Nature provides inspiration for important new adhesive
...tand so much force." Li decided to look much more closely at the chemistry of the mussels' byssus, which are small threads that attach them to rocks and other surfaces. The byssus thread is a protein with a very unusual composition - an abundant level of a phenolic hydroxyl group and an amino group - that r...15-year hunt finds cause of pseudothalidomide syndrome
...collaborated with us, they've worked with us quite closely to help us uncover the gene behind the syndrome," says Gordillo. "Now we have about 10 affected families from outside Bogotá, and we can offer a genetic test to families at risk of Roberts syndrome." Vega and Gordillo, a husband-and-wife team, criss...Future diabetes drugs may target new protein interaction
... now probing the pyruvate-sirtuin1 connection more closely and looking for more details of the sirtuin1-PGC1 interaction. Also on the to-do list: examining sirtuin1 and PGC1 in other tissues, particularly muscle and fat, two other energy-producing tissues in mammals. The study was funded by the Ellison Medi...'Smart drug' targets deadly brain cancer
...f a specific tumor protein, p70s6 kinase, which is closely associated with the drug target molecule. Knowing that this protein is a key player in the chain of events that determines drug activity could be useful in screening patients to help determine the best candidates for the drug. Says Dr. Galanis, "Thi...... now probing the pyruvate-sirtuin1 connection more closely and looking for more details of the sirtuin1-PGC1 interaction. Also on the to-do list: examining sirtuin1 and PGC1 in other tissues, particularly muscle and fat, two other energy-producing tissues in mammals. The study was funded by the Ellison Medi...Sugar beet virus mutation requires Texas touch
...as found about the same time. The two viruses are closely related, Rush said. But rhizomania is devastating and found worldwide, while the mosaic virus is not as destructive and is limited to the United States. Growers, breeders and industry officials from Colorado, Nebraska, Wyoming, Idaho, Minnesota, Mic...Computational verification of protein-protein interactions by orthologous co-expression
... now probing the pyruvate-sirtuin1 connection more closely and looking for more details of the sirtuin1-PGC1 interaction. Also on the to-do list: examining sirtuin1 and PGC1 in other tissues, particularly muscle and fat, two other energy-producing tissues in mammals. The study was funded by the Ellison Medi...Eliminate Data Analysis Bottlenecks in Drug Discovery
... now probing the pyruvate-sirtuin1 connection more closely and looking for more details of the sirtuin1-PGC1 interaction. Also on the to-do list: examining sirtuin1 and PGC1 in other tissues, particularly muscle and fat, two other energy-producing tissues in mammals. The study was funded by the Ellison Medi...Researchers find gene that may be at root of potato blight
...ly look like fungi, on a molecular level they more closely resemble algae. Over the last 75 years, potato breeders have introduced at least a dozen late blight-resistant genes into the cultivated potato. The researchers looked at one of these genes, R3a. Kamoun and his colleagues thought that if a potato p...WHO suspends Marburg work, appeals for new funds
...ch have been seen during previous outbreaks of the closely related Ebola haemorrhagic fever. Two medical anthropologists are already in Uige and will be joined shortly by experts in social mobilization from Angola, the Democratic Republic of Congo, and Mozambique. Public compliance with control measures is n...NHGRI targets 12 more organisms for genome sequencing
...aluable comparison with other insects, such as the closely related insect, Rhodnius prolixus. Another insect, the parasitoid wasp Nasonia vitripennis, is a natural enemy of houseflies, and its relatives are natural enemies of ticks, mites, roaches and other arthropods. It is the genetic model for parasitoid...Penn Researchers Use Robotic Surgery
...nder allows surgeons to see the surgical site more closely than human vision allows, and to work at a smaller scale of detail than conventional surgery permits. Unlike other endoscopic systems now in use, which afford reverse-image views that require counter-intuitive movements by surgeons (whereby the surge...Two new retroviruses—transmitted from animals—identified
...nder allows surgeons to see the surgical site more closely than human vision allows, and to work at a smaller scale of detail than conventional surgery permits. Unlike other endoscopic systems now in use, which afford reverse-image views that require counter-intuitive movements by surgeons (whereby the surge...An (ecological) origin of species for tropical reef fish
.... What explains the evolution of a huge number of closely related fish species on reefs in an open undersea ... fact that evolutionary partitions correspond more closely to habitat type, rather than to conventional geographical barriers, indicates that local speciation ...Venom doc tracks down snake bioweapons
...th of these toxin types, CRISP and kallikrein, are closely related to toxins called helothermine and gilatoxin, which are produced by the Beaded Lizard and the Gila Monster, respectively. One of the toxins in this study (called the waglerin peptide) did not exhibit any similarity to known proteins. Fry beli...Innovative coating could give medical implants a longer life
... creating peptoids -- synthetic molecules that are closely related to the natural proteins or peptides they mimic but don't degrade in the body. Messersmith and Barron wanted to use this durability of peptoids to the antifouling coating's advantage. They proceeded to intelligently design a new polymer made ...U. Iowa researchers improve Huntington's disease symptoms in mice
...e models that develop disease more slowly and more closely resemble HD in humans," Davidson said. Most genes are inherited as a pair, one from either parent. In HD, one mutated copy of the gene is sufficient to cause the disease. However, the normal Huntington gene produces a protein that is known to be cri...Lipids get new comprehensive classification system
...ed by LIPID MAPS follow existing IUPAC-IUBMB rules closely and should not be viewed as a competing format," emphasizes Dr. Fahy. "The main differences involve clarification of the use of core structures to simplify systematic naming of some of the more complex lipids, provision of systematic names for recent...Researchers reveal secrets of flying snakes
...hout injury. The researchers now are looking more closely at the aerodynamic issues. They plan to use physical and computer models to study the more complex kinematics of these gliders. To collect and study these snakes, Socha traveled to Singapore twice and Thailand once with grants from National Geograph...Enzyme's newly discovered role may make it target for arthritis treatment
...owing that mice deficient in cathepsin G and other closely related proteases failed to develop arthritis after the injections. This led them to look for the mechanisms by which these proteases regulate inflammation. Observations made by Pham's lab and other groups had linked the earliest stages of inflammat...