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Tag: "clues" at biology news

Protein connections: A network to understand disease

...around the world. Now, the same concept provides clues to unraveling the mystery of how different mutations in different genes can cause diseases with very similar characteristics. In a paper in today's edition of the journal Cell, scientists from Baylor College of Medicine and Harvard Medical School des...

Researchers link two more genes to sudden infant death syndrome

... episodes, unexplained seizures that might provide clues and prevent more deaths." Other researchers involved in the CAV3 study were from the University of Wisconsin-Madison and Baylor College of Medicine, Houston. Researchers involved in the RyR2 study were from Columbia University, New York. ...

Researchers identify human DNA on the fast track

...ama. "The downside is that we don't have many good clues as to how it functions." Haussler's team is now following up on the clues that they do have. Other DNA regions produce stable RNA structures that have a variety of functions ...

UF scientists restore sight to chickens with blinding disease

...nths after a child is born. "There are only a few clues that an infant may have this disease," Semple-Rowland said. "Often parents will notice that their child doesn't seem to be smiling at or looking at faces. Children may also poke or rub their eyes, behaviors clinically known as oculo-digital signs tha...

U of M researchers discover genetic key to treating deadly fungal infections

...hromosomes, which means that the finding may yield clues about how some tumors become resistant to chemotherapy and how researchers can develop companion drugs that inhibit the development of that resistance. About 25,000 Americans develop these fungal infections each year. And in spite of treatment wi...

Adult stem cells are touchy-feely, need environmental clues

...natural regenerative mechanism, depend on physical clues from their local environment in order to transform into different types of tissue. The researchers were even able to manipulate stem cells by changing the firmness of the gel on which they were grown. The researchers believe that their findings, wh...

Parkinson's disease mechanism discovered

.... Lindquist also said the findings give important clues to why dopamine-producing neurons in the brain are the most vulnerable neurons to toxic alpha-synuclein accumulation. The death of such neurons reduces brain dopamine levels, causing the tremors and other symptoms of Parkinson's disease. Dopamine is ...

Queensland scientists identify molecule that links both sides of the brain

...elen Cooper said her group's research provided new clues regarding development of the corpus callosum, the main connecting nerve tract that shuttles information between the left and right hemispheres of the adult brain. Using a mouse model, neuroscientists at The University of Queensland ?working with As...

Mitochondrial DNA sequencing tool updated

...e. As early as the 1920s, scientists uncovered clues that mitochondria might play a role in causing cancer. But like the other DNA in the cell nucleus, scientists lacked the needed research tools throughout most of the 20th century to systematically study the chemical composition of the mitochondrial ...

New genes implicated in rheumatoid arthritis

Researchers continue to search for genetic clues into rheumatoid arthritis (RA), a chronic inflammatory joint disease. While its specific cause is not yet known, RA has been linked to an inherited susceptibility. Interestingly, despite its strong genetic component, RA's occurrence among siblings ...

UAB researchers confirm HIV-1 originated in wild chimpanzees

... southern Cameroon. The findings provide important clues to how the disease migrated from non-human to human primates, and will be released Thursday (May 25) in ScienceExpress [ http://www.sciencemag.org/sciencexpress/recent.dtl ] and will be published in an upcoming issue of Science magazine. Although re...

New potential drug target in tuberculosis

...agram of its building plan - has yielded important clues about its activity. Qingjun Ma from Wilmanns' group purified LipB and obtained crystals of the molecule. Using the high-energy synchrotron radiation beamlines at EMBL Hamburg, on the campus of the German Electron Synchrotron Radiation Facility (DESY)...

Researches discover gene critical for protection against septic-shock-induced death

...anisms to sepsis and septic shock, and may provide clues to designing novel therapies that could minimize mortality. The researchers are now trying to find if activation of Nrf2 by a small-molecule drug can minimize pathological damage and improve survival during sepsis caused by bacteria or viruses. Futur...

Alaska seal pup diet may hold key to decline of population

...nutritionally stressed may not reproduce, offering clues to why some harbor seal populations are falling, Polasek said. Next steps The seals will continue their low fat and high fat diets as the longitudinal research continues. "We're curious to find if it will take longer for the low fat diet animals...

Biomarkers may hone anti-aging therapies

...ondrial genome changes. "Unraveling the molecular clues as to why aging cells function differently than young cells requires that we have molecular markers that we can track," Sligh said. "It won't be long before other investigators who have other human tissue specimens -- brain, lung, heart, for example ...

Thinner and younger

...lso increased. The CALERIE study hopes to get some clues about whether calorie restriction might do the same thing for humans. "We want to learn whether calorie restriction can reverse some of these markers of aging in healthy young people," Holloszy says. "It's going to be many years before we know wheth...

Study fishes out new role for prostaglandins

... the drug discovery process and give us some early clues about the effects we may see in humans," DuBois said. ...

Unraveling the viral mechanism

...itself. The shape of these "tail" structures gives clues about how the virus or phage and cell interact. Then as Chiu and Jiang used the computer visualization tool to strip away the surface shell entirely, they saw the concentric coil of DNA underneath. They also identified a protein "hub" through which ...

Don't hold your breath: Carp can manage without oxygen for months

...some animals cope with a lack of oxygen might give clues as to how to solve this problem in humans. "Anoxia related diseases are the major causes of death in the industrialized world. We have here a situation where evolution has solved the problem of anoxic survival millions of years ago, something that m...

Molecular force field helps cancer cells defend against attack

...tients, we look at their tumors and we try to find clues to why their tumors grow, why their tumors spread, and we look at the various genes and proteins that make their tumors what they are," Cance said. "So from the patient's standpoint, the more that we can characterize their tumor and understand why it...

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