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Tag: "clues" at biology news

Genomic Analysis Uncovers New Targets for HIV Vaccine

...n more polymorphisms that could provide additional clues how some patients are better able to control the virus than others," Goldstein. "This should ultimately lead to novel targets for vaccines, the primary goal of CHAVI." Two of the polymorphisms found were in genes controlling the human leukocyte anti...

Brain holds clues to bipolar disorder

Looking into the brain is yielding vital clues to understanding, diagnosing and treating bipolar disorder, according to findings being presented today at the Seventh International Conference on Bipolar Disorder. Two studies, featured in a press briefing held at 12:15 p.m., Thursday, June 7, have ...

Ancient DNA traces the woolly mammoth's disappearance

Some ancient-DNA evidence has offered new clues to a very cold case: the disappearance of the last woolly mammoths, one of the most iconic of all Ice Age giants, according to a June 7th report published online in Current Biology, a publication of Cell Press. DNA lifted from the bones, teeth, and ...

Research finds that circadian rhythms dominate all life functions

...ding gene oscillation may provide researchers with clues for developing ways to treat people who overeat because of impaired leptin signaling. Circadian rhythms are biological rhythms that cycle over a period of about 24 hours and regulate timing for most physiological functions and behaviors such as sle...

Salk scientists hammer out a pathway that promotes muscle cell survival in mice

...his pathway affects cellular responses may provide clues for improving cellular health in diseases affecting muscle and other cell types. "In addition to muscle, this regulatory circuit is present in brain and heart tissue, where it also seems to control cell survival," said Marc Montminy, M.D., Ph.D.,...

Gene malfunctions cause schizophrenia, depression symptoms in mice

...ant drugs on the two mutant strains "might provide clues to effective medications for these patient groups. Indeed, these mice could represent a model system to explore novel treatment and preventative strategies for certain symptoms of major mental illness," they wrote. "We have shown that two independ...

Anthrax paralyzes immune cells with lethal toxin, UF research shows

...ate. "Together, these studies provide important clues about how anthrax escapes the immune system during infection," said Nick Duesbery, Ph.D. deputy director for research operations and senior scientific investigator at the Van Andel Institute in Grand Rapids, Mich. In 1998, Duesbery discovered that...

Dinosaur hearing, listening to muscle noise, quieter cubicles

... of 36 cat species' middle ears, which may provide clues on the evolutionary pressures on them (2aAB4). LISTENING TO MUSCLE NOISE Muscles make noise. For example, you can hear the sound of the masseter muscle--a jaw muscle used in chewing food-by propping your head (ear down) in the palm of your ha...

From the deep -- Researchers find new species of sea anemone

... the species itself and, more broadly, may provide clues on how human activities affect this unique, seemingly removed ecosystem. "The thing about these communities is that they seem so ephemeral and so unplanned," Daly said. "A whale dies where it dies, and its carcass lands wherever. But these are act...

Decoding protein structures helps illuminate cause of diabetes

... between remain somewhat of a mystery and may hold clues to what drives the transition, says UW-Madison chemistry professor Martin Zanni, who led the new study. In trying to understand diabetes, "people have been looking at the fibers, but they should be looking at their formation," he says. "Somehow t...

UCLA study uncovers clues for why Graves' disease attacks the eyes

UCLA researchers have uncovered new clues that may explain why Graves?disease (GD) attacks the muscle tissue behind the eyes, often causing them to bulge painfully from their sockets, as in the late actor Marty Feldman. Scientists at UCLA’s Jules Stein Eye Institute and Harbor-UCLA Medical ...

Corals that can fight global warming may one day help fragile reefs

...eas], and we should look to these hardy corals for clues that might enhance others," said Harvell. "Other corals are more sensitive and will not survive the continued warming trend." Yet there seems to be future promise for boosting the immunity of coral reefs, Harvell reported. Collaborators Rotem Effro...

Leeches ferry infection among newts

...g to biologists, who say the discovery may provide clues to disease outbreaks in amphibians. The findings could also lead to a better understanding of diseases affecting humans, such as malaria, chagas disease and sleeping sickness. All these diseases are transmitted through a vector, an organism that spr...

Natural antibiotics yield secrets to atom-level imaging technique

...eveal how it sits in the cell membrane," providing clues for modifications that might make synthetic AMPs even more effective in overcoming ever-increasing bacterial resistance. For instance, rearranging parts of the molecule might make it fit into the membrane better, resulting in greater effectiveness wi...

Scientists learn the origin of rogue B cells

...edical Research Foundation, have provided some new clues into one likely factor: the early development of immune system cells called B cells. B cells are formed in the bone marrow and produce antibodies. Antibodies are generated from the cutting and splicing of immunoglobulin genes early in B-cell develop...

McBride shows DNA detective work with paper-eating bacteria that 'glide'

...mplete genome for C. hutchinsonii will yield other clues to the interconnections among gliding bacteria. He is now collaborating with DOE to sequence the entire genome of F. johnsoniae, which will allow a full comparison of the genes of the two microorganisms. ...

Genetic pathways to curable and incurable forms of pancreatic cancer identified

...ncreatic ductal adenocarcinoma in hopes of finding clues to developing early detection biomarkers and possible treatments to halt the progression of the disease. The work involved activating the pancreatic cancer oncogene called Kras and then selectively mutating tumor-suppressor genes such as p53, p16 and...

Technology reveals 'lock and key' proteins behind diseases

...se transporters function and help researchers gain clues for fighting disease and drug resistance." Using iMYTH, the Stagljar lab identified six proteins that interact with and presumably communicate with the ABC transporter Ycf1p, a yeast version of the human proteins CFTR and MRP. These newly discov...

Blame the brain for high blood pressure

...ow to target them. JAM-1 could provide us with new clues as to how to deal with this disease. ? Professor Jeremy Pearson, Associate Medical Director of the British Heart Foundation, commented: “This exciting study is important because it suggests there are unexpected causes of high blood pressure related...

Infection detectives use disease 'fingerprints' to track common infections in children

...ren. Traditionally, researchers have looked for clues to an infection by tracking down the virus or bacteria causing it. But that doesn’t always work because the bacteria or virus may not be present in the blood or other easily accessible area. Researchers at UT Southwestern, Children’s Medical Cente...

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