be like, said George E. Fox, a UH professor of biology and biochemistry. Fox is finishing work on a three-year research grant from NASA's Exobiology Program that seeks to understa...Gradient guides nerve growth down spinal cord
... It may also prove a boon to clinicians, offering clues about how to grow new connections among neurons to...nnected during embryonic development could give us clues about how to repair damaged connections in adults with traumatic injury or degenerative disorders," ...Simple explanation for complex pattern of feather development
...nhibitor pair. Prum is now following up on several clues in the search for these other molecular signals. ...Muscle repair: Making a good system better, faster; implications for aging, disease
...ogen system works in skeletal muscle may give some clues to improving repair of different tissues, especially heart, which is similar in many ways to skeletal muscle. ...Genome Sequence for Haemophilus Influenzae Completed
...leagues, examined the structure of these hairs for clues to their exceptional insulation abilities. They found that the cuticle surface structure of the underhairs and base of the less-abundant guard hairs are distinctively shaped to interlock, with wedge-shaped fins or petals fitting into wedge-shaped gro...Otter adaptations: How do otters remain sleek and warm
...leagues, examined the structure of these hairs for clues to their exceptional insulation abilities. They found that the cuticle surface structure of the underhairs and base of the less-abundant guard hairs are distinctively shaped to interlock, with wedge-shaped fins or petals fitting into wedge-shaped gro...Discovery suggests why stem cells run through stop signs
...he University of Washington offer one of the first clues as to why stem cells ignore stop signs in the cell cycle: a special molecular mechanism has cut the brakes. The researchers found that tiny bits of genetic material called microRNAs are necessary for stem cell division to take place, suggesting that ...Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance
...05, issue of the journal Nature Genetics, offering clues to the oncogenic potency of several genes implicated in the development of melanoma. Melanoma is the deadliest form of skin cancer, resulting from the malignant transformation of cells called melanocytes. Over the past four decades, the incidence of......05, issue of the journal Nature Genetics, offering clues to the oncogenic potency of several genes implicated in the development of melanoma. Melanoma is the deadliest form of skin cancer, resulting from the malignant transformation of cells called melanocytes. Over the past four decades, the incidence of...Engineered skin offers clues to melanoma development
...05, issue of the journal Nature Genetics, offering clues to the oncogenic potency of several genes implicated in the development of melanoma. Melanoma is the deadliest form of skin cancer, resulting from the malignant transformation of cells called melanocytes. Over the past four decades, the incidence of...MicroRNA tweaks protein that controls early heart development
... important proteins. The discoveries could provide clues important to understanding both stem cell biology ... determine what they had in common, hoping to find clues to help predict unknown targets in mammals. He then used those criteria to search the entire mouse g...'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes
...king. The subjects also provided other more subtle clues that their attention had reflexively shifted in the direction of the monkey-image gaze, said Platt. An instant after the monkey images appeared, the subjects showed infinitesimal, involuntary eye movements in the same direction the monkey image was l...